α-Synuclein protects against manganese neurotoxic insult during the early stages of exposure in a dopaminergic cell model of Parkinson's disease - Test2 - elhamkhani - TriplyDB

α-Synuclein protects against manganese neurotoxic insult during the early stages of exposure in a dopaminergic cell model of Parkinson's disease

α-Synuclein protects against manganese neurotoxic insult during the early stages of exposure in a dopaminergic cell model of Parkinson's disease

http://www.wikidata.org/entity/Q28386621

about

Untangling the Manganese-α-Synuclein Web Role of ROS and RNS Sources in Physiological and Pathological Conditions Metals and Neurodegeneration Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases "Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies"Disease-toxicant interactions in Parkinson's disease neuropathology Mutant alpha-synuclein causes age-dependent neuropathology in monkey brain Gut microbiome in health and disease: Linking the microbiome-gut-brain axis and environmental factors in the pathogenesis of systemic and neurodegenerative diseases Copper-induced structural conversion templates prion protein oligomerization and neurotoxicity.Re-Cloning the N27 Dopamine Cell Line to Improve a Cell Culture Model of Parkinson's Disease.Alterations in mitochondrial dynamics induced by tebufenpyrad and pyridaben in a dopaminergic neuronal cell culture model.Molecular cloning, epigenetic regulation, and functional characterization of Prkd1 gene promoter in dopaminergic cell culture models of Parkinson's disease.Protein kinase Cδ upregulation in microglia drives neuroinflammatory responses and dopaminergic neurodegeneration in experimental models of Parkinson's disease.Manganese exposure induces neuroinflammation by impairing mitochondrial dynamics in astrocytes.Neuronal protection against oxidative insult by polyanhydride nanoparticle-based mitochondria-targeted antioxidant therapy.Role of neurotoxicants and traumatic brain injury in α-synuclein protein misfolding and aggregation.Impulse control disorder, lysosomal malfunction and ATP13A2 insufficiency in Parkinsonism.Mechanisms of Gene-Environment Interactions in Parkinson's Disease.Exosomes in Toxicology: Relevance to Chemical Exposure and Pathogenesis of Environmentally Linked Diseases.Affected energy metabolism under manganese stress governs cellular toxicity.p73 gene in dopaminergic neurons is highly susceptible to manganese neurotoxicity.α-Synuclein Enhances Cadmium Uptake and Neurotoxicity via Oxidative Stress and Caspase Activated Cell Death Mechanisms in a Dopaminergic Cell Model of Parkinson's Disease.Manganese exposure exacerbates progressive motor deficits and neurodegeneration in the MitoPark mouse model of Parkinson's disease: Relevance to gene and environment interactions in metal neurotoxicity.Inflammatory Activation of Microglia and Astrocytes in Manganese Neurotoxicity.Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders.Synergistic protective effect of paeoniflorin and β-ecdysterone against rotenone-induced neurotoxicity in PC12 cells.Mitochondria: A Common Target for Genetic Mutations and Environmental Toxicants in Parkinson's Disease.Environmental neurotoxicant manganese regulates exosome-mediated extracellular miRNAs in cell culture model of Parkinson's disease: Relevance to α-synuclein misfolding in metal neurotoxicity.

