Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice
about
Mre11 assembles linear DNA fragments into DNA damage signaling complexesModeling the study of DNA damage responses in miceTelomere shortening in human diseasesThe response to and repair of RAG-mediated DNA double-strand breaksCell-cycle checkpoints and cancerZIP4H (TEX11) deficiency in the mouse impairs meiotic double strand break repair and the regulation of crossing overAn essential function for NBS1 in the prevention of ataxia and cerebellar defectsRad50 is dispensable for the maintenance and viability of postmitotic tissuesChk2 suppresses the oncogenic potential of DNA replication-associated DNA damageThe Mre11 complex influences DNA repair, synapsis, and crossing over in murine meiosisMre11-Rad50-Nbs complex is required to cap telomeres during Drosophila embryogenesis.Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombinationA type I IFN-dependent DNA damage response regulates the genetic program and inflammasome activation in macrophages.Arginine methylation of MRE11 by PRMT1 is required for DNA damage checkpoint control.Genomic instability, endoreduplication, and diminished Ig class-switch recombination in B cells lacking Nbs1.The MRE11 GAR motif regulates DNA double-strand break processing and ATR activation.The MRN complex in double-strand break repair and telomere maintenance.The telomerase RNA component Terc is required for the tumour-promoting effects of Tert overexpression.The Rad50S allele promotes ATM-dependent DNA damage responses and suppresses ATM deficiency: implications for the Mre11 complex as a DNA damage sensor.DNA double-strand break signaling and human disorders.DNA damage signaling in hematopoietic cells: a role for Mre11 complex repair of topoisomerase lesionsListeria monocytogenes dampens the DNA damage responseCancer risks and mortality in heterozygous ATM mutation carriers.53BP1 and p53 synergize to suppress genomic instability and lymphomagenesis.Drosophila ATM and Mre11 are essential for the G2/M checkpoint induced by low-dose irradiation.Regulation of DNA damage responses and cell cycle progression by hMOB2.Insight into the mechanism of inhibition of adeno-associated virus by the Mre11/Rad50/Nbs1 complexEvidence for distinct functions of MRE11 in Arabidopsis meiosis.The ATM signaling cascade promotes recombination-dependent pachytene arrest in mouse spermatocytes.Spo11 and the Formation of DNA Double-Strand Breaks in Meiosis.V(D)J recombination in zebrafish: Normal joining products with accumulation of unresolved coding ends and deleted signal ends.Genome maintenance defects in cultured cells and mice following partial inactivation of the essential cell cycle checkpoint gene Hus1.Chromosomal instability in oral cancer cells.Cell cycle- and DNA repair pathway-specific effects of apoptosis on tumor suppression.Occupational solvent exposure, genetic variation of DNA repair genes, and the risk of non-Hodgkin's lymphoma.A primary immunodeficiency characterized by defective immunoglobulin class switch recombination and impaired DNA repair.A novel plant gene essential for meiosis is related to the human CtIP and the yeast COM1/SAE2 geneRepair of double-strand breaks by nonhomologous end joining in the absence of Mre11.ATM-dependent DNA damage surveillance in T-cell development and leukemogenesis: the DSB connection.Ataxia telangiectasia mutated kinase controls chronic gammaherpesvirus infection.
P2860
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P2860
Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice
description
2003 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im Dezember 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/12/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/12/01)
@nl
наукова стаття, опублікована в грудні 2003
@uk
مقالة علمية (نشرت في ديسمبر 2003)
@ar
name
Checkpoint failure and chromos ...... sis in Mre11(ATLD1/ATLD1) mice
@ast
Checkpoint failure and chromos ...... sis in Mre11(ATLD1/ATLD1) mice
@en
Checkpoint failure and chromos ...... sis in Mre11(ATLD1/ATLD1) mice
@nl
type
label
Checkpoint failure and chromos ...... sis in Mre11(ATLD1/ATLD1) mice
@ast
Checkpoint failure and chromos ...... sis in Mre11(ATLD1/ATLD1) mice
@en
Checkpoint failure and chromos ...... sis in Mre11(ATLD1/ATLD1) mice
@nl
prefLabel
Checkpoint failure and chromos ...... sis in Mre11(ATLD1/ATLD1) mice
@ast
Checkpoint failure and chromos ...... sis in Mre11(ATLD1/ATLD1) mice
@en
Checkpoint failure and chromos ...... sis in Mre11(ATLD1/ATLD1) mice
@nl
P2093
P1433
P1476
Checkpoint failure and chromos ...... sis in Mre11(ATLD1/ATLD1) mice
@en
P2093
Bret R. Williams
David O. Ferguson
Frederick W. Alt
Jan-Willem F. Theunissen
Mark I. Kaplan
Patricia A. Hunt
P304
P356
10.1016/S1097-2765(03)00455-6
P50
P577
2003-12-01T00:00:00Z