Pax6 is crucial for β-cell function, insulin biosynthesis, and glucose-induced insulin secretion
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Long Noncoding RNAs in Metabolic Syndrome Related DisordersThe transcription factor Pax6 is required for pancreatic β cell identity, glucose-regulated ATP synthesis, and Ca2+ dynamics in adult miceLong-term supranutritional supplementation with selenate decreases hyperglycemia and promotes fatty liver degeneration by inducing hyperinsulinemia in diabetic db/db mice.Global genomic and transcriptomic analysis of human pancreatic islets reveals novel genes influencing glucose metabolismPax6 directly down-regulates Pcsk1n expression thereby regulating PC1/3 dependent proinsulin processing.The developmental regulator Pax6 is essential for maintenance of islet cell function in the adult mouse pancreasChronic exposure to GLP-1 increases GLP-1 synthesis and release in a pancreatic alpha cell line (α-TC1): evidence of a direct effect of GLP-1 on pancreatic alpha cellsHigh-fat diet induced insulin resistance in pregnant rats through pancreatic pax6 signaling pathway.Pax6 Inactivation in the Adult Pancreas Reveals Ghrelin as Endocrine Cell Maturation MarkerThe circular RNA Cdr1as, via miR-7 and its targets, regulates insulin transcription and secretion in islet cells.Characterization of Antibodies to Products of Proinsulin Processing Using Immunofluorescence Staining of Pancreas in Multiple Species.Evidence of stress in β cells obtained with laser capture microdissection from pancreases of brain dead donors.In Vivo Exposures to Particulate Matter Collected from Saudi Arabia or Nickel Chloride Display Similar Dysregulation of Metabolic Syndrome Genes.Deletion of retinoic acid receptor β (RARβ) impairs pancreatic endocrine differentiation.PAX6 maintains β cell identity by repressing genes of alternative islet cell types.Glucagon: the renewal of an old hormone in the pathophysiology of diabetes.Taurine supplementation ameliorates glucose homeostasis, prevents insulin and glucagon hypersecretion, and controls β, α, and δ-cell masses in genetic obese mice.Computational analyses of type 2 diabetes-associated loci identified by genome-wide association studies.The long non-coding RNA Paupar regulates the expression of both local and distal genes.Glucose-dependent downregulation of glucagon gene expression mediated by selective interactions between ALX3 and PAX6 in mouse alpha cells.PCSK1 Variants and Human Obesity.CCCTC-binding factor mediates effects of glucose on beta cell survival.Potential regulatory mechanisms of lncRNA in diabetes and its complications.Pancreatic differentiation of human dental pulp CD117⁺ stem cells.Reprogramming of Pancreatic Exocrine Cells AR42J Into Insulin-producing Cells Using mRNAs for Pdx1, Ngn3, and MafA Transcription Factors.Whole-transcriptome analysis of mouse adipose tissue in response to short-term caloric restriction.Microphthalmia transcription factor regulates pancreatic β-cell function.Intrauterine Reprogramming of the Polycystic Ovary Syndrome: Evidence from a Pilot Study of Cord Blood Global Methylation Analysis.The Role of Epigenetic Regulation and Pluripotency-Related MicroRNAs in Differentiation of Pancreatic Stem Cells to Beta Cells.Distinct roles for the mTOR pathway in postnatal morphogenesis, maturation and function of pancreatic islets.Circulating microRNAs in Diabetes Progression: Discovery, Validation, and Research Translation.Comparative Study of Liraglutide and Insulin Glargine on Glycemic Control and Pancreatic β-Cell Function in db/db Mice.Protecting Pax6 3' UTR from MicroRNA-7 Partially Restores PAX6 in Islets from an Aniridia Mouse ModelFunctional characteristics of novel pancreatic Pax6 regulatory elements
P2860
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P2860
Pax6 is crucial for β-cell function, insulin biosynthesis, and glucose-induced insulin secretion
description
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
@ast
im April 2012 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2012/04/01)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/04/01)
@nl
наукова стаття, опублікована у квітні 2012
@uk
مقالة علمية (نشرت في أبريل 2012)
@ar
name
Pax6 is crucial for β-cell fun ...... cose-induced insulin secretion
@ast
Pax6 is crucial for β-cell fun ...... cose-induced insulin secretion
@en
Pax6 is crucial for β-cell fun ...... cose-induced insulin secretion
@nl
type
label
Pax6 is crucial for β-cell fun ...... cose-induced insulin secretion
@ast
Pax6 is crucial for β-cell fun ...... cose-induced insulin secretion
@en
Pax6 is crucial for β-cell fun ...... cose-induced insulin secretion
@nl
prefLabel
Pax6 is crucial for β-cell fun ...... cose-induced insulin secretion
@ast
Pax6 is crucial for β-cell fun ...... cose-induced insulin secretion
@en
Pax6 is crucial for β-cell fun ...... cose-induced insulin secretion
@nl
P2093
P2860
P3181
P356
P1476
Pax6 is crucial for β-cell fun ...... cose-induced insulin secretion
@en
P2093
Caroline Poisson
Claire Cheyssac
Jacques Philippe
Liora S. Katz
Mounia Heddad Masson
Yvan Gosmain
P2860
P304
P3181
P356
10.1210/ME.2011-1256
P577
2012-04-01T00:00:00Z