Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation - Test2 - elhamkhani - TriplyDB

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

http://www.wikidata.org/entity/Q28830194

about

Mechanism and disease association of E2-conjugating enzymes: lessons from UBE2T and UBE2L3 Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation.Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation.Recent advances in quantitative and chemical proteomics for autophagy studies.Activity-Based Probes for HECT E3 Ubiquitin Ligases Activity-based probes for the ubiquitin conjugation-deconjugation machinery: new chemistries, new tools, and new insights.Post translational modification of Parkin.Ubiquitin and Parkinson's disease through the looking glass of genetics.UbMES and UbFluor: Novel probes for ring-between-ring (RBR) E3 ubiquitin ligase PARKIN.2016 EMBO Chemical Biology Conference.Parkinson Disease from Mendelian Forms to Genetic Susceptibility: New Molecular Insights into the Neurodegeneration Process.PINK1 autophosphorylation is required for ubiquitin recognition.Dynamics of PARKIN-Dependent Mitochondrial Ubiquitylation in Induced Neurons and Model Systems Revealed by Digital Snapshot Proteomics.Impact of altered phosphorylation on loss of function of juvenile Parkinsonism-associated genetic variants of the E3 ligase parkin.PICK1 inhibits the E3 ubiquitin ligase activity of Parkin and reduces its neuronal protective effect Mechanism of parkin activation by PINK1

P2860

Q28067393-44FB42DD-14F5-4E78-A158-C4B46242CE92 Q30841625-9B3A1753-2A44-4647-80D2-BB23EF453054 Q37589985-46585E37-9E47-4BCE-A936-3857E201C0F3 Q38640396-BC94EFFB-7B17-4B87-9BBF-D52E9BC3D413 Q38829124-9D6A22C3-9266-42EF-97B8-93EA8CEEE77D Q39135148-6766C383-FFCB-49CA-8963-8BD449058144 Q39145536-9FF4A1CD-CFA4-4F71-8428-F54302E3BA4C Q39241365-62697DE9-6E57-42D2-B26C-93071FAC8411 Q48122567-8A55E8CB-C1A4-454F-9BEC-A74482C60E39 Q48214971-130BEE21-7FC1-4AA1-9743-AA43A5C0F201 Q52559939-0EF18876-92BB-4D3E-BF8F-52721534C91C Q52687770-46020A6D-9396-43C1-9D69-FB08BE9507B0 Q54116010-B07BF965-A377-4B0E-B4DE-2B6C8B5EED6B Q54121802-E3055990-3E06-4EF7-ADB5-49D90095368A Q58478955-1AEFB66F-6C51-4B03-9673-09501824F13E Q59057919-053C0E40-FE9A-4E53-ABD1-910BA94EA454

