Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
about
Epigenetic effects of stress and corticosteroids in the brainA role for methyl-CpG binding domain protein 2 in the modulation of the estrogen response of pS2/TFF1 geneEpigenetic overlap in autism-spectrum neurodevelopmental disorders: MECP2 deficiency causes reduced expression of UBE3A and GABRB3.Interaction between chromatin proteins MECP2 and ATRX is disrupted by mutations that cause inherited mental retardationA family of human zinc finger proteins that bind methylated DNA and repress transcriptionFunctional consequences of mutations in CDKL5, an X-linked gene involved in infantile spasms and mental retardationCDKL5 belongs to the same molecular pathway of MeCP2 and it is responsible for the early-onset seizure variant of Rett syndromeRegulation of MBD1-mediated transcriptional repression by SUMO and PIAS proteinsMethyl-CpG-binding protein 2 is phosphorylated by homeodomain-interacting protein kinase 2 and contributes to apoptosisReelin and glutamic acid decarboxylase67 promoter remodeling in an epigenetic methionine-induced mouse model of schizophreniaSpecific binding of the methyl binding domain protein 2 at the BRCA1-NBR2 locus.Mutations in the X-linked cyclin-dependent kinase-like 5 (CDKL5/STK9) gene are associated with severe neurodevelopmental retardationT-bet antagonizes mSin3a recruitment and transactivates a fully methylated IFN-gamma promoter via a conserved T-box half-siteExpression of MeCP2 in postmitotic neurons rescues Rett syndrome in miceMbd1 is recruited to both methylated and nonmethylated CpGs via distinct DNA binding domainsSocial influences on neurobiology and behavior: epigenetic effects during development.Epigenetic regulation of neurogenesis in the adult mammalian brainEmerging pharmacotherapies for neurodevelopmental disordersMutations in DNMT1 cause hereditary sensory neuropathy with dementia and hearing lossHistone deactylase 1 expression is increased in the prefrontal cortex of schizophrenia subjects: analysis of the National Brain Databank microarray collectionBrain-derived neurotrophic factorBrain foods: the effects of nutrients on brain functionBrain-derived neurotrophic factor: role in depression and suicideMeCP2, a key contributor to neurological disease, activates and represses transcriptionThe common BDNF polymorphism may be a modifier of disease severity in Rett syndromeSignaling mechanisms linking neuronal activity to gene expression and plasticity of the nervous systemCDKL5 expression is modulated during neuronal development and its subcellular distribution is tightly regulated by the C-terminal tailPartial reversal of Rett Syndrome-like symptoms in MeCP2 mutant miceAmpakines cause sustained increases in brain-derived neurotrophic factor signaling at excitatory synapses without changes in AMPA receptor subunit expressionHypomethylation of MB-COMT promoter is a major risk factor for schizophrenia and bipolar disorderReciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autismIntegrated epigenomic analyses of neuronal MeCP2 reveal a role for long-range interaction with active genesThe odyssey of MeCP2 and parental imprintingRett syndrome: clinical review and genetic updateNeurotrophin-regulated signalling pathwaysAutistic-like phenotypes in Cadps2-knockout mice and aberrant CADPS2 splicing in autistic patients.Inhibitors of differentiation (ID1, ID2, ID3 and ID4) genes are neuronal targets of MeCP2 that are elevated in Rett syndromeBoth 5' and 3' flanks regulate Zebrafish brain-derived neurotrophic factor gene expressionExpression, purification and characterization of methyl DNA binding protein from Bombyx mori.Structure-specific binding of MeCP2 to four-way junction DNA through its methyl CpG-binding domain
P2860
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P2860
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
description
2003 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2003
@ast
im Oktober 2003 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
wetenschappelijk artikel (gepubliceerd op 2003/10/31)
@nl
наукова стаття, опублікована в жовтні 2003
@uk
مقالة علمية (نشرت في 31-10-2003)
@ar
name
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
@ast
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
@en
type
label
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
@ast
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
@en
prefLabel
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
@ast
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
@en
P2093
P3181
P356
P1433
P1476
Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2
@en
P2093
Anne E. West
Eric C. Griffith
Michael E. Greenberg
Qiang Chang
Wen G. Chen
Yingxi Lin
P304
P3181
P356
10.1126/SCIENCE.1086446
P407
P577
2003-10-31T00:00:00Z