P2860

Q26740340-004CB399-8820-4A76-B731-4D186112CDD2 Q26740342-5B113B87-8FE6-4112-9EF4-3C7434D0F892 Q26752441-C0EC4FE6-989B-4424-B83C-A1B47A3CC005 Q26821835-51426172-99BE-45CA-90D6-AA1F85478978 Q28067566-215B53B1-E812-4BF1-9246-C4EBF112FF45 Q29248297-BCAD555B-0820-4158-88C7-A0D0E8DAB7F5 Q35649563-BB1C7A43-2F7D-44B1-AFE1-B9DC0E8A49A7 Q35858073-11BB3ADA-F44C-4AEA-B91B-6DD44F0D2D9C Q36078399-FBA7E89B-1D6A-4492-B97A-4F3D8E01DC28 Q36101048-63537169-EE81-4C50-8DFC-A0FCFBA077C6 Q36422034-DBD23C53-CA34-42AD-B2B4-B42EE06634AE Q36821650-F13A7F92-022B-4AA5-A588-368781EFAEE7 Q37198050-11B0F08B-28D9-41C4-887C-62D2D0A00C76 Q38702403-E4374957-BA0B-4D88-AE85-E2592A5C1CBE Q38738244-FF7EC843-9695-458F-BBEA-AF7248F1CEA5 Q39043644-6EC41259-4938-4D98-BEC5-491980216411 Q39044609-87E97188-8884-4C86-8F40-B97F59B60FE1 Q39247520-5DA5F37E-D921-498B-9F5D-B86C6E5A0BCD Q39307101-BC273B8D-7075-4DC9-B198-59E79EB0FD0A Q41717643-941D49F1-99FA-4C7C-AA1C-3F3DA64DFEE8 Q42492256-DDBDC9C7-553D-4963-B70F-46930E550126 Q42507829-FEA70E8D-51E4-4E20-AC45-C61DF6213508 Q42510777-5888EE38-6A3C-4EAC-AEFE-6B50350435C9 Q46309590-AD6314B7-FF70-4D44-A1B5-5298E7B51630 Q46309597-94FAD881-01BF-43CE-BF8F-017FC0A8BA8D Q46470336-B80F3FE0-FB95-444A-A9A8-9A07A4FA3312 Q47147993-72EC7B02-AD69-4907-84DF-C5616AA72059 Q51031453-20B05268-AFF1-430E-96FF-5FA46D101217

P2860

α-Synuclein protects against manganese neurotoxic insult during the early stages of exposure in a dopaminergic cell model of Parkinson's disease

http://www.wikidata.org/entity/Q28386621

description

2015 nî lūn-bûn

@nan

2015 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2015 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2015年の論文

