Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

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Aptamer and its applications in neurodegenerative diseases.Nucleic Acid Aptamers: Emerging Applications in Medical Imaging, Nanotechnology, Neurosciences, and Drug Delivery.Nucleic Acid-Based Theranostics for Tackling Alzheimer's Disease.

P2860

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P2860

Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

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http://www.wikidata.org/entity/Q28550356

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2015 nî lūn-bûn

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2015 թուականին հրատարակուած գիտական յօդուած

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2015 թվականին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

@ast

Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

@en

Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

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type

Item

label

Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

@ast

Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

@en

Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

@nl

prefLabel

Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

@ast

Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

@en

Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

@nl

P1476

Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

@en

P2093

Fang Wang

http://www.w3.org/2001/XMLSchema#string

Huiyu Liang

http://www.w3.org/2001/XMLSchema#string

Shuji Li

http://www.w3.org/2001/XMLSchema#string

Wenjun Chen

http://www.w3.org/2001/XMLSchema#string

Xiaowen Li

http://www.w3.org/2001/XMLSchema#string

Ying Wang

http://www.w3.org/2001/XMLSchema#string

Yonghua Peng

http://www.w3.org/2001/XMLSchema#string

Yusheng Shi

http://www.w3.org/2001/XMLSchema#string

Zhewen Kou

http://www.w3.org/2001/XMLSchema#string

P2860

Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE

A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline

Alzheimer mechanisms and therapeutic strategies

Multifunctional nanoparticles for brain tumor imaging and therapy.

Design and synthesis of aminohydantoins as potent and selective human β-secretase (BACE1) inhibitors with enhanced brain permeability

Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer Disease

Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations

Differential SELEX in human glioma cell lines

Aptamers and their biological applications

Identification of an aptamer targeting hnRNP A1 by tissue slide-based SELEX.

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e0140733

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scholarly article

P356

10.1371/JOURNAL.PONE.0140733

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P407

English

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http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

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Xing-Mei Zhang

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2015-10-16T00:00:00Z

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282913119

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26473367

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P921

Alzheimer's disease

P932

4608735

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Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

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P2860

P2860

Inhibition of BACE1 Activity by a DNA Aptamer in an Alzheimer's Disease Cell Model

description

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type

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P1433

P1476

P2093

P2860

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P932