Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha
about
Cullin-RING ubiquitin ligases: global regulation and activation cyclesSCF(HOS) ubiquitin ligase mediates the ligand-induced down-regulation of the interferon-alpha receptorHuman HRD1 is an E3 ubiquitin ligase involved in degradation of proteins from the endoplasmic reticulumTRIM40 promotes neddylation of IKKγ and is downregulated in gastrointestinal cancersConservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimerCalcium-dependent regulation of tumour necrosis factor-alpha receptor signalling by copineA unique E1-E2 interaction required for optimal conjugation of the ubiquitin-like protein NEDD8FBXO11 promotes the Neddylation of p53 and inhibits its transcriptional activityStructural insights into NEDD8 activation of cullin-RING ligases: conformational control of conjugationE2-RING expansion of the NEDD8 cascade confers specificity to cullin modificationAn intact NEDD8 pathway is required for Cullin-dependent ubiquitylation in mammalian cells.The CUL1 C-terminal sequence and ROC1 are required for efficient nuclear accumulation, NEDD8 modification, and ubiquitin ligase activity of CUL1Arabidopsis CAND1, an unmodified CUL1-interacting protein, is involved in multiple developmental pathways controlled by ubiquitin/proteasome-mediated protein DegradationControl of cell growth by the SCF and APC/C ubiquitin ligasesPseudosubstrate regulation of the SCF(beta-TrCP) ubiquitin ligase by hnRNP-UDysfunction of amyloid precursor protein signaling in neurons leads to DNA synthesis and apoptosisPlaying Tag with HIF: The VHL StoryFunctional and phylogenetic analysis of the ubiquitylation system in Caenorhabditis elegans: ubiquitin-conjugating enzymes, ubiquitin-activating enzymes, and ubiquitin-like proteinsThe fission yeast COP9/signalosome is involved in cullin modification by ubiquitin-related Ned8pConservation of the COP9/signalosome in budding yeastCullin family proteins and tumorigenesis: genetic association and molecular mechanismsInhibition of NEDD8-conjugation pathway by novel molecules: potential approaches to anticancer therapyBuilding and remodelling Cullin-RING E3 ubiquitin ligasesStructural basis for the function of DCN-1 in protein NeddylationStructural architecture of Galdieria sulphuraria DCN1LRegulation of abiotic stress signal transduction by E3 ubiquitin ligases in Arabidopsis.Actions of adenosine on cullin neddylation: implications for inflammatory responsesCrystal structure of the human COP9 signalosomeA role for Saccharomyces cerevisiae Cul8 ubiquitin ligase in proper anaphase progression.The COP9 signalosome is involved in the regulation of lipid metabolism and of transition metals uptake in Saccharomyces cerevisiae.F-box protein Grr1 interacts with phosphorylated targets via the cationic surface of its leucine-rich repeat.Function and regulation of cullin-RING ubiquitin ligasesSCF(beta-TRCP) and phosphorylation dependent ubiquitinationof I kappa B alpha catalyzed by Ubc3 and Ubc4Targeting of NEDD8 and its conjugates for proteasomal degradation by NUB1The Nedd8-conjugated ROC1-CUL1 core ubiquitin ligase utilizes Nedd8 charged surface residues for efficient polyubiquitin chain assembly catalyzed by Cdc34DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1Phosphorylation of the human ubiquitin-conjugating enzyme, CDC34, by casein kinase 2Human immunodeficiency virus type 1 (HIV-1) Vpr-regulated cell death: insights into mechanismSubstrate-mediated regulation of cullin neddylationMutations in UBA3 confer resistance to the NEDD8-activating enzyme inhibitor MLN4924 in human leukemic cells
P2860
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P2860
Nedd8 modification of cul-1 activates SCF(beta(TrCP))-dependent ubiquitination of IkappaBalpha
description
2000 nî lūn-bûn
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2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Nedd8 modification of cul-1 ac ...... ubiquitination of IkappaBalpha
@ast
Nedd8 modification of cul-1 ac ...... ubiquitination of IkappaBalpha
@en
Nedd8 modification of cul-1 ac ...... ubiquitination of IkappaBalpha
@nl
type
label
Nedd8 modification of cul-1 ac ...... ubiquitination of IkappaBalpha
@ast
Nedd8 modification of cul-1 ac ...... ubiquitination of IkappaBalpha
@en
Nedd8 modification of cul-1 ac ...... ubiquitination of IkappaBalpha
@nl
prefLabel
Nedd8 modification of cul-1 ac ...... ubiquitination of IkappaBalpha
@ast
Nedd8 modification of cul-1 ac ...... ubiquitination of IkappaBalpha
@en
Nedd8 modification of cul-1 ac ...... ubiquitination of IkappaBalpha
@nl
P2093
P2860
P1476
Nedd8 modification of cul-1 ac ...... ubiquitination of IkappaBalpha
@en
P2093
J E Brownell
J W Pierce
L A Parent
M B Coggins
M Hottelet
T B Gladysheva
V J Palombella
P2860
P304
P356
10.1128/MCB.20.7.2326-2333.2000
P407
P577
2000-04-01T00:00:00Z