Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphate
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The LIM protein Ajuba regulates phosphatidylinositol 4,5-bisphosphate levels in migrating cells through an interaction with and activation of PIPKI alphaConversion of PtdIns(4,5)P(2) into PtdIns(5)P by the S.flexneri effector IpgD reorganizes host cell morphologyCloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cellsThe phosphoinositide kinase PIKfyve is vital in early embryonic development: preimplantation lethality of PIKfyve-/- embryos but normality of PIKfyve+/- miceInteraction of the type Ialpha PIPkinase with phospholipase D: a role for the local generation of phosphatidylinositol 4, 5-bisphosphate in the regulation of PLD2 activityPhosphoinositide signaling pathways in nuclei are associated with nuclear speckles containing pre-mRNA processing factorsLoss of Vac14, a regulator of the signaling lipid phosphatidylinositol 3,5-bisphosphate, results in neurodegeneration in mice.Inside-out regulation of ICAM-1 dynamics in TNF-alpha-activated endotheliumIdentification and characterization of a phosphoinositide phosphate kinase homologComplementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinasesPhosphatidylinositol-4-phosphate 5-kinase and GEP100/Brag2 protein mediate antiangiogenic signaling by semaphorin 3E-plexin-D1 through Arf6 proteinAn Arabidopsis inositol phospholipid kinase strongly expressed in procambial cells: synthesis of PtdIns(4,5)P2 and PtdIns(3,4,5)P3 in insect cells by 5-phosphorylation of precursors.Phosphatidylinositol phosphate kinases, a multifaceted family of signaling enzymes.The identification of phosphatidylinositol 3,5-bisphosphate in T-lymphocytes and its regulation by interleukin-2.The emerging role of PtdIns5P: another signalling phosphoinositide takes its place.Overexpression of the amplified Pip4k2beta gene from 17q11-12 in breast cancer cells confers proliferation advantage.Inositol phospholipid metabolism in Arabidopsis. Characterized and putative isoforms of inositol phospholipid kinase and phosphoinositide-specific phospholipase C.Exploring phosphatidylinositol 5-phosphate 4-kinase function.Phosphoinositides and vesicular membrane trafficImaging phosphoinositide dynamics using GFP-tagged protein domains.Distinct roles for the p110alpha and hVPS34 phosphatidylinositol 3'-kinases in vesicular trafficking, regulation of the actin cytoskeleton, and mitogenesis.A novel phosphatidylinositol(3,4,5)P3 pathway in fission yeastPhosphatidylinositol-4-phosphate 5-kinase isoforms exhibit acyl chain selectivity for both substrate and lipid activatorBacterial protein toxins and lipids: role in toxin targeting and activity.Phosphatidylinositol-3,4,5-triphosphate and cellular signaling: implications for obesity and diabetes.A conspicuous connection: structure defines function for the phosphatidylinositol-phosphate kinase family.Mechanism of substrate specificity of phosphatidylinositol phosphate kinases.Role of inositol phospholipid signaling in natural killer cell biology.Phosphatidylinositol 5-phosphate: a nuclear stress lipid and a tuner of membranes and cytoskeleton dynamics.Chemical intervention tools to probe phosphoinositide-dependent signalling.Beta-arrestin scaffolding of phosphatidylinositol 4-phosphate 5-kinase Ialpha promotes agonist-stimulated sequestration of the beta2-adrenergic receptor.hVps34 is a nutrient-regulated lipid kinase required for activation of p70 S6 kinase.Identification of a new polyphosphoinositide in plants, phosphatidylinositol 5-monophosphate (PtdIns5P), and its accumulation upon osmotic stressInhibition of phosphatidic acid synthesis alters the structure of the Golgi apparatus and inhibits secretion in endocrine cells.Stimulation of phosphatidylinositol-4-phosphate 5-kinase by Rho-kinase.Coupled inositide phosphorylation and phospholipase D activation initiates clathrin-coat assembly on lysosomes.Chemical synthesis and molecular recognition of phosphatase-resistant analogues of phosphatidylinositol-3-phosphateAtPIP5K1, an Arabidopsis thaliana phosphatidylinositol phosphate kinase, synthesizes PtdIns(3,4)P(2) and PtdIns(4,5)P(2) in vitro and is inhibited by phosphorylation.Type IIalpha phosphatidylinositol phosphate kinase associates with the plasma membrane via interaction with type I isoforms.Phosphoinositide 3-kinase regulates maturation of lysosomes in rat hepatocytes.
P2860
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P2860
Type I phosphatidylinositol-4-phosphate 5-kinases synthesize the novel lipids phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 5-phosphate
description
1998 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1998
@ast
im Juli 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/07/17)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/07/17)
@nl
наукова стаття, опублікована в липні 1998
@uk
name
Type I phosphatidylinositol-4- ...... osphatidylinositol 5-phosphate
@ast
Type I phosphatidylinositol-4- ...... osphatidylinositol 5-phosphate
@en
Type I phosphatidylinositol-4- ...... osphatidylinositol 5-phosphate
@nl
type
label
Type I phosphatidylinositol-4- ...... osphatidylinositol 5-phosphate
@ast
Type I phosphatidylinositol-4- ...... osphatidylinositol 5-phosphate
@en
Type I phosphatidylinositol-4- ...... osphatidylinositol 5-phosphate
@nl
prefLabel
Type I phosphatidylinositol-4- ...... osphatidylinositol 5-phosphate
@ast
Type I phosphatidylinositol-4- ...... osphatidylinositol 5-phosphate
@en
Type I phosphatidylinositol-4- ...... osphatidylinositol 5-phosphate
@nl
P2093
P2860
P356
P1476
Type I phosphatidylinositol-4- ...... osphatidylinositol 5-phosphate
@en
P2093
C L Carpenter
G D Prestwich
H Ishihara
L C Cantley
Y Shibasaki
P2860
P304
18040-18046
P356
10.1074/JBC.273.29.18040
P407
P50
P577
1998-07-01T00:00:00Z