A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart
about
AVISPA: a web tool for the prediction and analysis of alternative splicingFormin follows function: a muscle-specific isoform of FHOD3 is regulated by CK2 phosphorylation and promotes myofibril maintenanceHITS-CLIP: panoramic views of protein-RNA regulation in living cellsGlobal regulation of alternative splicing during myogenic differentiationThe pathobiology of splicingThe importance of CELF control: molecular and biological roles of the CUG-BP, Elav-like family of RNA-binding proteinsRNA protein interaction in neuronsThe unstable repeats--three evolving faces of neurological diseaseTranscriptome complexity in cardiac development and diseases--an expanding universe between genome and phenomeTranscriptome analysis reveals strain-specific and conserved stemness genes in Schmidtea mediterraneaStructural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1Identification of variants in MBNL1 in patients with a myotonic dystrophy-like phenotypeAlternative splicing of myomesin 1 gene is aberrantly regulated in myotonic dystrophy type 1The CUGBP2 splicing factor regulates an ensemble of branchpoints from perimeter binding sites with implications for autoregulationMuscle-specific splicing factors ASD-2 and SUP-12 cooperatively switch alternative pre-mRNA processing patterns of the ADF/cofilin gene in Caenorhabditis elegansMBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3The splicing regulators Esrp1 and Esrp2 direct an epithelial splicing program essential for mammalian developmentRNA processing and its regulation: global insights into biological networksRNA and diseaseNKX2-5, a modifier of skeletal muscle pathology due to RNA toxicity.Evaluating the effects of CELF1 deficiency in a mouse model of RNA toxicitySequencing of mRNA identifies re-expression of fetal splice variants in cardiac hypertrophy.Age of onset of RNA toxicity influences phenotypic severity: evidence from an inducible mouse model of myotonic dystrophy (DM1).The alternative heart: impact of alternative splicing in heart disease.PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1.CUGBP1 overexpression in mouse skeletal muscle reproduces features of myotonic dystrophy type 1.RNA splicing regulated by RBFOX1 is essential for cardiac function in zebrafish.Muscleblind-like 1 is required for normal heart valve development in vivo.Comparative analysis of mRNA isoform expression in cardiac hypertrophy and development reveals multiple post-transcriptional regulatory modules.Muscleblind-like 1 knockout mice reveal novel splicing defects in the myotonic dystrophy brainRepression of nuclear CELF activity can rescue CELF-regulated alternative splicing defects in skeletal muscle models of myotonic dystrophyAutoregulation of MBNL1 function by exon 1 exclusion from MBNL1 transcript.The neurofibromatosis type I pre-mRNA is a novel target of CELF protein-mediated splicing regulation.Alternative splicing regulates vesicular trafficking genes in cardiomyocytes during postnatal heart development.Alternative splicing is frequent during early embryonic development in mouse.The epithelial splicing factors ESRP1 and ESRP2 positively and negatively regulate diverse types of alternative splicing events.Heart-specific overexpression of CUGBP1 reproduces functional and molecular abnormalities of myotonic dystrophy type 1.Muscleblind-like 1 is a negative regulator of TGF-beta-dependent epithelial-mesenchymal transition of atrioventricular canal endocardial cells.Targeting DMPK with Antisense Oligonucleotide Improves Muscle Strength in Myotonic Dystrophy Type 1 MiceMicroRNAs coordinate an alternative splicing network during mouse postnatal heart development
P2860
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P248
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P2860
A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart
description
2008 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2008
@ast
im Dezember 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/12/23)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/12/23)
@nl
наукова стаття, опублікована в грудні 2008
@uk
name
A postnatal switch of CELF and ...... licing in the developing heart
@ast
A postnatal switch of CELF and ...... licing in the developing heart
@en
A postnatal switch of CELF and ...... licing in the developing heart
@nl
type
label
A postnatal switch of CELF and ...... licing in the developing heart
@ast
A postnatal switch of CELF and ...... licing in the developing heart
@en
A postnatal switch of CELF and ...... licing in the developing heart
@nl
prefLabel
A postnatal switch of CELF and ...... licing in the developing heart
@ast
A postnatal switch of CELF and ...... licing in the developing heart
@en
A postnatal switch of CELF and ...... licing in the developing heart
@nl
P2093
P2860
P921
P3181
P356
P1476
A postnatal switch of CELF and ...... licing in the developing heart
@en
P2093
Amanda J. Ward
Christopher B. Burge
Jason M. Johnson
John C. Castle
Thomas A. Cooper
P2860
P304
20333–20338
P3181
P356
10.1073/PNAS.0809045105
P407
P577
2008-12-23T00:00:00Z