High-precision, in vitro validation of the sequestration mechanism for generating ultrasensitive dose-response curves in regulatory networks

High-precision, in vitro validation of the sequestration mechanism for generating ultrasensitive dose-response curves in regulatory networks

Item
http://www.wikidata.org/entity/Q28477385
Complete integrability of information processing by biochemical reactionsUltrasensitive response motifs: basic amplifiers in molecular signalling networks.The transcription factor titration effect dictates level of gene expression.Intrinsic disorder as a generalizable strategy for the rational design of highly responsive, allosterically cooperative receptors.Thermodynamic basis for engineering high-affinity, high-specificity binding-induced DNA clamp nanoswitches.Ultra-specific discrimination of single-nucleotide mutations using sequestration-assisted molecular beacons.Re-engineering electrochemical biosensors to narrow or extend their useful dynamic range.Allosterically tunable, DNA-based switches triggered by heavy metals.Using distal-site mutations and allosteric inhibition to tune, extend, and narrow the useful dynamic range of aptamer-based sensors.Engineering biosensors with extended, narrowed, or arbitrarily edited dynamic range.Rational design of allosteric inhibitors and activators using the population-shift model: in vitro validation and application to an artificial biosensor.Using Nature's "Tricks" To Rationally Tune the Binding Properties of Biomolecular Receptors.Using the population-shift mechanism to rationally introduce "Hill-type" cooperativity into a normally non-cooperative receptor.Scaling of gene expression with transcription-factor fugacity.Re-engineering Electrochemical Biosensors To Narrow or Extend Their Useful Dynamic Range
P2860

High-precision, in vitro validation of the sequestration mechanism for generating ultrasensitive dose-response curves in regulatory networks

Item
http://www.wikidata.org/entity/Q28477385
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
High-precision, in vitro valid ...... curves in regulatory networks
@ast
High-precision, in vitro valid ...... curves in regulatory networks
@en
High-precision, in vitro valid ...... curves in regulatory networks
@nl
type
label
High-precision, in vitro valid ...... curves in regulatory networks
@ast
High-precision, in vitro valid ...... curves in regulatory networks
@en
High-precision, in vitro valid ...... curves in regulatory networks
@nl
prefLabel
High-precision, in vitro valid ...... curves in regulatory networks
@ast
High-precision, in vitro valid ...... curves in regulatory networks
@en
High-precision, in vitro valid ...... curves in regulatory networks
@nl
P1433
P1476
P2093
P2860
P304
P31
P3181
P356
P407
P433
P478
P50
P577
P5875
P698
P932
P3181
P356
P1433
P1476
High-precision, in vitro valid ...... curves in regulatory networks
@en
P2093
P2860
P304
P31
P3181
P356
10.1371/JOURNAL.PCBI.1002171
P407
P433
P478
P50
P577
P5875
P698
P932