Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
about
USP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1Role of Deubiquitinating Enzymes in DNA RepairNew perspectives on oxidized genome damage and repair inhibition by pro-oxidant metals in neurological diseasesA Structural Element within the HUWE1 HECT Domain Modulates Self-ubiquitination and Substrate Ubiquitination ActivitiesBase Excision Repair, a Pathway Regulated by Posttranslational ModificationsTCRP1 contributes to cisplatin resistance by preventing Pol β degradation in lung cancer cellsp53 coordinates base excision repair to prevent genomic instabilityBioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage.Base excision repair: a critical player in many gamesAPE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functionsE3 ubiquitin ligase Mule ubiquitinates Miz1 and is required for TNFalpha-induced JNK activation.Mammalian base excision repair: the forgotten archangelPosttranslational modification of mammalian AP endonuclease (APE1).HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase βThe role of epigenetics in personalized medicine: challenges and opportunities.The EEL-1 ubiquitin ligase promotes DNA damage-induced germ cell apoptosis in C. elegansRegulation of the DNA damage response by ubiquitin conjugation.Reduced association of anti-apoptotic protein Mcl-1 with E3 ligase Mule increases the stability of Mcl-1 in breast cancer cells.ATM prevents DSB formation by coordinating SSB repair and cell cycle progression.Cells deficient in base-excision repair reveal cancer hallmarks originating from adjustments to genetic instability.Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stabilityRegulation of oxidative DNA damage repair by DNA polymerase λ and MutYH by cross-talk of phosphorylation and ubiquitination.The E3 ubiquitin ligase Mule acts through the ATM-p53 axis to maintain B lymphocyte homeostasis.Ring finger protein 146/Iduna is a poly(ADP-ribose) polymer binding and PARsylation dependent E3 ubiquitin ligase.DNA damage-induced activation of CUL4B targets HUWE1 for proteasomal degradation.Phosphorylation of PNKP by ATM prevents its proteasomal degradation and enhances resistance to oxidative stress.Syk-mediated tyrosine phosphorylation of mule promotes TNF-induced JNK activation and cell deathHUWE1 mutations in Juberg-Marsidi and Brooks syndromes: the results of an X-chromosome exome sequencing study.Mule/Huwe1/Arf-BP1 suppresses Ras-driven tumorigenesis by preventing c-Myc/Miz1-mediated down-regulation of p21 and p15Targeting DNA polymerase ß for therapeutic intervention.HUWE1 is a critical colonic tumour suppressor gene that prevents MYC signalling, DNA damage accumulation and tumour initiationRegulation of human MutYH DNA glycosylase by the E3 ubiquitin ligase mule.Cellular accumulation of Cys326-OGG1 protein complexes under conditions of oxidative stress.Apoptosis and oncogenesis: give and take in the BCL-2 family.The emerging role of Mule and ARF in the regulation of base excision repair.Base excision repair targets for cancer therapyOxidized base damage and single-strand break repair in mammalian genomes: role of disordered regions and posttranslational modifications in early enzymes.Reprogramming cellular events by poly(ADP-ribose)-binding proteinsMonitoring regulation of DNA repair activities of cultured cells in-gel using the comet assay.Dichotomous role of pancreatic HUWE1/MULE/ARF-BP1 in modulating beta cell apoptosis in mice under physiological and genotoxic conditions.
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P248
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P2860
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
description
2009 nî lūn-bûn
@nan
2009 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@ast
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@en
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@en-gb
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@nl
type
label
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@ast
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@en
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@en-gb
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@nl
prefLabel
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@ast
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@en
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@en-gb
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@nl
P2093
P2860
P50
P921
P3181
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P1476
Ubiquitin ligase ARF-BP1/Mule modulates base excision repair
@en
P2093
David Finch
Grigory L Dianov
Irina I Dianova
Ricky A Sharma
Svetlana V Khoronenkova
W Gillies McKenna
P2860
P304
P3181
P356
10.1038/EMBOJ.2009.243
P407
P577
2009-10-21T00:00:00Z