Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity
about
Comparative analysis of viral RNA signatures on different RIG-I-like receptorsViral Polymerase-Helicase Complexes Regulate Replication Fidelity To Overcome Intracellular Nucleotide DepletionEmerging Roles of Protein Deamidation in Innate Immune SignalingIdentification of a small molecule that primes the type I interferon response to cytosolic DNA.Novel indole-2-carboxamide compounds are potent broad-spectrum antivirals active against western equine encephalitis virus in vivo.[Stimulation of the antiviral innate immune response by pyrimidine biosynthesis inhibitors: a surprise of phenotypic screening].Redoxal, an inhibitor of de novo pyrimidine biosynthesis, augments APOBEC3G antiviral activity against human immunodeficiency virus type 1.Replication-Competent Influenza Virus and Respiratory Syncytial Virus Luciferase Reporter Strains Engineered for Co-Infections Identify Antiviral Compounds in Combination Screens.Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH)Emodin potentiates the antiproliferative effect of interferon α/β by activation of JAK/STAT pathway signaling through inhibition of the 26S proteasomeCross Talk between Nucleotide Synthesis Pathways with Cellular Immunity in Constraining Hepatitis E Virus Replication.Dietary apigenin potentiates the inhibitory effect of interferon-α on cancer cell viability through inhibition of 26S proteasome-mediated interferon receptor degradationAn efficient method for gene silencing in human primary plasmacytoid dendritic cells: silencing of the TLR7/IRF-7 pathway as a proof of concept.Inhibition of arenavirus by A3, a pyrimidine biosynthesis inhibitor.Interferon regulatory factor-1 (IRF-1) protects against chikungunya virus induced immunopathology by restricting infection in muscle cells.Original Chemical Series of Pyrimidine Biosynthesis Inhibitors That Boost the Antiviral Interferon Response.Discovery of a Broad-Spectrum Antiviral Compound That Inhibits Pyrimidine Biosynthesis and Establishes a Type 1 Interferon-Independent Antiviral State.[Stimulating Type I interferon response with small molecules: revival of an old idea].Therapeutic Approaches for Zika Virus Infection of the Nervous System.A compendium of small molecule direct-acting and host-targeting inhibitors as therapies against alphaviruses.The Establishment of an Antiviral State by Pyrimidine Synthesis Inhibitor is Cell Type-Specific.Characterization of an influenza virus pseudotyped with Ebolavirus glycoprotein.A DHODH inhibitor increases p53 synthesis and enhances tumor cell killing by p53 degradation blockage.Gemcitabine and Nucleos(t)ide Synthesis Inhibitors Are Broad-Spectrum Antiviral Drugs that Activate Innate Immunity.A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle
P2860
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P2860
Inhibition of pyrimidine biosynthesis pathway suppresses viral growth through innate immunity
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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name
Inhibition of pyrimidine biosy ...... growth through innate immunity
@ast
Inhibition of pyrimidine biosy ...... growth through innate immunity
@en
Inhibition of pyrimidine biosy ...... growth through innate immunity
@nl
type
label
Inhibition of pyrimidine biosy ...... growth through innate immunity
@ast
Inhibition of pyrimidine biosy ...... growth through innate immunity
@en
Inhibition of pyrimidine biosy ...... growth through innate immunity
@nl
prefLabel
Inhibition of pyrimidine biosy ...... growth through innate immunity
@ast
Inhibition of pyrimidine biosy ...... growth through innate immunity
@en
Inhibition of pyrimidine biosy ...... growth through innate immunity
@nl
P2093
P2860
P50
P3181
P1433
P1476
Inhibition of pyrimidine biosy ...... growth through innate immunity
@en
P2093
Daniel Dauzonne
Gaëlle Cousin
Geneviève Janvier
Grégory Caignard
Gwénaëlle André-Leroux
Marianne Lucas-Hourani
Nicolas Escriou
Olivier Helynck
Pierre Jorda
Samira Khiar
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1003678
P407
P50
P577
2013-01-01T00:00:00Z