Mlh1 mediates tissue-specific regulation of mitotic recombination

Mlh1 mediates tissue-specific regulation of mitotic recombination

Item
http://www.wikidata.org/entity/Q28586588
MutS homologue hMSH4: interaction with eIF3f and a role in NHEJ-mediated DSB repairHuman MLH1 suppresses the insertion of telomeric sequences at intra-chromosomal sites in telomerase-expressing cells.Embryonic lethality after combined inactivation of Fancd2 and Mlh1 in mice.The frequency and structure of recombinant products is determined by the cellular level of MutL.Prdx1 deficiency in mice promotes tissue specific loss of heterozygosity mediated by deficiency in DNA repair and increased oxidative stress.Assessment of anti-recombination and double-strand break-induced gene conversion in human cells by a chromosomal reporter.CCR2-dependent recruitment of macrophages by tumor-educated mesenchymal stromal cells promotes tumor development and is mimicked by TNFαRole of the mismatch repair gene, Msh6, in suppressing genome instability and radiation-induced mutations.Mutagenesis in vivo in T cells of p21-deficient mice.Loss of MLH1 sensitizes colon cancer cells to DNA-PKcs inhibitor KU60648.Human MutL-complexes monitor homologous recombination independently of mismatch repair.The spectra of large second-step mutations are similar for two different mouse autosomes
P2860

Mlh1 mediates tissue-specific regulation of mitotic recombination

Item
http://www.wikidata.org/entity/Q28586588
description
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Dezember 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/12/02)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/12/02)
@nl
наукова стаття, опублікована в грудні 2004
@uk
مقالة علمية (نشرت في 2-12-2004)
@ar
name
Mlh1 mediates tissue-specific regulation of mitotic recombination
@ast
Mlh1 mediates tissue-specific regulation of mitotic recombination
@en
Mlh1 mediates tissue-specific regulation of mitotic recombination
@nl
type
label
Mlh1 mediates tissue-specific regulation of mitotic recombination
@ast
Mlh1 mediates tissue-specific regulation of mitotic recombination
@en
Mlh1 mediates tissue-specific regulation of mitotic recombination
@nl
prefLabel
Mlh1 mediates tissue-specific regulation of mitotic recombination
@ast
Mlh1 mediates tissue-specific regulation of mitotic recombination
@en
Mlh1 mediates tissue-specific regulation of mitotic recombination
@nl
P1433
P1476
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P6179
P698
P921
P356
P1433
P1476
Mlh1 mediates tissue-specific regulation of mitotic recombination
@en
P2093
P2860
P2888
P304
P31
P356
P407
P433
P478
P50
P577
P5875
P6179
P698
P921