Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase
about
Definitive identification of mammalian 5-hydroxymethyluracil DNA N-glycosylase activity as SMUG1Lesion processing by a repair enzyme is severely curtailed by residues needed to prevent aberrant activity on undamaged DNAModification of the human thymine-DNA glycosylase by ubiquitin-like proteins facilitates enzymatic turnoverReconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 proteinMethylated DNA-binding domain 1 and methylpurine-DNA glycosylase link transcriptional repression and DNA repair in chromatinDNA glycosylases: in DNA repair and beyondMismatch Repair in Methylated DNA: STRUCTURE AND ACTIVITY OF THE MISMATCH-SPECIFIC THYMINE GLYCOSYLASE DOMAIN OF METHYL-CpG-BINDING PROTEIN MBD4Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residuesInvestigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domainBiphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylaseCovalent modification of p73alpha by SUMO-1. Two-hybrid screening with p73 identifies novel SUMO-1-interacting proteins and a SUMO-1 interaction motifThe DNA glycosylase T:G mismatch-specific thymine DNA glycosylase represses thyroid transcription factor-1-activated transcriptionThe main role of human thymine-DNA glycosylase is removal of thymine produced by deamination of 5-methylcytosine and not removal of ethenocytosineRole of base excision repair in maintaining the genetic and epigenetic integrity of CpG sitesMBD4 and TDG: multifaceted DNA glycosylases with ever expanding biological rolesNoncovalent SUMO-1 binding activity of thymine DNA glycosylase (TDG) is required for its SUMO-1 modification and colocalization with the promyelocytic leukemia proteinMethylation mattersHighly efficient base excision repair (BER) in human and rat male germ cellsAnalysis of uracil-DNA glycosylases from the murine Ung gene reveals differential expression in tissues and in embryonic development and a subcellular sorting pattern that differs from the human homologuesOpposing regulatory roles of phosphorylation and acetylation in DNA mispair processing by thymine DNA glycosylaseA 55-kDa protein isolated from human cells shows DNA glycosylase activity toward 3,N4-ethenocytosine and the G/T mismatchMutational analysis of arginine 276 in the leucine-loop of human uracil-DNA glycosylase.Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNALists of HumanMethylation450 BeadChip probes with nucleotide-variant information obtained from the Phase 3 data of the 1000 Genomes ProjectRecent progress in the biology, chemistry and structural biology of DNA glycosylases.5-methylcytosine-DNA glycosylase activity is present in a cloned G/T mismatch DNA glycosylase associated with the chicken embryo DNA demethylation complexHuman DNA repair systems: an overview.Enzymatic and chemical cleavage methods.SUMO-1 regulates the conformational dynamics of thymine-DNA Glycosylase regulatory domain and competes with its DNA binding activity.Characterization of a thermostable DNA glycosylase specific for U/G and T/G mismatches from the hyperthermophilic archaeon Pyrobaculum aerophilum.Reduced rates of gene loss, gene silencing, and gene mutation in Dnmt1-deficient embryonic stem cells.An approach for global scanning of single nucleotide variationsE2-mediated small ubiquitin-like modifier (SUMO) modification of thymine DNA glycosylase is efficient but not selective for the enzyme-product complex.Escherichia coli DNA glycosylase Mug: a growth-regulated enzyme required for mutation avoidance in stationary-phase cells.Role of MED1 (MBD4) Gene in DNA repair and human cancer.Base excision repair in a network of defence and tolerance.Oxidative DNA damage induced by copper and hydrogen peroxide promotes CG-->TT tandem mutations at methylated CpG dinucleotides in nucleotide excision repair-deficient cells.Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase.MED1: a central molecule for maintenance of genome integrity and response to DNA damageFunctional interactions and signaling properties of mammalian DNA mismatch repair proteins.
P2860
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P2860
Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase
description
1996 nî lūn-bûn
@nan
1996 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
name
Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase
@ast
Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase
@en
type
label
Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase
@ast
Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase
@en
prefLabel
Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase
@ast
Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase
@en
P2860
P3181
P356
P1476
Cloning and Expression of Human G/T Mismatch-specific Thymine-DNA Glycosylase
@en
P2093
P. Gallinari
P2860
P304
12767-12774
P3181
P356
10.1074/JBC.271.22.12767
P407
P577
1996-05-31T00:00:00Z