Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis
about
Embryonic stem cells and somatic cells differ in mutation frequency and typePivotal role of Toll-like receptors 2 and 4, its adaptor molecule MyD88, and inflammasome complex in experimental tubule-interstitial nephritisMlh1 mediates tissue-specific regulation of mitotic recombinationMarked aneuploidy and loss of multiple chromosomes are common in autosomal mutants isolated from normal mouse kidney epithelium.Spontaneous mitotic homologous recombination at an enhanced yellow fluorescent protein (EYFP) cDNA direct repeat in transgenic mice.Bladder outlet obstruction in male cystinuria mice2,8-dihydroxyadenine nephrolithiasis induces developmental stage-specific alterations in gene expression in mouse kidneyMouse models for induced genetic instability at endogenous loci.Mitotic recombination produces the majority of recessive fibroblast variants in heterozygous mice.Altered hematopoiesis, behavior, and sexual function in mu opioid receptor-deficient miceRole of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations.Carcinogen-induced loss of heterozygosity at the Aprt locus in somatic cells of the mouseIonizing radiation is a potent inducer of mitotic recombination in mouse embryonic stem cells.Cancer Immunotherapy: Whence and Whither.Loss of heterozygosity or: how I learned to stop worrying and love mitotic recombination.Development of a novel mouse tk+/- embryonic stem cell line for use in mutagenicity studies.Administration of α-Galactosylceramide Improves Adenine-Induced Renal InjuryMacrophage trafficking as key mediator of adenine-induced kidney injury.In-silico gene essentiality analysis of polyamine biosynthesis reveals APRT as a potential target in cancer.Gender- and age-dependent changes in kidney androgen protein mRNA expression in a knockout mouse model for nephrolithiasis.Adenine phosphoribosyltransferase deficiency in children.Severe hyperparathyroidism with bone abnormalities and metastatic calcification in rats with adenine-induced uraemia.Human adipose derived stem cells regress fibrosis in a chronic renal fibrotic model induced by adenine.Age-related accumulation of autosomal mutations in solid tissues of the mouse is gender and cell type specific.Fish Oil Supplementation Reduces Inflammation but Does Not Restore Renal Function and Klotho Expression in an Adenine-Induced CKD Model
P2860
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P2860
Adenine phosphoribosyltransferase-deficient mice develop 2,8-dihydroxyadenine nephrolithiasis
description
1996 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մայիսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 1996
@ast
im Mai 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/05/28)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/05/28)
@nl
наукова стаття, опублікована в травні 1996
@uk
name
Adenine phosphoribosyltransfer ...... hydroxyadenine nephrolithiasis
@ast
Adenine phosphoribosyltransfer ...... hydroxyadenine nephrolithiasis
@en
Adenine phosphoribosyltransfer ...... hydroxyadenine nephrolithiasis
@nl
type
label
Adenine phosphoribosyltransfer ...... hydroxyadenine nephrolithiasis
@ast
Adenine phosphoribosyltransfer ...... hydroxyadenine nephrolithiasis
@en
Adenine phosphoribosyltransfer ...... hydroxyadenine nephrolithiasis
@nl
prefLabel
Adenine phosphoribosyltransfer ...... hydroxyadenine nephrolithiasis
@ast
Adenine phosphoribosyltransfer ...... hydroxyadenine nephrolithiasis
@en
Adenine phosphoribosyltransfer ...... hydroxyadenine nephrolithiasis
@nl
P2093
P2860
P356
P1476
Adenine phosphoribosyltransfer ...... hydroxyadenine nephrolithiasis
@en
P2093
H. A. Simmonds
J. A. Tischfield
M. G. Stockelman
M. Y. Ying
P. J. Stambrook
P. M. Davies
P2860
P304
P356
10.1073/PNAS.93.11.5307
P407
P577
1996-05-28T00:00:00Z