The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
about
RAD51 as a potential surrogate marker for DNA repair capacity in solid malignancies.The NEIL1 G83D germline DNA glycosylase variant induces genomic instability and cellular transformation.A cell-penetrating antibody inhibits human RAD51 via direct binding.Defects in recombination activity caused by somatic and germline mutations in the multimerization/BRCA2 binding region of human RAD51 protein.Unresolved recombination intermediates lead to ultra-fine anaphase bridges, chromosome breaks and aberrations.Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state.Distinct roles of ATM and ATR in the regulation of ARP8 phosphorylation to prevent chromosome translocations.Variation in RAD51 details a hub of functions: opportunities to advance cancer diagnosis and therapyMelatonin Sensitizes Hepatocellular Carcinoma Cells to Chemotherapy Through Long Non-Coding RNA RAD51-AS1-Mediated Suppression of DNA Repair
P2860
Q38801052-6914E53C-0FB8-4254-BB8D-58C7E5E0DCF1Q47100233-31824361-6F56-4ADF-9457-96DC8E9B1FBAQ47138403-8068C814-D788-4398-A7D4-1A97350FF4C6Q47445010-0D7ACA1C-F41C-4599-B092-5DE25D2B8B99Q48097725-A1D24398-34F3-4482-A9D7-3D17362804A4Q50421855-88815EA9-6DDB-4AC7-95E8-F3BED08E29C8Q55001708-4D871A35-4AE2-4A33-947F-67AD17F90C03Q57112352-B8ABEFEA-3108-474A-9717-8C54D466A343Q58753461-48E1BC2F-B1D6-46B7-AF48-C35CC5313C68
P2860
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
description
2016 nî lūn-bûn
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2016 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
@ast
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
@en
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
@nl
type
label
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
@ast
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
@en
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
@nl
prefLabel
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
@ast
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
@en
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
@nl
P2093
P2860
P3181
P1433
P1476
The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype
@en
P2093
Carolyn G Marsden
Jennifer Zagelbaum
Joann B Sweasy
Ryan B Jensen
Scott W Morrical
Susan S Wallace
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1006208
P407
P577
2016-08-11T00:00:00Z