about
Model systems of protein-misfolding diseases reveal chaperone modifiers of proteotoxicityA dynamic interface between ubiquitylation and cAMP signalingProtein Folding and Mechanisms of ProteostasisGraded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome PathwayDisassembly of Lys11 and mixed linkage polyubiquitin conjugates provides insights into function of proteasomal deubiquitinases Rpn11 and Ubp6.Trial Watch: Proteasomal inhibitors for anticancer therapyMediation of organismal aging and somatic proteostasis by the germlineThe carbohydrate-binding domain of overexpressed STBD1 is important for its stability and protein-protein interactionsA chaperome subnetwork safeguards proteostasis in aging and neurodegenerative diseaseGrand challenges in cellular biochemistry: the "next-gen" biochemistryProteasomal control of cytokinin synthesis protects Mycobacterium tuberculosis against nitric oxideMeta-Analysis of Large-Scale Toxicogenomic Data Finds Neuronal Regeneration Related Protein and Cathepsin D to Be Novel Biomarkers of Drug-Induced ToxicityAn iron-regulated and glycosylation-dependent proteasomal degradation pathway for the plasma membrane metal transporter ZIP14Proteasomal degradation of O-GlcNAc transferase elevates hypoxia-induced vascular endothelial inflammatory response†.Regulating the 20S proteasome ubiquitin-independent degradation pathway.Survival of mycobacteria depends on proteasome-mediated amino acid recycling under nutrient limitationSynergistic effects on dopamine cell death in a Drosophila model of chronic toxin exposure.Upregulation of Unc-51-like kinase 1 by nitric oxide stabilizes SIRT1, independent of autophagy.Expression of FSHD-related DUX4-FL alters proteostasis and induces TDP-43 aggregationMulticolor monitoring of the proteasome's catalytic signature.Maturation of the proteasome core particle induces an affinity switch that controls regulatory particle associationRegulation of immunoproteasome function in the lung.Base-CP proteasome can serve as a platform for stepwise lid formationGates, Channels, and Switches: Elements of the Proteasome MachineProteasome Dysfunction Associated to Oxidative Stress and Proteotoxicity in Adipocytes Compromises Insulin Sensitivity in Human Obesity.Paradoxical resistance of multiple myeloma to proteasome inhibitors by decreased levels of 19S proteasomal subunits.Nano-liquid Chromatography-orbitrap MS-based Quantitative Proteomics Reveals Differences Between the Mechanisms of Action of Carnosic Acid and Carnosol in Colon Cancer Cells.Proteasome function is not impaired in healthy aging of the lung.T2D and Depression Risk Gene Proteasome Modulator 9 is Linked to Insomnia.Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis.Systems view of adipogenesis via novel omics-driven and tissue-specific activity scoring of network functional modules.Characterization of Dynamic UbR-Proteasome Subcomplexes by In vivo Cross-linking (X) Assisted Bimolecular Tandem Affinity Purification (XBAP) and Label-free Quantitation.Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease.APEH Inhibition Affects Osteosarcoma Cell Viability via Downregulation of the Proteasome.The pleiotropic deubiquitinase Ubp3 confers aneuploidy tolerance.Genetics of proteasome diseases.Agouti Related Peptide Secreted Via Human Mesenchymal Stem Cells Upregulates Proteasome Activity in an Alzheimer's Disease Model.The Mechanistic Links Between Proteasome Activity, Aging and Age-related Diseases.E3 Ligase RNF126 Directly Ubiquitinates Frataxin, Promoting Its Degradation: Identification of a Potential Therapeutic Target for Friedreich Ataxia.Reversible phosphorylation of the 26S proteasome.
P2860
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P2860
description
2014 nî lūn-bûn
@nan
2014 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2014年の論文
@ja
2014年論文
@yue
2014年論文
@zh-hant
2014年論文
@zh-hk
2014年論文
@zh-mo
2014年論文
@zh-tw
2014年论文
@wuu
name
Regulation of proteasome activity in health and disease
@ast
Regulation of proteasome activity in health and disease
@en
Regulation of proteasome activity in health and disease
@nl
type
label
Regulation of proteasome activity in health and disease
@ast
Regulation of proteasome activity in health and disease
@en
Regulation of proteasome activity in health and disease
@nl
prefLabel
Regulation of proteasome activity in health and disease
@ast
Regulation of proteasome activity in health and disease
@en
Regulation of proteasome activity in health and disease
@nl
P2860
P3181
P1476
Regulation of proteasome activity in health and disease
@en
P2093
Daniel Finley
Marion Schmidt
P2860
P3181
P356
10.1016/J.BBAMCR.2013.08.012
P407
P577
2014-01-01T00:00:00Z