P2860

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

http://www.wikidata.org/entity/Q28830194

description

2016 nî lūn-bûn

@nan

2016 թուականի Մայիսին հրատարակուած գիտական յօդուած

@hyw

2016 թվականի մայիսին հրատարակված գիտական հոդված

@hy

2016年の論文

@ja

2016年論文

@yue

2016年論文

@zh-hant

2016年論文

@zh-hk

2016年論文

@zh-mo

2016年論文

@zh-tw

2016年论文

@wuu

name

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

@ast

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

@en

type

label

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

@ast

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

@en

prefLabel

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

@ast

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

@en

P1433

Q28830194-262EF9F2-8305-4B99-81EC-09426B5CBFCA

P1476

Q28830194-97DC62BA-1CF8-42C3-931C-DC2507863450

P2093

Q28830194-13F4DAC5-53DC-4341-B3C2-651EF08B6333

Q28830194-19DAF165-194F-4692-8FF1-B284077FA944

Q28830194-7B948844-6081-41D9-B029-507CBEAC7526

Q28830194-8C0F520A-8DED-4C93-B6C1-2871E20124AD

Q28830194-A3E05052-0CC1-4D94-BE2D-2425894D14B7

P2860

Q28830194-10908CC6-B7C6-4144-BC93-D6A1410A7938

Q28830194-16A6A0E7-6BB2-4725-8CCA-F5694F58AA6F

Q28830194-18667730-28B6-4AE2-B371-01A04CA56845

Q28830194-2378F285-7AD5-4E4E-B829-B24631E48B83

Q28830194-24B58799-3781-48FE-B545-F58F15C5FC57

Q28830194-2A83B7ED-3977-4968-8DBD-81B3DC937BD1

Q28830194-2D02CCAA-ACB2-42D4-A421-0BD0EAFE2FA7

Q28830194-2E9B9316-CB1B-418A-BCDF-FF0F6DB13B32

Q28830194-31EC25ED-1491-4F22-9EB0-B17A196593A5

Q28830194-347F66FF-BCE6-4A65-938B-BBB38A043D54

P2888

Q28830194-5FB344F6-0D53-4CFD-9507-2599E8384443

P304

Q28830194-A9324086-0135-4682-878B-A07BB7B1745F

P31

Q28830194-83923C85-513F-46A4-BF74-2B68E4C147EB

P3181

Q28830194-5EB3B164-3319-4A3C-827A-C5756AB0D9BC

P356

Q28830194-149E0BDD-461B-4972-B15B-0FA4D685B8CC

P407

Q28830194-F6114E9D-5691-442D-88FB-D34C3A5238ED

P433

Q28830194-46A8EDB1-FC1B-402E-BB6F-D12DC128FC6F

P478

Q28830194-97083C62-B194-4896-B8D7-E67FE643288B

P50

Q28830194-0E47D768-B503-4BCB-837B-B93620ABD0C8

Q28830194-195700BD-9890-4D7B-8D9D-37E1770A44D6

Q28830194-2F26A8C8-6AD9-446D-9B97-A822DEF37A97

Q28830194-4A6C048B-D99A-418D-9B31-1F454E04266A

Q28830194-6077A178-C892-483D-A545-4DA8E7EA2471

Q28830194-A51AD392-CB58-47B0-80EA-9135164B676B

P577

Q28830194-99AFC0C2-7BA2-4247-95C5-82884AAC9669

P6179

Q28830194-418ADBF7-27A7-4576-9391-1D01EC4D4219

P698

Q28830194-F533DFC9-8A5B-425F-B2A3-79021DD43669

P921

Q28830194-F47F5CAF-D03B-4BE2-BBE0-56E861B2FE4B

P932

Q28830194-AA54D455-7891-4406-880C-47CEF655DA86

P3181

P356

P1433

Nature Chemical Biology

P1476

Probes of ubiquitin E3 ligases enable systematic dissection of parkin activation

@en

P2093

Cong Han

http://www.w3.org/2001/XMLSchema#string

Kristin Balk

http://www.w3.org/2001/XMLSchema#string

Kuan-Chuan Pao

http://www.w3.org/2001/XMLSchema#string

Miratul M K Muqit

http://www.w3.org/2001/XMLSchema#string

Paul Murphy

http://www.w3.org/2001/XMLSchema#string

P2860

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65

LUBAC synthesizes linear ubiquitin chains via a thioester intermediate

Ubiquitin is phosphorylated by PINK1 to activate parkin

Active site remodelling accompanies thioester bond formation in the SUMO E1

UBCH7 reactivity profile reveals parkin and HHARI to be RING/HECT hybrids

Autoregulation of Parkin activity through its ubiquitin-like domain

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

PINK1 and Parkin – mitochondrial interplay between phosphorylation and ubiquitylation in Parkinson's disease

Insights into Ubiquitin Transfer Cascades from a Structure of a UbcH5B∼Ubiquitin-HECTNEDD4L Complex

P2888

P304

324-331

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

3215128

http://www.w3.org/2001/XMLSchema#string

P356

10.1038/NCHEMBIO.2045

http://www.w3.org/2001/XMLSchema#string

P407

P433

5

http://www.w3.org/2001/XMLSchema#string

P478

12

http://www.w3.org/2001/XMLSchema#string

P50

Jean-Christophe Corvol

P577

2016-05-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P6179

1036481694

http://www.w3.org/2001/XMLSchema#string

P698

26928937

http://www.w3.org/2001/XMLSchema#string

P921

P932

4909137

http://www.w3.org/2001/XMLSchema#string