A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission
about
Crystal structure of the p38 alpha-MAPKAP kinase 2 heterodimerMxi2 promotes stimulus-independent ERK nuclear translocationInteracting JNK-docking sites in MKK7 promote binding and activation of JNK mitogen-activated protein kinasesA walk-through of the yeast mating pheromone response pathwayMitogen-activated protein kinase signaling in plants under abiotic stressSelectivity of docking sites in MAPK kinasesIdentification of mitogen-activated protein kinase docking sites in enzymes that metabolize phosphatidylinositols and inositol phosphates.Persistent activation by constitutive Ste7 promotes Kss1-mediated invasive growth but fails to support Fus3-dependent mating in yeast.Specificity of MAP kinase signaling in yeast differentiation involves transient versus sustained MAPK activationNbp2 targets the Ptc1-type 2C Ser/Thr phosphatase to the HOG MAPK pathway.Differential input by Ste5 scaffold and Msg5 phosphatase route a MAPK cascade to multiple outcomesRegulation of the yeast amphiphysin homologue Rvs167p by phosphorylation.A docking site in MKK4 mediates high affinity binding to JNK MAPKs and competes with similar docking sites in JNK substratesIdentification of a motif in the carboxyl terminus of beta -arrestin2 responsible for activation of JNK3ERK2 shows a restrictive and locally selective mechanism of recognition by its tyrosine phosphatase inactivators not shared by its activator MEK1Mitogen-activated protein kinase signaling in the heart: angels versus demons in a heart-breaking tale.Computational prediction and experimental verification of new MAP kinase docking sites and substrates including Gli transcription factorsRac-PAK signaling stimulates extracellular signal-regulated kinase (ERK) activation by regulating formation of MEK1-ERK complexesA critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation.Arabidopsis MKS1 is involved in basal immunity and requires an intact N-terminal domain for proper function.Engineered single nucleotide polymorphisms in the mosquito MEK docking site alter Plasmodium berghei development in Anopheles gambiae.Mitogen-activated protein kinases with distinct requirements for Ste5 scaffolding influence signaling specificity in Saccharomyces cerevisiaeCytoplasmic localization of Wis1 MAPKK by nuclear export signal is important for nuclear targeting of Spc1/Sty1 MAPK in fission yeast.Combining docking site and phosphosite predictions to find new substrates: identification of smoothelin-like-2 (SMTNL2) as a c-Jun N-terminal kinase (JNK) substrateGenetic evidence for Shc requirement in TCR-induced c-Rel nuclear translocation and IL-2 expression.Trichoderma mitogen-activated protein kinase signaling is involved in induction of plant systemic resistance.Docking sites on mitogen-activated protein kinase (MAPK) kinases, MAPK phosphatases and the Elk-1 transcription factor compete for MAPK binding and are crucial for enzymic activity.Activation of ERK induces phosphorylation of MAPK phosphatase-7, a JNK specific phosphatase, at Ser-446.Rice mitogen-activated protein kinase interactome analysis using the yeast two-hybrid system.Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125.Characterization of an ERK-binding domain in microphthalmia-associated transcription factor and differential inhibition of ERK2-mediated substrate phosphorylation.Analysis of mitogen-activated protein kinase activation and interactions with regulators and substratesMechanisms of MAPK signalling specificity.Mitogen-activated protein kinase (MAPK)-docking sites in MAPK kinases function as tethers that are crucial for MAPK regulation in vivo.Optical control of cell signaling by single-chain photoswitchable kinasesTight interconnection and multi-level control of Arabidopsis MYB44 in MAPK cascade signalling.Rice mitogen activated protein kinase kinase and mitogen activated protein kinase interaction network revealed by in-silico docking and yeast two-hybrid approaches.Solution NMR insights into docking interactions involving inactive ERK2Consequences and utility of the zinc-dependent metalloprotease activity of anthrax lethal toxin.Mapping the binding interface of ERK and transcriptional repressor Capicua using photocrosslinking.
P2860
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P2860
A conserved docking site in MEKs mediates high-affinity binding to MAP kinases and cooperates with a scaffold protein to enhance signal transmission
description
2001 nî lūn-bûn
@nan
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
A conserved docking site in ME ...... to enhance signal transmission
@ast
A conserved docking site in ME ...... to enhance signal transmission
@en
A conserved docking site in ME ...... to enhance signal transmission
@nl
type
label
A conserved docking site in ME ...... to enhance signal transmission
@ast
A conserved docking site in ME ...... to enhance signal transmission
@en
A conserved docking site in ME ...... to enhance signal transmission
@nl
prefLabel
A conserved docking site in ME ...... to enhance signal transmission
@ast
A conserved docking site in ME ...... to enhance signal transmission
@en
A conserved docking site in ME ...... to enhance signal transmission
@nl
P2093
P2860
P356
P1476
A conserved docking site in ME ...... to enhance signal transmission
@en
P2093
A J Bardwell
K Matsukuma
L J Flatauer
P2860
P304
P356
10.1074/JBC.M010271200
P407
P50
P577
2001-03-30T00:00:00Z