FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells
about
FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51Remodeling and Control of Homologous Recombination by DNA Helicases and Translocases that Target Recombinases and SynapsisLarge-scale genomic analyses link reproductive aging to hypothalamic signaling, breast cancer susceptibility and BRCA1-mediated DNA repairThe Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination PhenotypeArtesunate sensitizes ovarian cancer cells to cisplatin by downregulating RAD51.Novel function of the Fanconi anemia group J or RECQ1 helicase to disrupt protein-DNA complexes in a replication protein A-stimulated manner.Rad51/Dmc1 paralogs and mediators oppose DNA helicases to limit hybrid DNA formation and promote crossovers during meiotic recombinationCell biology of mitotic recombination.Multiple regulation of Rad51-mediated homologous recombination by fission yeast Fbh1.It is not all about BRCA: Cullin-Ring ubiquitin Ligases in ovarian cancer.The MMS22L-TONSL heterodimer directly promotes RAD51-dependent recombination upon replication stress.The PCNA-associated protein PARI negatively regulates homologous recombination via the inhibition of DNA repair synthesis.Repair Pathway Choices and Consequences at the Double-Strand BreakHuman RECQ5 helicase promotes repair of DNA double-strand breaks by synthesis-dependent strand annealing.Regulation of recombination and genomic maintenance.An Overview of the Molecular Mechanisms of Recombinational DNA Repair.DNA replication stress: from molecular mechanisms to human disease.WRNIP1 protects stalled forks from degradation and promotes fork restart after replication stress.Multifunctional roles of Saccharomyces cerevisiae Srs2 protein in replication, recombination and repair.Dissociation of Rad51 Presynaptic Complexes and Heteroduplex DNA Joints by Tandem Assemblies of Srs2.BLM helicase regulates DNA repair by counteracting RAD51 loading at DNA double-strand break sites.PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation.Human RAD51 rapidly forms intrinsically dynamic nucleoprotein filaments modulated by nucleotide binding state.
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P2860
FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells
description
2013 nî lūn-bûn
@nan
2013 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@ast
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@en
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@en-gb
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@nl
type
label
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@ast
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@en
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@en-gb
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@nl
prefLabel
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@ast
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@en
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@en-gb
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
FBH1 helicase disrupts RAD51 f ...... combination in mammalian cells
@en
P2093
Dylan A Reid
Ian D Hickson
Igor Shevelev
Jennifer Zagelbaum
Jitka Simandlova
Pavel Janscak
Sujoy Chatterjee
Wai Kit Chu
P2860
P304
34168-34180
P3181
P356
10.1074/JBC.M113.484493
P407
P577
2013-10-09T00:00:00Z