The protein kinase B/Akt signalling pathway in human malignancy
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Main roads to melanomaExposure to asphalt fumes activates activator protein-1 through the phosphatidylinositol 3-Kinase/Akt signaling pathway in mouse epidermal cellsRaw single-wall carbon nanotubes induce oxidative stress and activate MAPKs, AP-1, NF-kappa B, and Akt in normal and malignant human mesothelial cellsPhosphorylation of CLK2 at serine 34 and threonine 127 by AKT controls cell survival after ionizing radiationA pathway for tumor necrosis factor-alpha-induced Bcl10 nuclear translocation. Bcl10 is up-regulated by NF-kappaB and phosphorylated by Akt1 and then complexes with Bcl3 to enter the nucleus53BP2S, interacting with insulin receptor substrates, modulates insulin signalingEvidence that low doses of Taxol enhance the functional transactivatory properties of p53 on p21 waf promoter in MCF-7 breast cancer cellsAstrocyte elevated gene-1 activates cell survival pathways through PI3K-Akt signalingCARMA1 is required for Akt-mediated NF-kappaB activation in T cells.PIKE-A is amplified in human cancers and prevents apoptosis by up-regulating AktARK5 is a tumor invasion-associated factor downstream of Akt signalingProtein kinases and phosphatases in the control of cell fateTherapeutic potential of mood stabilizers lithium and valproic acid: beyond bipolar disorderTherapeutic Implications of Targeting AKT Signaling in MelanomaRoles of the Raf/MEK/ERK pathway in cell growth, malignant transformation and drug resistanceRegulation of insulin receptor substrate 1 (IRS-1)/AKT kinase-mediated insulin signaling by O-Linked beta-N-acetylglucosamine in 3T3-L1 adipocytesM-T5, the ankyrin repeat, host range protein of myxoma virus, activates Akt and can be functionally replaced by cellular PIKE-AProtein kinase B/Akt binds and phosphorylates PED/PEA-15, stabilizing its antiapoptotic actionAcquisition of anoikis resistance in human osteosarcoma cells does not alter sensitivity to chemotherapeutic agents.Akt2: a role in breast cancer metastasisClassification between normal and tumor tissues based on the pair-wise gene expression ratioRole of APC and DNA mismatch repair genes in the development of colorectal cancers.Increased staining for phospho-Akt, p65/RELA and cIAP-2 in pre-neoplastic human bronchial biopsiesColon cancer and the epidermal growth factor receptor: Current treatment paradigms, the importance of diet, and the role of chemopreventionMetabolic syndrome and renal cell carcinomaPTEN deficiency is associated with reduced sensitivity to mTOR inhibitor in human bladder cancer through the unhampered feedback loop driving PI3K/Akt activationRole of Akt signaling in resistance to DNA-targeted therapyAutophagy, autophagy-associated adaptive immune responses and its role in hematologic malignanciesDisruptive environmental chemicals and cellular mechanisms that confer resistance to cell deathReview on molecular and chemopreventive potential of nimbolide in cancerPIKE (phosphatidylinositol 3-kinase enhancer)-A GTPase stimulates Akt activity and mediates cellular invasionThe Akt pathway regulates survival and homing in Waldenstrom macroglobulinemiaHER2 testing: a review of detection methodologies and their clinical performanceAKT and CDK5/p35 mediate brain-derived neurotrophic factor induction of DARPP-32 in medium size spiny neurons in vitroNanomaterials and autophagy: new insights in cancer treatmentMechanism of Arctigenin-Induced Specific Cytotoxicity against Human Hepatocellular Carcinoma Cell Lines: Hep G2 and SMMC7721Adoptive transfer of heme oxygenase-1 (HO-1)-modified macrophages rescues the nuclear factor erythroid 2-related factor (Nrf2) antiinflammatory phenotype in liver ischemia/reperfusion injuryRole of a novel PH-kinase domain interface in PKB/Akt regulation: structural mechanism for allosteric inhibitionThe serine/threonine kinase Pim-2 is a transcriptionally regulated apoptotic inhibitorAKT1E¹⁷K Is Oncogenic in Mouse Lung and Cooperates with Chemical Carcinogens in Inducing Lung Cancer
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P2860
The protein kinase B/Akt signalling pathway in human malignancy
description
2002 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի մայիսին հրատարակված գիտական հոդված
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artículu científicu espublizáu en 2002
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im Mai 2002 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2002/05/01)
@sk
vědecký článek publikovaný v roce 2002
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wetenschappelijk artikel (gepubliceerd op 2002/05/01)
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наукова стаття, опублікована в травні 2002
@uk
مقالة علمية (نشرت في مايو 2002)
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name
The protein kinase B/Akt signalling pathway in human malignancy
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The protein kinase B/Akt signalling pathway in human malignancy
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The protein kinase B/Akt signalling pathway in human malignancy
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type
label
The protein kinase B/Akt signalling pathway in human malignancy
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The protein kinase B/Akt signalling pathway in human malignancy
@en
The protein kinase B/Akt signalling pathway in human malignancy
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prefLabel
The protein kinase B/Akt signalling pathway in human malignancy
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The protein kinase B/Akt signalling pathway in human malignancy
@en
The protein kinase B/Akt signalling pathway in human malignancy
@nl
P3181
P1433
P1476
The protein kinase B/Akt signalling pathway in human malignancy
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P2093
Karleen M. Nicholson
Neil G. Anderson
P304
P3181
P356
10.1016/S0898-6568(01)00271-6
P577
2002-05-01T00:00:00Z