The 100-kda U5 snRNP protein (hPrp28p) contacts the 5' splice site through its ATPase site
about
Prp8 protein: at the heart of the spliceosomep68 RNA helicase is an essential human splicing factor that acts at the U1 snRNA-5' splice site duplex.Structure and function of an RNase H domain at the heart of the spliceosomeCrystal structure of human spliceosomal U1 snRNP at 5.5 Å resolutionStructural and functional analysis of the human spliceosomal DEAD-box helicase Prp28Splicing proofreading at 5' splice sites by ATPase Prp28p.Genetic interactions with CLF1 identify additional pre-mRNA splicing factors and a link between activators of yeast vesicular transport and splicing.The ATP requirement for U2 snRNP addition is linked to the pre-mRNA region 5' to the branch site.Defining a 5' splice site by functional selection in the presence and absence of U1 snRNA 5' end.p54(nrb) associates with the 5' splice site within large transcription/splicing complexes.A conformational rearrangement in the spliceosome sets the stage for Prp22-dependent mRNA release.Stable tri-snRNP integration is accompanied by a major structural rearrangement of the spliceosome that is dependent on Prp8 interaction with the 5' splice site.Group II intron lariat: Structural insights into the spliceosome.A spliceosome intermediate with loosely associated tri-snRNP accumulates in the absence of Prp28 ATPase activityAn unanticipated early function of DEAD-box ATPase Prp28 during commitment to splicing is modulated by U5 snRNP protein Prp8.Identification and in silico analysis of cattle DExH/D box RNA helicases.Structural analysis of the spliceosomal RNA helicase Prp28 from the thermophilic eukaryote Chaetomium thermophilum.Mutations in the U5 snRNA result in altered splicing of subsets of pre-mRNAs and reduced stability of Prp8.Alternative splicing of type II procollagen exon 2 is regulated by the combination of a weak 5' splice site and an adjacent intronic stem-loop cis element.Prespliceosome structure provides insights into spliceosome assembly and regulation
P2860
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P2860
The 100-kda U5 snRNP protein (hPrp28p) contacts the 5' splice site through its ATPase site
description
2001 nî lūn-bûn
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2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
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2001 թվականի փետրվարին հրատարակված գիտական հոդված
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2001年の論文
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name
The 100-kda U5 snRNP protein ( ...... e site through its ATPase site
@ast
The 100-kda U5 snRNP protein ( ...... e site through its ATPase site
@en
The 100-kda U5 snRNP protein ( ...... e site through its ATPase site
@nl
type
label
The 100-kda U5 snRNP protein ( ...... e site through its ATPase site
@ast
The 100-kda U5 snRNP protein ( ...... e site through its ATPase site
@en
The 100-kda U5 snRNP protein ( ...... e site through its ATPase site
@nl
prefLabel
The 100-kda U5 snRNP protein ( ...... e site through its ATPase site
@ast
The 100-kda U5 snRNP protein ( ...... e site through its ATPase site
@en
The 100-kda U5 snRNP protein ( ...... e site through its ATPase site
@nl
P2093
P2860
P3181
P1433
P1476
The 100-kda U5 snRNP protein ( ...... e site through its ATPase site
@en
P2093
P2860
P304
P3181
P356
10.1017/S1355838201001807
P407
P577
2001-02-01T00:00:00Z