Muscleblind proteins regulate alternative splicing - Test2 - elhamkhani - TriplyDB

Muscleblind proteins regulate alternative splicing

Muscleblind proteins regulate alternative splicing

http://www.wikidata.org/entity/Q24299521

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Interaction of muscleblind, CUG-BP1 and hnRNP H proteins in DM1-associated aberrant IR splicing MBNL and CELF proteins regulate alternative splicing of the skeletal muscle chloride channel CLCN1 Failure of MBNL1-dependent post-natal splicing transitions in myotonic dystrophy Identification of CELF splicing activation and repression domains in vivo Elevation of RNA-binding protein CUGBP1 is an early event in an inducible heart-specific mouse model of myotonic dystrophy Tissue-dependent isoforms of mammalian Fox-1 homologs are associated with tissue-specific splicing activities.HnRNP H inhibits nuclear export of mRNA containing expanded CUG repeats and a distal branch point sequence.Upregulated genes in sporadic, idiopathic pulmonary arterial hypertension.Mechanisms of RNA-induced toxicity in CAG repeat disorders Transcriptome analysis reveals strain-specific and conserved stemness genes in Schmidtea mediterranea Structural insights into RNA recognition by the alternative-splicing regulator muscleblind-like MBNL1 Solution structure of the RNA binding domain in the human muscleblind-like protein 2 Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1 Utilizing the GAAA Tetraloop/Receptor To Facilitate Crystal Packing and Determination of the Structure of a CUG RNA Helix Alternative splicing of myomesin 1 gene is aberrantly regulated in myotonic dystrophy type 1 Oral administration of erythromycin decreases RNA toxicity in myotonic dystrophy MBNL1 is the primary determinant of focus formation and aberrant insulin receptor splicing in DM1 MBNL1 and PTB cooperate to repress splicing of Tpm1 exon 3 A postnatal switch of CELF and MBNL proteins reprograms alternative splicing in the developing heart The RNA-binding protein SUP-12 controls muscle-specific splicing of the ADF/cofilin pre-mRNA in C. elegans Evaluating the effects of CELF1 deficiency in a mouse model of RNA toxicity Development of an AP-FRET based analysis for characterizing RNA-protein interactions in myotonic dystrophy (DM1)The RNA-binding protein Staufen1 is increased in DM1 skeletal muscle and promotes alternative pre-mRNA splicing Therapeutics development in myotonic dystrophy type 1.New function for the RNA helicase p68/DDX5 as a modifier of MBNL1 activity on expanded CUG repeats Reversible model of RNA toxicity and cardiac conduction defects in myotonic dystrophy.Expanded CTG repeats within the DMPK 3' UTR causes severe skeletal muscle wasting in an inducible mouse model for myotonic dystrophy Woodchuck post-transcriptional element induces nuclear export of myotonic dystrophy 3' untranslated region transcripts.PKC inhibition ameliorates the cardiac phenotype in a mouse model of myotonic dystrophy type 1.Muscleblind-like 1 is required for normal heart valve development in vivo.Cytoplasmic CUG RNA foci are insufficient to elicit key DM1 features.Muscleblind-like 1 knockout mice reveal novel splicing defects in the myotonic dystrophy brain Repression of nuclear CELF activity can rescue CELF-regulated alternative splicing defects in skeletal muscle models of myotonic dystrophy Gene expressions and copy numbers associated with metastatic phenotypes of uterine cervical cancer.Discovery and analysis of evolutionarily conserved intronic splicing regulatory elements.ADAM15 gene structure and differential alternative exon use in human tissues.Drosophila muscleblind is involved in troponin T alternative splicing and apoptosis Genome-wide survey and expression profiling of CCCH-zinc finger family reveals a functional module in macrophage activation.RNA gain-of-function in spinocerebellar ataxia type 8.Muscleblind1, but not Dmpk or Six5, contributes to a complex phenotype of muscular and motivational deficits in mouse models of myotonic dystrophy.

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Muscleblind proteins regulate alternative splicing

http://www.wikidata.org/entity/Q24299521

description

2004 nî lūn-bûn

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2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի օգոստոսին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

@zh-hant

2004年論文

@zh-hk

2004年論文

@zh-mo

2004年論文

@zh-tw

2004年论文

@wuu

name

Muscleblind proteins regulate alternative splicing

@ast

Muscleblind proteins regulate alternative splicing

@en

Muscleblind proteins regulate alternative splicing

@en-gb

Muscleblind proteins regulate alternative splicing

@nl

type

label

Muscleblind proteins regulate alternative splicing

@ast

Muscleblind proteins regulate alternative splicing

@en

Muscleblind proteins regulate alternative splicing

@en-gb

Muscleblind proteins regulate alternative splicing

@nl

prefLabel

Muscleblind proteins regulate alternative splicing

@ast

Muscleblind proteins regulate alternative splicing

@en

Muscleblind proteins regulate alternative splicing

@en-gb

Muscleblind proteins regulate alternative splicing

@nl

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SJ.EMBOJ.7600300

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The EMBO Journal

P1476

Muscleblind proteins regulate alternative splicing

@en

P2093

Gopal Singh

http://www.w3.org/2001/XMLSchema#string

Maurice S Swanson

http://www.w3.org/2001/XMLSchema#string

Michael G Poulos

http://www.w3.org/2001/XMLSchema#string

Nicolas Charlet-B

http://www.w3.org/2001/XMLSchema#string

Thai H Ho

http://www.w3.org/2001/XMLSchema#string

Thomas A Cooper

http://www.w3.org/2001/XMLSchema#string

P2860

Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.

A family of human RNA-binding proteins related to the Drosophila Bruno translational regulator

Recruitment of human muscleblind proteins to (CUG)(n) expansions associated with myotonic dystrophy

The CELF family of RNA binding proteins is implicated in cell-specific and developmentally regulated alternative splicing

Muscle-specific alternative splicing of myotubularin-related 1 gene is impaired in DM1 muscle cells

CELF6, a member of the CELF family of RNA-binding proteins, regulates muscle-specific splicing enhancer-dependent alternative splicing

Functional cloning of BRF1, a regulator of ARE-dependent mRNA turnover.

Visualization of double-stranded RNAs from the myotonic dystrophy protein kinase gene and interactions with CUG-binding protein

CUG repeat binding protein (CUGBP1) interacts with the 5' region of C/EBPbeta mRNA and regulates translation of C/EBPbeta isoforms

In vivo co-localisation of MBNL protein with DMPK expanded-repeat transcripts

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3103-12

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3279045

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10.1038/SJ.EMBOJ.7600300

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15

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23

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2004-08-04T00:00:00Z

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8452874

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15257297

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regulation of RNA splicing

Muscleblind like splicing regulator 1

Muscleblind like splicing regulator 3

Muscleblind like splicing regulator 2

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514918

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