A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure
about
The MEKK1 PHD ubiquitinates TAB1 to activate MAPKs in response to cytokinesThe development of a novel high throughput computational tool for studying individual and collective cellular migrationbFGF regulates PI3-kinase-Rac1-JNK pathway and promotes fibroblast migration in wound healingRole of TGFβ in regulation of the tumor microenvironment and drug delivery (review)TGFβ Signaling in Tumor Initiation, Epithelial-to-Mesenchymal Transition, and MetastasisA RING to rule them all? Insights into the Map3k1 PHD motif provide a new mechanistic understanding into the diverse roles of Map3k1Keratinocyte migration in the developing eyelid requires LIMK2Raf-1 sets the threshold of Fas sensitivity by modulating Rok-alpha signalingExcess biglycan causes eyelid malformation by perturbing muscle development and TGF-alpha signalingEpithelial sheet movement requires the cooperation of c-Jun and MAP3K1Serum response factor is essential for the proper development of skin epitheliumDeciphering gene expression program of MAP3K1 in mouse eyelid morphogenesisGene-Environment Interactions Target Mitogen-activated Protein 3 Kinase 1 (MAP3K1) Signaling in Eyelid MorphogenesisNon-Smad pathways in TGF-beta signalingMAP3K1 function is essential for cytoarchitecture of the mouse organ of Corti and survival of auditory hair cells.A complex containing LPP and α-actinin mediates TGFβ-induced migration and invasion of ErbB2-expressing breast cancer cells.Somatic excision demonstrates that c-Jun induces cellular migration and invasion through induction of stem cell factor.Leader cell positioning drives wound-directed collective migration in TGFβ-stimulated epithelial sheets.Mixed lineage kinase-3/JNK1 axis promotes migration of human gastric cancer cells following gastrin stimulation.Minor abnormalities of testis development in mice lacking the gene encoding the MAPK signalling component, MAP3K1.Activin B promotes epithelial wound healing in vivo through RhoA-JNK signaling pathway.Alteration of skin wound healing in keratinocyte-specific mediator complex subunit 1 null mice.JNK is a novel regulator of intercellular adhesionAnthrax lethal factor and edema factor act on conserved targets in Drosophila.The expression of Pax6 variants is subject to posttranscriptional regulation in the developing mouse eyelid.Eyelid closure in embryogenesis is required for ocular adnexa developmentA role for the mitogen-activated protein kinase kinase kinase 1 in epithelial wound healing.Newly developed TGF-β2 knock down transgenic mouse lines express TGF-β2 differently and its distribution in multiple tissues variesMitogen-activated protein kinase kinase kinase 1 (MAP3K1) integrates developmental signals for eyelid closureTGF-β signaling and its role in the regulation of hematopoietic stem cells.Role of JNK in mammary gland development and breast cancer.A novel allele of Alx4 results in reduced Fgf10 expression and failure of eyelid fusion in mice.Mitogen activated protein kinases as targets for development of novel anti-inflammatory drugsFunction of Wnt/β-catenin in counteracting Tcf3 repression through the Tcf3-β-catenin interactionInflammation-activated protein kinases as targets for drug developmentROCK-I regulates closure of the eyelids and ventral body wall by inducing assembly of actomyosin bundlesThe goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells.ADAM17 transactivates EGFR signaling during embryonic eyelid closure.Ectodermal Wnt controls nasal pit morphogenesis through modulation of the BMP/FGF/JNK signaling axis.The canonical Wnt signaling antagonist DKK2 is an essential effector of PITX2 function during normal eye development.
P2860
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P2860
A role for MEK kinase 1 in TGF-beta/activin-induced epithelium movement and embryonic eyelid closure
description
2003 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2003
@ast
im September 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2003/09/01)
@sk
vědecký článek publikovaný v roce 2003
@cs
wetenschappelijk artikel (gepubliceerd op 2003/09/01)
@nl
наукова стаття, опублікована у вересні 2003
@uk
مقالة علمية (نشرت في سبتمبر 2003)
@ar
name
A role for MEK kinase 1 in TGF ...... t and embryonic eyelid closure
@ast
A role for MEK kinase 1 in TGF ...... t and embryonic eyelid closure
@en
A role for MEK kinase 1 in TGF ...... t and embryonic eyelid closure
@nl
type
label
A role for MEK kinase 1 in TGF ...... t and embryonic eyelid closure
@ast
A role for MEK kinase 1 in TGF ...... t and embryonic eyelid closure
@en
A role for MEK kinase 1 in TGF ...... t and embryonic eyelid closure
@nl
prefLabel
A role for MEK kinase 1 in TGF ...... t and embryonic eyelid closure
@ast
A role for MEK kinase 1 in TGF ...... t and embryonic eyelid closure
@en
A role for MEK kinase 1 in TGF ...... t and embryonic eyelid closure
@nl
P2093
P2860
P356
P1433
P1476
A role for MEK kinase 1 in TGF ...... t and embryonic eyelid closure
@en
P2093
David E Birk
Michael Karin
Winston W-Y Kao
Yasuhito Hayashi
P2860
P304
P356
10.1093/EMBOJ/CDG440
P407
P577
2003-09-01T00:00:00Z