RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments - Test2 - elhamkhani - TriplyDB

RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments

RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments

http://www.wikidata.org/entity/Q24676019

about

Unwinding and rewinding: double faces of helicase?RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progression Structural mimicry in transcription regulation of human RNA polymerase II by the DNA helicase RECQL5 Human RECQL5 participates in the removal of endogenous DNA damage Inhibition of homologous recombination by the PCNA-interacting protein PARI CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1 Rad51 paralog complexes BCDX2 and CX3 act at different stages in the BRCA1-BRCA2-dependent homologous recombination pathway RTEL1 maintains genomic stability by suppressing homologous recombination Human Fbh1 helicase contributes to genome maintenance via pro- and anti-recombinase activities FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51 FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells The RecQ DNA helicases in DNA repair The Werner syndrome protein: linking the replication checkpoint response to genome stability Human RECQ helicases: roles in DNA metabolism, mutagenesis and cancer biology Roles of RECQ helicases in recombination based DNA repair, genomic stability and aging More complexity to the Bloom's syndrome complex BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome Connecting the Dots: From DNA Damage and Repair to Aging Close encounters for the first time: Helicase interactions with DNA damage Roles of DNA helicases in the maintenance of genome integrity RecQ helicases in DNA double strand break repair and telomere maintenance.Yeast Mph1 helicase dissociates Rad51-made D-loops: implications for crossover control in mitotic recombination.Remodeling of the Rad51 DNA strand-exchange protein by the Srs2 helicase.Srs2 disassembles Rad51 filaments by a protein-protein interaction triggering ATP turnover and dissociation of Rad51 from DNA.DNA Polymerase θ: A Unique Multifunctional End-Joining Machine RAD51 mutants cause replication defects and chromosomal instability The consequences of Rad51 overexpression for normal and tumor cells Characterization of human Spartan/C1orf124, an ubiquitin-PCNA interacting regulator of DNA damage tolerance Cooperation of breast cancer proteins PALB2 and piccolo BRCA2 in stimulating homologous recombination From yeast to mammals: recent advances in genetic control of homologous recombination The Werner syndrome helicase/exonuclease processes mobile D-loops through branch migration and degradation RECQL5 and BLM exhibit divergent functions in cells defective for the Fanconi anemia pathway The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype Essential roles of BCCIP in mouse embryonic development and structural stability of chromosomes RNA Polymerase II C-Terminal Domain: Tethering Transcription to Transcript and Template Novel pro- and anti-recombination activities of the Bloom's syndrome helicase.The role of the Fanconi anemia network in the response to DNA replication stress.Replication protein A stimulates the Werner syndrome protein branch migration activity.Sgs1 and exo1 redundantly inhibit break-induced replication and de novo telomere addition at broken chromosome ends.Biochemistry of Meiotic Recombination: Formation, Processing, and Resolution of Recombination Intermediates.

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P2860

RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments

http://www.wikidata.org/entity/Q24676019

description

2007 nî lūn-bûn

@nan

2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2007年の論文

@ja

2007年論文

@yue

2007年論文

@zh-hant

2007年論文

@zh-hk

2007年論文

@zh-mo

2007年論文

@zh-tw

2007年论文

@wuu

name

RECQL5/Recql5 helicase regulat ...... of Rad51 presynaptic filaments

@ast

RECQL5/Recql5 helicase regulat ...... of Rad51 presynaptic filaments

@en

RECQL5/Recql5 helicase regulat ...... of Rad51 presynaptic filaments

@nl

type

label

RECQL5/Recql5 helicase regulat ...... of Rad51 presynaptic filaments

@ast

RECQL5/Recql5 helicase regulat ...... of Rad51 presynaptic filaments

@en

RECQL5/Recql5 helicase regulat ...... of Rad51 presynaptic filaments

@nl

prefLabel

RECQL5/Recql5 helicase regulat ...... of Rad51 presynaptic filaments

@ast

RECQL5/Recql5 helicase regulat ...... of Rad51 presynaptic filaments

@en

RECQL5/Recql5 helicase regulat ...... of Rad51 presynaptic filaments

@nl

P1433

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P1476

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P2860

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P304

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P31

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P3181

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P356

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P407

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P5875

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P932

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P3181

P356

P1433

Genes & Development

P1476

RECQL5/Recql5 helicase regulat ...... of Rad51 presynaptic filaments

@en

P2093

Ellen L Barnes

http://www.w3.org/2001/XMLSchema#string

Guangbin Luo

http://www.w3.org/2001/XMLSchema#string

Hannes Vogel

http://www.w3.org/2001/XMLSchema#string

Jeremy M Stark

http://www.w3.org/2001/XMLSchema#string

Lu Zheng

http://www.w3.org/2001/XMLSchema#string

Michael G Sehorn

http://www.w3.org/2001/XMLSchema#string

Patrick Sung

http://www.w3.org/2001/XMLSchema#string

Pavel Janscak

http://www.w3.org/2001/XMLSchema#string

Peter Chi

http://www.w3.org/2001/XMLSchema#string

Steven Raynard

http://www.w3.org/2001/XMLSchema#string

P2860

Human RecQ5beta, a large isomer of RecQ5 DNA helicase, localizes in the nucleoplasm and interacts with topoisomerases 3alpha and 3beta.

The Bloom's syndrome gene product is homologous to RecQ helicases

Recql5 and Blm RecQ DNA helicases have nonredundant roles in suppressing crossovers.

BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates

Multiple pathways of recombination induced by double-strand breaks in Saccharomyces cerevisiae

Human RECQ5beta, a protein with DNA helicase and strand-annealing activities in a single polypeptide

Human RECQ5beta helicase promotes strand exchange on synthetic DNA structures resembling a stalled replication fork

Genetic control of intrachromosomal recombination in Saccharomyces cerevisiae. I. Isolation and genetic characterization of hyper-recombination mutations.

The Srs2 helicase prevents recombination by disrupting Rad51 nucleoprotein filaments.

Yeast Rmi1/Nce4 controls genome stability as a subunit of the Sgs1-Top3 complex.

P304

3073-84

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

1803209

http://www.w3.org/2001/XMLSchema#string

P356

10.1101/GAD.1609107

http://www.w3.org/2001/XMLSchema#string

P407

P433

23

http://www.w3.org/2001/XMLSchema#string

P478

21

http://www.w3.org/2001/XMLSchema#string

P50

P577

2007-12-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

5842879

http://www.w3.org/2001/XMLSchema#string

P698

18003859

http://www.w3.org/2001/XMLSchema#string

P932

2081974

http://www.w3.org/2001/XMLSchema#string