Predicting protein ligand binding sites by combining evolutionary sequence conservation and 3D structure
about
Protein-ligand binding site recognition using complementary binding-specific substructure comparison and sequence profile alignment3DLigandSite: predicting ligand-binding sites using similar structuresCOFACTOR: an accurate comparative algorithm for structure-based protein function annotationCauses of evolutionary rate variation among protein sitesProteins and Their Interacting Partners: An Introduction to Protein-Ligand Binding Site Prediction MethodsStructure-based Methods for Computational Protein Functional Site PredictionMolecular mechanisms of disease-causing missense mutationsThe use of evolutionary patterns in protein annotationCrystal structure of a metal-dependent phosphoesterase (YP_910028.1) from Bifidobacterium adolescentis: Computational prediction and experimental validation of phosphoesterase activityStructural insights into WcbI, a novel polysaccharide-biosynthesis enzymeCalculating an optimal box size for ligand docking and virtual screening against experimental and predicted binding pocketsImproving protein-ligand binding site prediction accuracy by classification of inner pocket points using local featuresA survey of computational intelligence techniques in protein function predictionAlignment of distantly related protein structures: algorithm, bound and implications to homology modelingAccurate protein structure annotation through competitive diffusion of enzymatic functions over a network of local evolutionary similaritiesExploring the landscape of protein-ligand interaction energy using probabilistic approachUsing multiple microenvironments to find similar ligand-binding sites: application to kinase inhibitor bindingPredicting Ligand Binding Sites on Protein Surfaces by 3-Dimensional Probability Density Distributions of Interacting AtomswebPDBinder: a server for the identification of ligand binding sites on protein structuresProtein ligand-specific binding residue predictions by an ensemble classifierModBase, a database of annotated comparative protein structure models and associated resources.Assessment of ligand binding site predictions in CASP10Emerging Computational Methods for the Rational Discovery of Allosteric Drugs.Developing eThread pipeline using SAGA-pilot abstraction for large-scale structural bioinformatics.Algorithmic approaches to protein-protein interaction site prediction.I-TASSER server: new development for protein structure and function predictionsPoLi: A Virtual Screening Pipeline Based on Template Pocket and Ligand Similarity.Detection of secondary binding sites in proteins using fragment screeningProtein Structure and Function Prediction Using I-TASSERAutoSite: an automated approach for pseudo-ligands prediction-from ligand-binding sites identification to predicting key ligand atoms.Development of a protein-ligand-binding site prediction method based on interaction energy and sequence conservation.DEPTH: a web server to compute depth and predict small-molecule binding cavities in proteinsThe Protein Structure Initiative Structural Biology Knowledgebase Technology Portal: a structural biology web resource.Functional region prediction with a set of appropriate homologous sequences--an index for sequence selection by integrating structure and sequence information with spatial statistics.Structural and dynamic determinants of protein-peptide recognition.Structural basis for recognition of Emi2 by Polo-like kinase 1 and development of peptidomimetics blocking oocyte maturation and fertilization.Computational prediction of heme-binding residues by exploiting residue interaction networkFlexibility and binding affinity in protein-ligand, protein-protein and multi-component protein interactions: limitations of current computational approaches.The FGGY carbohydrate kinase family: insights into the evolution of functional specificitiesAPIS: accurate prediction of hot spots in protein interfaces by combining protrusion index with solvent accessibility.
P2860
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P2860
Predicting protein ligand binding sites by combining evolutionary sequence conservation and 3D structure
description
2009 nî lūn-bûn
@nan
2009 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Predicting protein ligand bind ...... conservation and 3D structure
@ast
Predicting protein ligand bind ...... conservation and 3D structure
@en
Predicting protein ligand bind ...... conservation and 3D structure
@nl
type
label
Predicting protein ligand bind ...... conservation and 3D structure
@ast
Predicting protein ligand bind ...... conservation and 3D structure
@en
Predicting protein ligand bind ...... conservation and 3D structure
@nl
prefLabel
Predicting protein ligand bind ...... conservation and 3D structure
@ast
Predicting protein ligand bind ...... conservation and 3D structure
@en
Predicting protein ligand bind ...... conservation and 3D structure
@nl
P2093
P2860
P3181
P1476
Predicting protein ligand bind ...... conservation and 3D structure
@en
P2093
John A Capra
Mona Singh
Thomas A Funkhouser
P2860
P304
P3181
P356
10.1371/JOURNAL.PCBI.1000585
P407
P577
2009-12-01T00:00:00Z