Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway
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Atypical IκB proteins - nuclear modulators of NF-κB signalingRegulation of IkappaBalpha function and NF-kappaB signaling: AEBP1 is a novel proinflammatory mediator in macrophagesSignal-induced ubiquitination of IkappaBalpha by the F-box protein Slimb/beta-TrCPIdentification of the receptor component of the IkappaBalpha-ubiquitin ligaseMetformin in reproductive health, pregnancy and gynaecological cancer: established and emerging indicationsFunctional isoforms of IkappaB kinase alpha (IKKalpha) lacking leucine zipper and helix-loop-helix domains reveal that IKKalpha and IKKbeta have different activation requirementsAnalysis of domains in the IKKalpha and IKKbeta proteins that regulate their kinase activitySuperinduction of CYP1A1 gene expression. Regulation of 2,3,7,8- tetrachlorodibenzo-p-dioxin-induced degradation of Ah receptor by cycloheximideImpairment of NF-kB activation and modulation of gene expression by calpastatinInterleukin-10-mediated Inhibition of free radical generation in macrophagesCIKS, a connection to Ikappa B kinase and stress-activated protein kinasevCLAP, a caspase-recruitment domain-containing protein of equine Herpesvirus-2, persistently activates the Ikappa B kinases through oligomerization of IKKgammaProtein phosphatase 2A interacts with and directly dephosphorylates RelANonstructural 5A protein of hepatitis C virus modulates tumor necrosis factor alpha-stimulated nuclear factor kappa B activationRegulation of SRC-3 (pCIP/ACTR/AIB-1/RAC-3/TRAM-1) Coactivator activity by I kappa B kinase.Inhibition of IkappaB kinase by vaccinia virus virulence factor B14Yeast RSP5 and its human homolog hRPF1 potentiate hormone-dependent activation of transcription by human progesterone and glucocorticoid receptorsDirect involvement of the ubiquitin-conjugating enzyme Ubc9/Hus5 in the degradation of IkappaBalphaI kappa B epsilon, a novel member of the I kappa B family, controls RelA and cRel NF-kappa B activity.Involvement of valosin-containing protein, an ATPase Co-purified with IkappaBalpha and 26 S proteasome, in ubiquitin-proteasome-mediated degradation of IkappaBalpha3-Phosphoinositide-dependent protein kinase-1-mediated IkappaB kinase beta (IkkB) phosphorylation activates NF-kappaB signalingCOMMD1 promotes the ubiquitination of NF-kappaB subunits through a cullin-containing ubiquitin ligaseCCDC22 deficiency in humans blunts activation of proinflammatory NF-κB signalingDNA-dependent protein kinase phosphorylation of IkappaB alpha and IkappaB beta regulates NF-kappaB DNA binding propertiesMolecular determinants of NF-kappaB-inducing kinase actionPhosphorylation of calcipressin 1 increases its ability to inhibit calcineurin and decreases calcipressin half-lifeIkappaB kinase (IKK)-associated protein 1, a common component of the heterogeneous IKK complexIkappaB alpha is a target for the mitogen-activated 90 kDa ribosomal S6 kinase.Modulation of p27(Kip1) levels by the cyclin encoded by Kaposi's sarcoma-associated herpesvirusSEL-10 is an inhibitor of notch signaling that targets notch for ubiquitin-mediated protein degradationRaf kinase inhibitor protein interacts with NF-kappaB-inducing kinase and TAK1 and inhibits NF-kappaB activationIkappaB kinase alpha (IKKalpha) regulation of IKKbeta kinase activityNedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalphaThe Epstein-Barr virus oncoprotein latent membrane protein 1 engages the tumor necrosis factor receptor-associated proteins TRADD and receptor-interacting protein (RIP) but does not induce apoptosis or require RIP for NF-kappaB activationActivation of cyclin E/CDK2 is coupled to site-specific autophosphorylation and ubiquitin-dependent degradation of cyclin ECREB-binding protein/p300 are transcriptional coactivators of p65The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domainCD30-dependent degradation of TRAF2: implications for negative regulation of TRAF signaling and the control of cell survivalThe SCFbeta-TRCP-ubiquitin ligase complex associates specifically with phosphorylated destruction motifs in IkappaBalpha and beta-catenin and stimulates IkappaBalpha ubiquitination in vitroAdenosine and hypoxia-inducible factor signaling in intestinal injury and recovery
P2860
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P2860
Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway
description
1995 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1995
@ast
im Juli 1995 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1995/07/01)
@sk
vědecký článek publikovaný v roce 1995
@cs
wetenschappelijk artikel (gepubliceerd op 1995/07/01)
@nl
наукова стаття, опублікована в липні 1995
@uk
مقالة علمية (نشرت في يوليو 1995)
@ar
name
Signal-induced site-specific p ...... e ubiquitin-proteasome pathway
@ast
Signal-induced site-specific p ...... e ubiquitin-proteasome pathway
@en
Signal-induced site-specific p ...... e ubiquitin-proteasome pathway
@nl
type
label
Signal-induced site-specific p ...... e ubiquitin-proteasome pathway
@ast
Signal-induced site-specific p ...... e ubiquitin-proteasome pathway
@en
Signal-induced site-specific p ...... e ubiquitin-proteasome pathway
@nl
prefLabel
Signal-induced site-specific p ...... e ubiquitin-proteasome pathway
@ast
Signal-induced site-specific p ...... e ubiquitin-proteasome pathway
@en
Signal-induced site-specific p ...... e ubiquitin-proteasome pathway
@nl
P2093
P3181
P356
P1433
P1476
Signal-induced site-specific p ...... e ubiquitin-proteasome pathway
@en
P2093
D. Ballard
D. Scherer
F. Melandri
T. Maniatis
V. J. Palombella
P304
P3181
P356
10.1101/GAD.9.13.1586
P577
1995-07-01T00:00:00Z