Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functions
about
Conserved linker regions and their regulation determine multiple chromatin-binding modes of UHRF1Global Transcriptome Analysis Reveals That Poly(ADP-Ribose) Polymerase 1 Regulates Gene Expression through EZH2.PARP1 regulates the protein stability and proapoptotic function of HIPK2.Histone-mediated epigenetics in addiction.Role of PARP-1 in prostate cancer.Therapeutic Targeting of Poly(ADP-Ribose) Polymerase-1 (PARP1) in Cancer: Current Developments, Therapeutic Strategies, and Future Opportunities.Poly(ADP-ribosyl)ation of Methyl CpG Binding Domain Protein 2 Regulates Chromatin Structure.Loss of Uhrf1 in neural stem cells leads to activation of retroviral elements and delayed neurodegeneration.5mC-hydroxylase activity is influenced by the PARylation of TET1 enzyme.DNMT1 mutations found in HSANIE patients affect interaction with UHRF1 and neuronal differentiation.Targeting the SET and RING-associated (SRA) domain of ubiquitin-like, PHD and ring finger-containing 1 (UHRF1) for anti-cancer drug development.PARP inhibitor veliparib and HDAC inhibitor SAHA synergistically co-target the UHRF1/BRCA1 DNA damage repair complex in prostate cancer cellsHuman proteins that interact with RNA/DNA hybridsRecruitment of ubiquitin-activating enzyme UBA1 to DNA by poly(ADP-ribose) promotes ATR signalling
P2860
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P2860
Poly(ADP-ribose) polymerase 1 (PARP1) associates with E3 ubiquitin-protein ligase UHRF1 and modulates UHRF1 biological functions
description
2014 nî lūn-bûn
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2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2014 թվականի ապրիլին հրատարակված գիտական հոդված
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2014年の論文
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2014年学术文章
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2014年学术文章
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name
Poly(ADP-ribose) polymerase 1 ...... tes UHRF1 biological functions
@ast
Poly(ADP-ribose) polymerase 1 ...... tes UHRF1 biological functions
@en
type
label
Poly(ADP-ribose) polymerase 1 ...... tes UHRF1 biological functions
@ast
Poly(ADP-ribose) polymerase 1 ...... tes UHRF1 biological functions
@en
prefLabel
Poly(ADP-ribose) polymerase 1 ...... tes UHRF1 biological functions
@ast
Poly(ADP-ribose) polymerase 1 ...... tes UHRF1 biological functions
@en
P2093
P2860
P356
P1476
Poly(ADP-ribose) polymerase 1 ...... tes UHRF1 biological functions
@en
P2093
Delphine Quénet
Federica Babbio
Heinrich Leonhardt
Ian Marc Bonapace
Mike De Vos
Najat Magroun
Patricia Wolf
Rosy El Ramy
Valérie Schreiber
P2860
P304
16223-16238
P356
10.1074/JBC.M113.527424
P407
P577
2014-04-29T00:00:00Z