Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling
about
TULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary ciliaIns and outs of GPCR signaling in primary ciliaPrimary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengersInositol polyphosphate 5-phosphatases; new players in the regulation of cilia and ciliopathiesZfp423 Regulates Sonic Hedgehog Signaling via Primary Cilium FunctionExome sequencing identifies WDR35 variants involved in Sensenbrenner syndromeIntraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway componentsThe IFT-A complex regulates Shh signaling through cilia structure and membrane protein traffickingGata6-Dependent GLI3 Repressor Function is Essential in Anterior Limb Progenitor Cells for Proper Limb DevelopmentArl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteinsTubby is required for trafficking G protein-coupled receptors to neuronal ciliaThe tubby family proteins.Trafficking to the primary cilium membrane.Analysis of hedgehog signaling in mouse intraflagellar transport mutantsMIM and cortactin antagonism regulates ciliogenesis and hedgehog signaling.The heterotrimeric kinesin-2 complex interacts with and regulates GLI protein function.Pleiotropic patterning response to activation of Shh signaling in the limb apical ectodermal ridgeScoring a backstage pass: mechanisms of ciliogenesis and ciliary access.Endocytic recycling protein EHD1 regulates primary cilia morphogenesis and SHH signaling during neural tube development.The relationship between sonic Hedgehog signaling, cilia, and neural tube defectsIntraflagellar transport-A complex mediates ciliary entry and retrograde trafficking of ciliary G protein-coupled receptors.The primary cilium as a Hedgehog signal transduction machine.Primary cilia and graded Sonic Hedgehog signaling.G-protein-coupled receptors, Hedgehog signaling and primary cilia.Tubby family proteins are adapters for ciliary trafficking of integral membrane proteinsThe primary cilium as a cellular receiver: organizing ciliary GPCR signalingPrimary Cilia and Mammalian Hedgehog Signaling.Kinetics of hedgehog-dependent full-length Gli3 accumulation in primary cilia and subsequent degradation.Cilia, tubby mice, and obesityVariable expressivity of ciliopathy neurological phenotypes that encompass Meckel-Gruber syndrome and Joubert syndrome is caused by complex de-regulated ciliogenesis, Shh and Wnt signalling defects.The emerging roles of phosphatases in Hedgehog pathway.Phosphoinositides Regulate Ciliary Protein Trafficking to Modulate Hedgehog Signaling.What are those cilia doing in the neural tube?Lipid metabolism fattens up hedgehog signaling.The G protein-coupled receptor Gpr161 regulates forelimb formation, limb patterning and skeletal morphogenesis in a primary cilium-dependent manner.TULP3 is required for GPR161 localization in the ciliumG-protein-coupled receptors and localized signaling in the primary cilium during ventral neural tube patterning.BBSome trains remove activated GPCRs from cilia by enabling passage through the transition zone.Sending mixed signals: Cilia-dependent signaling during development and disease.Chronophin regulates active vitamin B6 levels and transcriptomic features of glioblastoma cell lines cultured under non-adherent, serum-free conditions.
P2860
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P248
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P2860
Tubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signaling
description
2009 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Mai 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/05/15)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/05/15)
@nl
наукова стаття, опублікована в травні 2009
@uk
مقالة علمية (نشرت في 15-5-2009)
@ar
name
Tubby-like protein 3 (TULP3) r ...... hibition of Hedgehog signaling
@ast
Tubby-like protein 3 (TULP3) r ...... hibition of Hedgehog signaling
@en
Tubby-like protein 3 (TULP3) r ...... hibition of Hedgehog signaling
@nl
type
label
Tubby-like protein 3 (TULP3) r ...... hibition of Hedgehog signaling
@ast
Tubby-like protein 3 (TULP3) r ...... hibition of Hedgehog signaling
@en
Tubby-like protein 3 (TULP3) r ...... hibition of Hedgehog signaling
@nl
prefLabel
Tubby-like protein 3 (TULP3) r ...... hibition of Hedgehog signaling
@ast
Tubby-like protein 3 (TULP3) r ...... hibition of Hedgehog signaling
@en
Tubby-like protein 3 (TULP3) r ...... hibition of Hedgehog signaling
@nl
P2093
P2860
P921
P3181
P356
P1476
Tubby-like protein 3 (TULP3) r ...... hibition of Hedgehog signaling
@en
P2093
Christine M. Eun
Hyuk W. Ko
Jonathan T. Eggenschwiler
Lisa L. Abler
Ryan X. Norman
Viola Huang
Zhen Zhang
P2860
P304
P3181
P356
10.1093/HMG/DDP113
P577
2009-05-15T00:00:00Z