The MRN complex in double-strand break repair and telomere maintenance. - Test2 - elhamkhani - TriplyDB

The MRN complex in double-strand break repair and telomere maintenance.

The MRN complex in double-strand break repair and telomere maintenance.

http://www.wikidata.org/entity/Q34127693

about

Human artificial chromosome (HAC) vector with a conditional centromere for correction of genetic deficiencies in human cells MRE11 and RAD50, but not NBS1, are essential for gene targeting in the moss Physcomitrella patens Telomere- and Telomerase-Associated Proteins and Their Functions in the Plant Cell Radio-resistant mesenchymal stem cells: mechanisms of resistance and potential implications for the clinic DNA Damage and Pulmonary Hypertension The Mre11/Rad50/Nbs1 complex: recent insights into catalytic activities and ATP-driven conformational changes ATP-driven Rad50 conformations regulate DNA tethering, end resection, and ATM checkpoint signaling Effect of MRE11 loss on PARP-inhibitor sensitivity in endometrial cancer in vitro A Decade of Biochemical and Structural Studies of the DNA Repair Machinery of Deinococcus radiodurans: Major Findings, Functional and Mechanistic Insight and Challenges Ubiquitylation, neddylation and the DNA damage response Formation of linear amplicons with inverted duplications in Leishmania requires the MRE11 nuclease Adenovirus core protein VII protects the viral genome from a DNA damage response at early times after infection.Non-homologous end-joining pathway associated with occurrence of myocardial infarction: gene set analysis of genome-wide association study data.Kaposi Sarcoma Herpesvirus (KSHV) Latency-Associated Nuclear Antigen (LANA) recruits components of the MRN (Mre11-Rad50-NBS1) repair complex to modulate an innate immune signaling pathway and viral latency A fine-scale dissection of the DNA double-strand break repair machinery and its implications for breast cancer therapy.RAD50 targeting impairs DNA damage response and sensitizes human breast cancer cells to cisplatin therapy Withaferin-A kills cancer cells with and without telomerase: chemical, computational and experimental evidences.Taking a Bad Turn: Compromised DNA Damage Response in Leukemia Endoplasmic reticulum stress pathway PERK-eIF2α confers radioresistance in oropharyngeal carcinoma by activating NF-κB.Productive replication of human papillomavirus 31 requires DNA repair factor Nbs1.Pathway choice in DNA double strand break repair: observations of a balancing act.NBS1 plays a synergistic role with telomerase in the maintenance of telomeres in Arabidopsis thaliana.Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks Gene and protein responses of human lung tissue explants exposed to ambient particulate matter of different sizes.Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein Telomere-regulating genes and the telomere interactome in familial cancers.Insight into the mechanism of inhibition of adeno-associated virus by the Mre11/Rad50/Nbs1 complex Phosphorylation of SMC1 by ATR is required for desferrioxamine (DFO)-induced apoptosis.DNA damage repair genes controlling human papillomavirus (HPV) episome levels under conditions of stability and extreme instability Choosing the right path: does DNA-PK help make the decision?Role of lamin b1 in chromatin instability The actin depolymerizing factor (ADF)/cofilin signaling pathway and DNA damage responses in cancer Mre11-Rad50 complex crystals suggest molecular calisthenics.The Rad50 coiled-coil domain is indispensable for Mre11 complex functions Adeno-associated virus type 2 modulates the host DNA damage response induced by herpes simplex virus 1 during coinfection.Biomarkers for prognosis and treatment selection in advanced bladder cancer patients.Telomere maintenance genes SIRT1 and XRCC6 impact age-related decline in telomere length but only SIRT1 is associated with human longevity.QTL Mapping and Candidate Gene Analysis of Telomere Length Control Factors in Maize (Zea mays L.).Changing the ubiquitin landscape during viral manipulation of the DNA damage response.Chromosomal Translocations in the Parasite Leishmania by a MRE11/RAD50-Independent Microhomology-Mediated End Joining Mechanism

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The MRN complex in double-strand break repair and telomere maintenance.

http://www.wikidata.org/entity/Q34127693

description

2010 nî lūn-bûn

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2010 թուականի Յուլիսին հրատարակուած գիտական յօդուած

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2010 թվականի հուլիսին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

The MRN complex in double-strand break repair and telomere maintenance.

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The MRN complex in double-strand break repair and telomere maintenance.

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The MRN complex in double-strand break repair and telomere maintenance.

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type

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The MRN complex in double-strand break repair and telomere maintenance.

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The MRN complex in double-strand break repair and telomere maintenance.

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The MRN complex in double-strand break repair and telomere maintenance.

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The MRN complex in double-strand break repair and telomere maintenance.

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The MRN complex in double-strand break repair and telomere maintenance.

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The MRN complex in double-strand break repair and telomere maintenance.

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J.FEBSLET.2010.07.029

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The MRN complex in double-strand break repair and telomere maintenance.

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Brandon J Lamarche

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Matthew D Weitzman

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Nicole I Orazio

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P2860

Nuclear localization and cell cycle-specific expression of CtIP, a protein that associates with the BRCA1 tumor suppressor

Cell-cycle-regulated association of RAD50/MRE11/NBS1 with TRF2 and human telomeres

Rescue of a telomere length defect of Nijmegen breakage syndrome cells requires NBS and telomerase catalytic subunit

ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex

The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage

The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

Human Rad50 is physically associated with human Mre11: identification of a conserved multiprotein complex implicated in recombinational DNA repair

Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

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