Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
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The foxa2 gene controls the birth and spontaneous degeneration of dopamine neurons in old ageUbiquitin-proteasome system involvement in Huntington's diseaseProgression of Parkinson's disease pathology is reproduced by intragastric administration of rotenone in miceA two-stage meta-analysis identifies several new loci for Parkinson's diseaseWeb-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's diseaseRanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolismEarly onset torsion dystonia (Oppenheim's dystonia)Proteome analysis of human substantia nigra in Parkinson's diseaseSulforaphane as a potential protective phytochemical against neurodegenerative diseasesParkinson's disease-associated kinase PINK1 regulates Miro protein level and axonal transport of mitochondriaThe DNA sequence and analysis of human chromosome 6Cloning and characterization of a novel human phosphodiesterase that hydrolyzes both cAMP and cGMP (PDE10A)TRIADs: a new class of proteins with a novel cysteine-rich signatureGenetic perspective on the role of the autophagy-lysosome pathway in Parkinson diseaseGenetic etiology of Parkinson disease associated with mutations in the SNCA, PARK2, PINK1, PARK7, and LRRK2 genes: a mutation updateThe genetic epidemiology of neurodegenerative disease.Modifying welding process parameters can reduce the neurotoxic potential of manganese-containing welding fumesParkin functions as an E2-dependent ubiquitin- protein ligase and promotes the degradation of the synaptic vesicle-associated protein, CDCrel-1Features of the parkin/ariadne-like ubiquitin ligase, HHARI, that regulate its interaction with the ubiquitin-conjugating enzyme, Ubch7Parkin is activated by PINK1-dependent phosphorylation of ubiquitin at Ser65Endoplasmic reticulum stress and Parkinson's disease: the role of HRD1 in averting apoptosis in neurodegenerative diseaseUbiquitin is phosphorylated by PINK1 to activate parkinParkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicityPINK1 and Parkin target Miro for phosphorylation and degradation to arrest mitochondrial motilityPARK13 regulates PINK1 and subcellular relocation patterns under oxidative stress in neuronsA product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell deathParkin ubiquitinates and promotes the degradation of RanBP2Leucine-rich repeat kinase 2 (LRRK2) interacts with parkin, and mutant LRRK2 induces neuronal degeneration.The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagyMUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkinDJ-1 interacts with RACK1 and protects neurons from oxidative-stress-induced apoptosisMutations in PTEN-induced putative kinase 1 associated with recessive parkinsonism have differential effects on protein stabilityMitochondrial Parkin recruitment is impaired in neurons derived from mutant PINK1 induced pluripotent stem cellsStaring, a novel E3 ubiquitin-protein ligase that targets syntaxin 1 for degradationMitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cellsParkin controls dopamine utilization in human midbrain dopaminergic neurons derived from induced pluripotent stem cellsPhosphatase and tensin homolog (PTEN)-induced putative kinase 1 (PINK1)-dependent ubiquitination of endogenous Parkin attenuates mitophagy: study in human primary fibroblasts and induced pluripotent stem cell-derived neuronsParkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer modelInteraction of DJ-1 with Daxx inhibits apoptosis signal-regulating kinase 1 activity and cell deathDJ-1 has a role in antioxidative stress to prevent cell death
P2860
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P2860
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
description
1998 nî lūn-bûn
@nan
1998 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@ast
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@en
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@en-gb
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@nl
type
label
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@ast
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@en
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@en-gb
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@nl
prefLabel
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@ast
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@en
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@en-gb
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@nl
P2093
P3181
P356
P1433
P1476
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
@en
P2093
H Matsumine
S Minoshima
Y Yamamura
P2888
P356
10.1038/33416
P407
P577
1998-04-09T00:00:00Z
P6179
1007440052