Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation - Test2 - elhamkhani - TriplyDB

Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation

Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation

http://www.wikidata.org/entity/Q28568275

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mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide Essential function of TORC2 in PKC and Akt turn motif phosphorylation, maturation and signalling Protein kinases and phosphatases in the control of cell fate Regulation of protein kinase C inactivation by Fas-associated protein with death domain Characterization of Rictor phosphorylation sites reveals direct regulation of mTOR complex 2 by S6K1 Biallelic Mutations in Citron Kinase Link Mitotic Cytokinesis to Human Primary Microcephaly Targeting Protein Kinase C Downstream of Growth Factor and Adhesion Signalling Structural Diversity of the Active N-Terminal Kinase Domain of p90 Ribosomal S6 Kinase 2 Activation of G Protein-Coupled Receptor Kinase 1 Involves Interactions between Its N-Terminal Region and Its Kinase Domain A Novel Locus Harbouring a Functional CD164 Nonsense Mutation Identified in a Large Danish Family with Nonsyndromic Hearing Impairment Protein kinase C: poised to signal The mammalian target of rapamycin complex 2 controls folding and stability of Akt and protein kinase C Bacterial Expression, Purification and In Vitro Phosphorylation of Full-Length Ribosomal S6 Kinase 2 (RSK2)The unusual mechanism of inhibition of the p90 ribosomal S6 kinase (RSK) by flavonol rhamnosides.Yersinia virulence factor YopM induces sustained RSK activation by interfering with dephosphorylation.Conserved modular domains team up to latch-open active protein kinase Cα Toward defining the phosphoproteome of Xenopus laevis embryos.Crystal structures of PRK1 in complex with the clinical compounds lestaurtinib and tofacitinib reveal ligand induced conformational changes.A novel pleckstrin homology domain-containing protein enhances insulin-stimulated Akt phosphorylation and GLUT4 translocation in adipocytes.Hydrophobic motif phosphorylation is not required for activation loop phosphorylation of p70 ribosomal protein S6 kinase 1 (S6K1).mTOR complex 2 signaling and functions Peptidyl-prolyl isomerase Pin1 controls down-regulation of conventional protein kinase C isozymes Cotranslational cis-phosphorylation of the COOH-terminal tail is a key priming step in the maturation of cAMP-dependent protein kinase Protein kinase Cζ exhibits constitutive phosphorylation and phosphatidylinositol-3,4,5-triphosphate-independent regulation Regulation of a third conserved phosphorylation site in SGK1 A surface of the kinase domain critical for the allosteric activation of G protein-coupled receptor kinases.Mutation of the 3-phosphoinositide-dependent protein kinase-1 (PDK1) substrate-docking site in the developing brain causes microcephaly with abnormal brain morphogenesis independently of Akt, leading to impaired cognition and disruptive behaviors.3-D structure and dynamics of protein kinase B-new mechanism for the allosteric regulation of an AGC kinase.Mammalian TOR signaling to the AGC kinases.The protein kinase C super-family member PKN is regulated by mTOR and influences differentiation during prostate cancer progression.Determinants for activation of the atypical AGC kinase Greatwall during M phase entry.mTORC2 targets AGC kinases through Sin1-dependent recruitment.Intramolecular conformational changes optimize protein kinase C signaling.Regulation of the interaction between protein kinase C-related protein kinase 2 (PRK2) and its upstream kinase, 3-phosphoinositide-dependent protein kinase 1 (PDK1).A chimeric mechanism for polyvalent trans-phosphorylation of PKA by PDK1.The Stress-Sensing TORC2 Complex Activates Yeast AGC-Family Protein Kinase Ypk1 at Multiple Novel Sites.The TORC2-Dependent Signaling Network in the Yeast Saccharomyces cerevisiae.Regulation of protein kinase C-related protein kinase 2 (PRK2) by an intermolecular PRK2-PRK2 interaction mediated by Its N-terminal domain.Allosteric inhibition of Aurora-A kinase by a synthetic vNAR domain.Characterization of the mechanisms controlling Greatwall activity.

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P2860

Mechanism for activation of the growth factor-activated AGC kinases by turn motif phosphorylation

http://www.wikidata.org/entity/Q28568275

description

2007 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի մայիսին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2007

@ast

im Mai 2007 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2007/05/02)

@sk

vědecký článek publikovaný v roce 2007

@cs

wetenschappelijk artikel (gepubliceerd op 2007/05/02)

@nl

наукова стаття, опублікована в травні 2007

@uk

مقالة علمية (نشرت في 2-5-2007)

@ar

name

Mechanism for activation of th ...... by turn motif phosphorylation

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Mechanism for activation of th ...... by turn motif phosphorylation

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Mechanism for activation of th ...... by turn motif phosphorylation

@nl

type

label

Mechanism for activation of th ...... by turn motif phosphorylation

@ast

Mechanism for activation of th ...... by turn motif phosphorylation

@en

Mechanism for activation of th ...... by turn motif phosphorylation

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prefLabel

Mechanism for activation of th ...... by turn motif phosphorylation

@ast

Mechanism for activation of th ...... by turn motif phosphorylation

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Mechanism for activation of th ...... by turn motif phosphorylation

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SJ.EMBOJ.7601682

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The EMBO Journal

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Mechanism for activation of th ...... by turn motif phosphorylation

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P2093

Camilla Hauge

http://www.w3.org/2001/XMLSchema#string

Daniel Hirschberg

http://www.w3.org/2001/XMLSchema#string

Katrine Thorup

http://www.w3.org/2001/XMLSchema#string

Torben L Antal

http://www.w3.org/2001/XMLSchema#string

Ulrik Doehn

http://www.w3.org/2001/XMLSchema#string

P2860

Characterization of the structure and regulation of two novel isoforms of serum- and glucocorticoid-induced protein kinase

Mechanism of activation of protein kinase B by insulin and IGF-1

Allosteric activation of the protein kinase PDK1 with low molecular weight compounds

Crystal structure of an activated Akt/protein kinase B ternary complex with GSK3-peptide and AMP-PNP

A phosphoserine/threonine-binding pocket in AGC kinases and PDK1 mediates activation by hydrophobic motif phosphorylation.

Identification of a pocket in the PDK1 kinase domain that interacts with PIF and the C-terminal residues of PKA

Dual requirement for a newly identified phosphorylation site in p70s6k

Molecular mechanism for the regulation of protein kinase B/Akt by hydrophobic motif phosphorylation

High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site.

Crystal structure of the catalytic subunit of cyclic adenosine monophosphate-dependent protein kinase

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2251-2261

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3024034

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10.1038/SJ.EMBOJ.7601682

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9

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26

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Ricardo M Biondi

Thomas J.D. Jørgensen

Leila Idrissova

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2007-04-19T00:00:00Z

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6381668

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17446865

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phosphorylation

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1864980

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