A simple physical model for binding energy hot spots in protein-protein complexes
about
Sequence co-evolution gives 3D contacts and structures of protein complexesDisentangling direct from indirect co-evolution of residues in protein alignmentsEpistructural Tension Promotes Protein AssociationsTrp-26 imparts functional versatility to human alpha-defensin HNP1Systematic analysis of helical protein interfaces reveals targets for synthetic inhibitorsIn silico screening of mutational effects on enzyme-proteic inhibitor affinity: a docking-based approachProtein-DNA binding specificity predictions with structural modelsImprovement in protein functional site prediction by distinguishing structural and functional constraints on protein family evolution using computational design.Oligomeric protein structure networks: insights into protein-protein interactions.An Integrated Framework Advancing Membrane Protein Modeling and DesignIn silico prediction of mutant HIV-1 proteases cleaving a target sequenceStructure-based Protocol for Identifying Mutations that Enhance Protein–Protein Binding AffinitiesA New Twist in TCR Diversity Revealed by a Forbidden αβ TCRThe crystal structure and dimerization interface of GADD45γCrystal Structure of the Engineered Neutralizing Antibody M18 Complexed to Domain 4 of the Anthrax Protective AntigenSystematic Mutational Analysis of Peptide Inhibition of the p53–MDM2/MDMX InteractionsLimitations of Peptide Retro-inverso Isomerization in Molecular MimicryStructural Determinants of Affinity Enhancement between GoLoco Motifs and G-Protein Subunit MutantsMolecular Basis of a Million-Fold Affinity Maturation Process in a Protein–Protein InteractionControl of protein signaling using a computationally designed GTPase/GEF orthogonal pairStructurally Conserved Nop56/58 N-terminal Domain Facilitates Archaeal Box C/D Ribonucleoprotein-guided Methyltransferase ActivityComputational Design of the Affinity and Specificity of a Therapeutic T Cell ReceptorCrystal structure of Streptococcus pyogenes EndoS, an immunomodulatory endoglycosidase specific for human IgG antibodiesStructural basis of the heterodimerization of the MST and RASSF SARAH domains in the Hippo signalling pathwayImproving binding affinity and stability of peptide ligands by substituting glycines with D-amino acidsPlasmodium falciparum Hsp70-x: a heat shock protein at the host-parasite interfaceProTherm, version 4.0: thermodynamic database for proteins and mutantsProtein-protein interaction hotspots carved into sequencesThe overlap of small molecule and protein binding sites within families of protein structuresModeling the ternary complex TCR-Vbeta/CollagenII(261-273)/HLA-DR4 associated with rheumatoid arthritisModeling of arylamide helix mimetics in the p53 peptide binding site of hDM2 suggests parallel and anti-parallel conformations are both stable.Quantitative predictions of binding free energy changes in drug-resistant influenza neuraminidaseLocal network patterns in protein-protein interfacesCharacterizing changes in the rate of protein-protein dissociation upon interface mutation using hotspot energy and organizationCombining structural modeling with ensemble machine learning to accurately predict protein fold stability and binding affinity effects upon mutationSelectivity by small-molecule inhibitors of protein interactions can be driven by protein surface fluctuationsDnaK as Antibiotic Target: Hot Spot Residues Analysis for Differential Inhibition of the Bacterial Protein in Comparison with the Human HSP70Deciphering Dimerization Modes of PAS Domains: Computational and Experimental Analyses of the AhR:ARNT Complex Reveal New Insights Into the Mechanisms of AhR TransformationInterolog interfaces in protein-protein dockingDetermination of ubiquitin fitness landscapes under different chemical stresses in a classroom setting
P2860
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P2860
A simple physical model for binding energy hot spots in protein-protein complexes
description
2002 nî lūn-bûn
@nan
2002 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
A simple physical model for binding energy hot spots in protein-protein complexes
@ast
A simple physical model for binding energy hot spots in protein-protein complexes
@en
type
label
A simple physical model for binding energy hot spots in protein-protein complexes
@ast
A simple physical model for binding energy hot spots in protein-protein complexes
@en
prefLabel
A simple physical model for binding energy hot spots in protein-protein complexes
@ast
A simple physical model for binding energy hot spots in protein-protein complexes
@en
P2860
P3181
P356
P1476
A simple physical model for binding energy hot spots in protein-protein complexes
@en
P2860
P304
P3181
P356
10.1073/PNAS.202485799
P407
P577
2002-10-29T00:00:00Z