RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells
about
ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specificationNotch1 regulates the fate of cardiac progenitor cellsSpecification and function of hemogenic endothelium during embryogenesisGata2b is a restricted early regulator of hemogenic endothelium in the zebrafish embryo.Hematopoietic (stem) cell development - how divergent are the roads taken?Angiopoietin-like proteins stimulate HSPC development through interaction with notch receptor signalingGata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic developmentDirect regulation of Gata3 expression determines the T helper differentiation potential of NotchEndothelio-mesenchymal interaction controls runx1 expression and modulates the notch pathway to initiate aortic hematopoiesisHuman definitive haemogenic endothelium and arterial vascular endothelium represent distinct lineages.Mind bomb-1 is essential for intraembryonic hematopoiesis in the aortic endothelium and the subaortic patches.Modeling reveals bistability and low-pass filtering in the network module determining blood stem cell fate.RBPjkappa-dependent Notch signaling regulates mesenchymal progenitor cell proliferation and differentiation during skeletal developmentNotch signaling distinguishes 2 waves of definitive hematopoiesis in the zebrafish embryo.Notch signaling and neurogenesis in normal and stroke brain.The role of GATA2 in lethal prostate cancer aggressiveness.Searching ChIP-seq genomic islands for combinatorial regulatory codes in mouse embryonic stem cells.Notch signaling functions in retinal pericyte survivalSignalling pathways that control vertebrate haematopoietic stem cell specification.Notch1 regulates progenitor cell proliferation and differentiation during mouse yolk sac hematopoiesis.Hematopoietic stem cell fate is established by the Notch-Runx pathway.Discrete Notch signaling requirements in the specification of hematopoietic stem cells.Induction of hematopoietic differentiation of mouse embryonic stem cells by an AGM-derived stromal cell line is not further enhanced by overexpression of HOXB4.Notch1 acts via Foxc2 to promote definitive hematopoiesis via effects on hemogenic endothelium.The NOTCH signaling pathway in normal and malignant blood cell production.Endothelium and NOTCH specify and amplify aorta-gonad-mesonephros-derived hematopoietic stem cellsLoss-of-function germline GATA2 mutations in patients with MDS/AML or MonoMAC syndrome and primary lymphedema reveal a key role for GATA2 in the lymphatic vasculatureHistone demethylase LSD1-mediated repression of GATA-2 is critical for erythroid differentiationPlasticity and maintenance of hematopoietic stem cells during development.The convergence of Notch and MAPK signaling specifies the blood progenitor fate in the Drosophila mesoderm.GATA2 is required for lymphatic vessel valve development and maintenance.Somite-Derived Retinoic Acid Regulates Zebrafish Hematopoietic Stem Cell FormationNotch signal strength controls cell fate in the haemogenic endotheliumMultiple functions of Notch signaling in self-renewing organs and cancer.Challenges and strategies for generating therapeutic patient-specific hemangioblasts and hematopoietic stem cells from human pluripotent stem cellsRunx1-mediated hematopoietic stem-cell emergence is controlled by a Gata/Ets/SCL-regulated enhancer.Hes repressors are essential regulators of hematopoietic stem cell development downstream of Notch signaling.Uncoupling VEGFA functions in arteriogenesis and hematopoietic stem cell specification.Definitive Hematopoiesis in the Yolk Sac Emerges from Wnt-Responsive Hemogenic Endothelium Independently of Circulation and Arterial Identity.Notch1 activation in embryonic VE-cadherin populations selectively blocks hematopoietic stem cell generation and fetal liver hematopoiesis
P2860
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P2860
RBPjkappa-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells
description
2005 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im März 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/03/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/03/01)
@nl
наукова стаття, опублікована в березні 2005
@uk
مقالة علمية (نشرت في مارس 2005)
@ar
name
RBPjkappa-dependent Notch func ...... -embryonic hematopoietic cells
@ast
RBPjkappa-dependent Notch func ...... -embryonic hematopoietic cells
@en
RBPjkappa-dependent Notch func ...... -embryonic hematopoietic cells
@nl
type
label
RBPjkappa-dependent Notch func ...... -embryonic hematopoietic cells
@ast
RBPjkappa-dependent Notch func ...... -embryonic hematopoietic cells
@en
RBPjkappa-dependent Notch func ...... -embryonic hematopoietic cells
@nl
prefLabel
RBPjkappa-dependent Notch func ...... -embryonic hematopoietic cells
@ast
RBPjkappa-dependent Notch func ...... -embryonic hematopoietic cells
@en
RBPjkappa-dependent Notch func ...... -embryonic hematopoietic cells
@nl
P3181
P356
P1433
P1476
RBPjkappa-dependent Notch func ...... -embryonic hematopoietic cells
@en
P2093
Alex Robert-Moreno
Lluís Espinosa
P304
P3181
P356
10.1242/DEV.01660
P407
P577
2005-02-02T00:00:00Z