@ja

2015年論文

@yue

2015年論文

@zh-hant

2015年論文

@zh-hk

2015年論文

@zh-mo

2015年論文

@zh-tw

2015年论文

@wuu

name

α-Synuclein protects against m ...... l model of Parkinson's disease

@ast

α-Synuclein protects against m ...... l model of Parkinson's disease

@en

α-Synuclein protects against m ...... l model of Parkinson's disease

@nl

type

label

α-Synuclein protects against m ...... l model of Parkinson's disease

@ast

α-Synuclein protects against m ...... l model of Parkinson's disease

@en

α-Synuclein protects against m ...... l model of Parkinson's disease

@nl

altLabel

α-Synuclein Protects Against M ...... l Model of Parkinson’s Disease

@en

prefLabel

α-Synuclein protects against m ...... l model of Parkinson's disease

@ast

α-Synuclein protects against m ...... l model of Parkinson's disease

@en

α-Synuclein protects against m ...... l model of Parkinson's disease

@nl

P1433

Q28386621-39182D5E-D29D-439A-8129-569749ED1E35

P1476

Q28386621-96B2C90B-AD06-41EE-9330-A216EFCDDCD1

P2093

Q28386621-17169D9F-1AEE-4334-A9A3-2BFF5E5F7E22

Q28386621-424BAA82-A11A-466F-AAAE-B9C2127DD81D

Q28386621-74ABBC09-3895-4178-85F9-338CEC769AC8

Q28386621-89736762-D618-4978-9472-95040DA7B03D

P2860

Q28386621-03555E59-DE69-439F-AE62-D24ADAD292BF

Q28386621-0D4B5B84-3CF4-4A38-ABA0-C0F6B6931E0E

Q28386621-1B233C34-340D-4BB7-B319-DE7291AB69E1

Q28386621-2A1A255B-6BCD-40CB-940D-FA751E0A2CD1

Q28386621-31BD47B5-2105-4B35-9BB7-387D96DC2BBA

Q28386621-33DBB8A2-8559-41FF-A300-C3C1CE1933B8

Q28386621-3C6BE447-8FB3-41D9-B44F-8158F5D4D8D3

Q28386621-411431C7-A6A5-4049-ACC9-662FCA9876CF

Q28386621-57DBB2FA-8C7B-4A15-8465-C8FD416CC80F

Q28386621-5A6591DC-9653-44EC-98DE-9C9129F13201

P304

Q28386621-84387813-B71A-4FCA-BD75-79AB5A1D198F

P31

Q28386621-CEDBFE54-46CF-4335-B192-D22DBEFB0281

P3181

Q28386621-15DD53A3-618B-4AEB-A7D5-DA1300C1B04D

P356

Q28386621-95CA1A96-985D-4AE3-9277-F03B0590C0BC

P407

Q28386621-9DBCCE06-D323-4468-B0BE-1CEE3B593301

P433

Q28386621-AA6CF2D4-956D-4570-9DFE-ABA4BB045FE1

P478

Q28386621-5C9244D1-C100-454F-9B09-D25BD914A67B

P50

Q28386621-88B8FA44-1871-4534-AF43-96C8BFDE3A0B

P577

Q28386621-062D652F-6CCB-4589-9471-91850C3A8C58

P5875

Q28386621-7EADAC16-698F-4062-8560-ACBC82963B48

P698

Q28386621-54AEC59F-04A6-4DEA-BF1E-8D7CD66FEEE8

P921

Q28386621-4077BF64-28DD-432D-98BB-D3A7AF1F02DE

Q28386621-9EA0F3B3-3303-4EDA-9E7D-19C15819FF83

Q28386621-A91D4907-5FC4-41B2-9FF0-10935432CE80

Q28386621-D18CA63D-38D0-4797-AFF0-CF5DFAD1656F

P932

Q28386621-32E95A88-22DB-4D06-A83F-EDED4F86B5CE

P3181

P356

P1433

Toxicological Sciences

P1476

α-Synuclein protects against m ...... l model of Parkinson's disease

@en

P2093

Anumantha G Kanthasamy

http://www.w3.org/2001/XMLSchema#string

Arthi Kanthasamy

http://www.w3.org/2001/XMLSchema#string

Huajun Jin

http://www.w3.org/2001/XMLSchema#string

Vellareddy Anantharam

http://www.w3.org/2001/XMLSchema#string

P2860

Manganese exposure among smelting workers: blood manganese-iron ratio as a novel tool for manganese exposure assessment

Mutant and wild-type alpha-synuclein interact with mitochondrial cytochrome C oxidase

Disease-toxicant interactions in manganese exposed Huntington disease mice: early changes in striatal neuron morphology and dopamine metabolism

Aggresomes formed by alpha-synuclein and synphilin-1 are cytoprotective

Manganese neurotoxicity: new perspectives from behavioral, neuroimaging, and neuropathological studies in humans and non-human primates

In vivo measurement of brain GABA concentrations by magnetic resonance spectroscopy in smelters occupationally exposed to manganese

Vanadium induces dopaminergic neurotoxicity via protein kinase Cdelta dependent oxidative signaling mechanisms: relevance to etiopathogenesis of Parkinson's disease

Manganese exposure induces α-synuclein aggregation in the frontal cortex of non-human primates

α-Synuclein negatively regulates protein kinase Cδ expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity

Effect of the overexpression of wild-type or mutant alpha-synuclein on cell susceptibility to insult.

P304

454-468

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

320581

http://www.w3.org/2001/XMLSchema#string

P356

10.1093/TOXSCI/KFU247

http://www.w3.org/2001/XMLSchema#string

P407

P433

2

http://www.w3.org/2001/XMLSchema#string

P478

143

http://www.w3.org/2001/XMLSchema#string

P50

Dilshan S Harischandra

P577

2015-02-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

268790157

http://www.w3.org/2001/XMLSchema#string

P698

25416158

http://www.w3.org/2001/XMLSchema#string

P921

Parkinson's disease

P932

4306724

http://www.w3.org/2001/XMLSchema#string