Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1): marked insensitivity toward different regulatory axes
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Cholesterol 24-hydroxylase: an enzyme of cholesterol turnover in the brain24S-hydroxycholesterol effects on lipid metabolism genes are modeled in traumatic brain injuryHistone deacetylase inhibition decreases cholesterol levels in neuronal cells by modulating key genes in cholesterol synthesis, uptake and effluxTranscriptional events co-regulated by hypoxia and cold stresses in Zebrafish larvaeThe antifungal drug voriconazole is an efficient inhibitor of brain cholesterol 24S-hydroxylase in vitro and in vivoMarked variability in hepatic expression of cytochromes CYP7A1 and CYP27A1 as compared to cerebral CYP46A1. Lessons from a dietary study with omega 3 fatty acids in hamsters.Genetic connections between neurological disorders and cholesterol metabolismEpigenetic regulation of cholesterol homeostasis.Steady-state levels of retinal 24S-hydroxycholesterol are maintained by glial cells intervention after elevation of intraocular pressure in the rat.Cholesterol in brain disease: sometimes determinant and frequently implicated.The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols.Is it possible to improve memory function by upregulation of the cholesterol 24S-hydroxylase (CYP46A1) in the brain?Analysis of bioactive oxysterols in newborn mouse brain by LC/MS.Prosurvival effect of DHCR24/Seladin-1 in acute and chronic responses to oxidative stressCholesterol and 24S-hydroxycholesterol trafficking in Alzheimer's disease.Oxysterols and Alzheimer's disease.Cholesterol loss enhances TrkB signaling in hippocampal neurons aging in vitroCrossing the barrier: oxysterols as cholesterol transporters and metabolic modulators in the brain.On the regulatory role of side-chain hydroxylated oxysterols in the brain. Lessons from CYP27A1 transgenic and Cyp27a1(-/-) miceNeuroendocrine Regulation of MetabolismCortical injury increases cholesterol 24S hydroxylase (Cyp46) levels in the rat brain.Age-dependent increase in desmosterol restores DRM formation and membrane-related functions in cholesterol-free DHCR24-/- mice.Pharmacologic stimulation of cytochrome P450 46A1 and cerebral cholesterol turnover in mice.Advances in methods for the determination of biologically relevant lipid peroxidation products.Prescription of lipophilic statins to Alzheimer's disease patients: some controversies to consider.Regulation of tyrosine kinase B activity by the Cyp46/cholesterol loss pathway in mature hippocampal neurons: relevance for neuronal survival under stress and in aging.In vitro cytochrome P450 46A1 (CYP46A1) activation by neuroactive compounds.The enzyme lecithin-cholesterol acyltransferase esterifies cerebrosterol and limits the toxic effect of this oxysterol on SH-SY5Y cells.Adaptive responses induced by 24S-hydroxycholesterol through liver X receptor pathway reduce 7-ketocholesterol-caused neuronal cell death.24(S)-hydroxycholesterol is actively eliminated from neuronal cells by ABCA1.Neuronal differentiation alters the ratio of Sp transcription factors recruited to the CYP46A1 promoter.Modeling cholesterol metabolism by gene expression profiling in the hippocampus.Targeted lipidomic analysis of oxysterols in the embryonic central nervous system.Transcriptional and post-translational changes in the brain of mice deficient in cholesterol removal mediated by cytochrome P450 46A1 (CYP46A1).Membrane lipid rafts and neurobiology: age-related changes in membrane lipids and loss of neuronal function.A high-cholesterol diet enriched with polyphenols from Oriental plums (Prunus salicina) improves cognitive function and lowers brain cholesterol levels and neurodegenerative-related protein expression in mice.Cholesterol and glycosphingolipids of human trabecular meshwork and aqueous humor: comparative profiles from control and glaucomatous donors.An innate immune response and altered nuclear receptor activation defines the spinal cord transcriptome during alpha-tocopherol deficiency in Ttpa-null mice.Analysis of Gene Regulatory Networks of Maize in Response to Nitrogen.
P2860
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P2860
Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1): marked insensitivity toward different regulatory axes
description
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2006
@ast
im Februar 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/02/17)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/02/17)
@nl
наукова стаття, опублікована в лютому 2006
@uk
name
Studies on the transcriptional ...... ward different regulatory axes
@ast
Studies on the transcriptional ...... ward different regulatory axes
@en
Studies on the transcriptional ...... ward different regulatory axes
@nl
type
label
Studies on the transcriptional ...... ward different regulatory axes
@ast
Studies on the transcriptional ...... ward different regulatory axes
@en
Studies on the transcriptional ...... ward different regulatory axes
@nl
prefLabel
Studies on the transcriptional ...... ward different regulatory axes
@ast
Studies on the transcriptional ...... ward different regulatory axes
@en
Studies on the transcriptional ...... ward different regulatory axes
@nl
P2093
P356
P1476
Studies on the transcriptional ...... ward different regulatory axes
@en
P2093
Anat Brafman
Elena Feinstein
Gösta Eggertsen
Lena Ekström
Maria Olin
Maura Heverin
Millicent Shafir
Steve Meaney
Ulla Andersson
Yoshihiko Ohyama
P304
P356
10.1074/JBC.M505179200
P407
P577
2006-02-17T00:00:00Z