Glutamine-specific N-terminal amidase, a component of the N-end rule pathway
about
The N-end rule pathwayMouse Dfa is a repressor of TATA-box promoters and interacts with the Abt1 activator of basal transcriptionStructural basis for the recognition of N-end rule substrates by the UBR box of ubiquitin ligasesStructural mechanism of ubiquitin and NEDD8 deamidation catalyzed by bacterial effectors that induce macrophage-specific apoptosis.Emerging Roles of Protein Deamidation in Innate Immune SignalingLiat1, an arginyltransferase-binding protein whose evolution among primates involved changes in the numbers of its 10-residue repeatsLinked production of pyroglutamate-modified proteins via self-cleavage of fusion tags with TEV protease and autonomous N-terminal cyclization with glutaminyl cyclase in vivoAn improved workflow for quantitative N-terminal charge-based fractional diagonal chromatography (ChaFRADIC) to study proteolytic events in Arabidopsis thaliana.Ablation of arginylation in the mouse N-end rule pathway: loss of fat, higher metabolic rate, damaged spermatogenesis, and neurological perturbations.Ubiquitin ligases of the N-end rule pathway: assessment of mutations in UBR1 that cause the Johanson-Blizzard syndromeN-terminal acetylation of cellular proteins creates specific degradation signalsThe N-end rule pathway and regulation by proteolysisUBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells.Thinking outside of the "RGS box": new approaches to therapeutic targeting of regulators of G protein signaling.Crystal structure of human protein N-terminal glutamine amidohydrolase, an initial component of the N-end rule pathway.Expression and biochemical characterization of the human enzyme N-terminal asparagine amidohydrolase.The N-end rule pathway counteracts cell death by destroying proapoptotic protein fragmentsAugmented generation of protein fragments during wakefulness as the molecular cause of sleep: a hypothesis.Degradation of the Separase-cleaved Rec8, a Meiotic Cohesin Subunit, by the N-end Rule Pathway.Molecular characterization of tick salivary gland glutaminyl cyclase.Structural basis for dual specificity of yeast N-terminal amidase in the N-end rule pathway.The auto-generated fragment of the Usp1 deubiquitylase is a physiological substrate of the N-end rule pathway.A single transcription factor is sufficient to induce and maintain secretory cell architectureNew role for an old rule: N-end rule-mediated degradation of ethylene responsive factor proteins governs low oxygen response in plants(F).Formyl-methionine as a degradation signal at the N-termini of bacterial proteins.Physiological functions and clinical implications of the N-end rule pathway.A Viral Deamidase Targets the Helicase Domain of RIG-I to Block RNA-Induced Activation.Degradation of Serotonin N-Acetyltransferase, a Circadian Regulator, by the N-end Rule Pathway.The N-end rule pathway is mediated by a complex of the RING-type Ubr1 and HECT-type Ufd4 ubiquitin ligases.Analyzing N-terminal Arginylation through the Use of Peptide Arrays and Degradation Assays.The N-end rule adaptor protein ClpS from Plasmodium falciparum exhibits broad substrate specificity.The N Termini of TAR DNA-Binding Protein 43 (TDP43) C-Terminal Fragments Influence Degradation, Aggregation Propensity, and Morphology
P2860
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P2860
Glutamine-specific N-terminal amidase, a component of the N-end rule pathway
description
2009 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Juni 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/06/26)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/06/26)
@nl
наукова стаття, опублікована в червні 2009
@uk
مقالة علمية (نشرت في 26-6-2009)
@ar
name
Glutamine-specific N-terminal amidase, a component of the N-end rule pathway
@ast
Glutamine-specific N-terminal amidase, a component of the N-end rule pathway
@en
Glutamine-specific N-terminal amidase, a component of the N-end rule pathway
@nl
type
label
Glutamine-specific N-terminal amidase, a component of the N-end rule pathway
@ast
Glutamine-specific N-terminal amidase, a component of the N-end rule pathway
@en
Glutamine-specific N-terminal amidase, a component of the N-end rule pathway
@nl
prefLabel
Glutamine-specific N-terminal amidase, a component of the N-end rule pathway
@ast
Glutamine-specific N-terminal amidase, a component of the N-end rule pathway
@en
Glutamine-specific N-terminal amidase, a component of the N-end rule pathway
@nl
P2093
P2860
P921
P1433
P1476
Glutamine-specific N-terminal amidase, a component of the N-end rule pathway
@en
P2093
Alexander Varshavsky
Christopher S. Brower
Haiqing Wang
Konstantin I. Piatkov
P2860
P304
P356
10.1016/J.MOLCEL.2009.04.032
P577
2009-06-26T00:00:00Z