about
In silico prediction of physical protein interactions and characterization of interactome orphansGenome-wide generation and systematic phenotyping of knockout mice reveals new roles for many genesFundamentals of protein interaction network mappingFocusing on shared subpockets - new developments in fragment-based drug discoveryIntegrative approaches for finding modular structure in biological networksAdvancing Biological Understanding and Therapeutics Discovery with Small-Molecule ProbesPersonalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistanceThe pharmacological landscape and therapeutic potential of serine hydrolasesImproving and accelerating drug development for nervous system disordersStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewThe Cryptosporidium parvum KinomeFamily-wide chemical profiling and structural analysis of PARP and tankyrase inhibitorsMultiple knockout mouse models reveal lincRNAs are required for life and brain developmentMass Spectrometry-Based Approaches to Understand the Molecular Basis of MemoryContributions of academic laboratories to the discovery and development of chemical biology toolsHuman SRMAtlas: A Resource of Targeted Assays to Quantify the Complete Human ProteomeEnabling large-scale design, synthesis and validation of small molecule protein-protein antagonistsOpen access target validation is a more efficient way to accelerate drug discoveryDisulfide-Trapping Identifies a New, Effective Chemical Probe for Activating the Nuclear Receptor Human LRH-1 (NR5A2)Accelerating target discovery using pre-competitive open science-patients need faster innovation more than anyone elseDynamics of the discovery process of protein-protein interactions from low content studiesApplications of chemogenomic library screening in drug discoveryIdentification of genes important for cutaneous function revealed by a large scale reverse genetic screen in the mouseAntibody-siRNA conjugates: drugging the undruggable for anti-leukemic therapy.Subcellular localization of K+ channels in mammalian brain neurons: remarkable precision in the midst of extraordinary complexity.Activity-based proteomic and metabolomic approaches for understanding metabolismSeeding collaborations to advance kinase science with the GSK Published Kinase Inhibitor Set (PKIS)A gene expression resource generated by genome-wide lacZ profiling in the mouse.Review: High-performance computing to detect epistasis in genome scale data sets.Reproducible quantitative proteotype data matrices for systems biology.Data-Driven Approach To Determine Popular Proteins for Targeted Proteomics Translation of Six Organ SystemsPredicting gene ontology from a global meta-analysis of 1-color microarray experiments.How chemoproteomics can enable drug discovery and developmentA novel protein kinase-like domain in a selenoprotein, widespread in the tree of life.Reproducible quantification of cancer-associated proteins in body fluids using targeted proteomics.Exon level transcriptomic profiling of HIV-1-infected CD4(+) T cells reveals virus-induced genes and host environment favorable for viral replication.The promise and peril of chemical probes.Parallel immunizations of rabbits using the same antigen yield antibodies with similar, but not identical, epitopesN-glycoprotein SRMAtlas: a resource of mass spectrometric assays for N-glycosites enabling consistent and multiplexed protein quantification for clinical applications.Analytical challenges translating mass spectrometry-based phosphoproteomics from discovery to clinical applications.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Too many roads not taken
@ast
Too many roads not taken
@en
Too many roads not taken
@nl
type
label
Too many roads not taken
@ast
Too many roads not taken
@en
Too many roads not taken
@nl
prefLabel
Too many roads not taken
@ast
Too many roads not taken
@en
Too many roads not taken
@nl
P50
P3181
P356
P1433
P1476
Too many roads not taken
@en
P2093
Stephen V Frye
Timothy M Willson
P2888
P3181
P356
10.1038/470163A
P407
P577
2011-02-10T00:00:00Z
P6179
1045497536