Efficient removal of uracil from G.U mispairs by the mismatch-specific thymine DNA glycosylase from HeLa cells
about
Elevated levels of mutation in multiple tissues of mice deficient in the DNA mismatch repair gene Pms2Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylaseInvestigation of the substrate spectrum of the human mismatch-specific DNA N-glycosylase MED1 (MBD4): fundamental role of the catalytic domainBiphasic kinetics of the human DNA repair protein MED1 (MBD4), a mismatch-specific DNA N-glycosylaseCloning and Expression of Human G/T Mismatch-specific Thymine-DNA GlycosylaseExcision of 5-halogenated uracils by human thymine DNA glycosylase. Robust activity for DNA contexts other than CpG.Uracil DNA glycosylase (UDG) activities in Bradyrhizobium diazoefficiens: characterization of a new class of UDG with broad substrate specificity.SUMO-1 regulates the conformational dynamics of thymine-DNA Glycosylase regulatory domain and competes with its DNA binding activity.A phylogenomic study of DNA repair genes, proteins, and processes.Base excision repair of DNA in mammalian cells.Escherichia coli DNA glycosylase Mug: a growth-regulated enzyme required for mutation avoidance in stationary-phase cells.Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice.Evidence for independent mismatch repair processing on opposite sides of a double-strand break in Saccharomyces cerevisiae.Efficient repair of all types of single-base mismatches in recombination intermediates in Chinese hamster ovary cells. Competition between long-patch and G-T glycosylase-mediated repair of G-T mismatches.Processing of deoxyuridine mismatches and abasic sites by human immunodeficiency virus type-1 integrase.Ligation of multiple DNA fragments through uracil-DNA glycosylase generated ligation sitesUracil in duplex DNA is a substrate for the nucleotide incision repair pathway in human cells.Phylogenomic analysis of the uracil-DNA glycosylase superfamilyEnzymology of the repair of free radicals-induced DNA damage.Crossovers are associated with mutation and biased gene conversion at recombination hotspotsA mutant of uracil DNA glycosylase that distinguishes between cytosine and 5-methylcytosineAn unexpectedly high excision capacity for mispaired 5-hydroxymethyluracil in human cell extracts.Oxidized, deaminated cytosines are a source of C --> T transitions in vivoProtein p56 from the Bacillus subtilis phage phi29 inhibits DNA-binding ability of uracil-DNA glycosylase.A density functional theory study on the kinetics and thermodynamics of N-glycosidic bond cleavage in 5-substituted 2'-deoxycytidinesMultifaceted roles for thymine DNA glycosylase in embryonic development and human carcinogenesisBase excision repair in physiology and pathology of the central nervous system7,8-Dihydro-8-oxoadenine, a highly mutagenic adduct, is repaired by Escherichia coli and human mismatch-specific uracil/thymine-DNA glycosylases.Investigation of the mechanisms of DNA binding of the human G/T glycosylase using designed inhibitors.Non-canonical uracil processing in DNA gives rise to double-strand breaks and deletions: relevance to class switch recombinationMonitoring eukaryotic and bacterial UDG repair activity with DNA-multifluorophore sensorsAP endonuclease 1 prevents the extension of a T/G mismatch by DNA polymerase β to prevent mutations in CpGs during base excision repairInterference of mismatch and base excision repair during the processing of adjacent U/G mispairs may play a key role in somatic hypermutationEpigenetic reprogramming: is deamination key to active DNA demethylation?Base-excision repair activity of uracil-DNA glycosylase monitored using the latch zone of α-hemolysin.DNA base repair--recognition and initiation of catalysis.DNA demethylation by TDG.Human thymine DNA glycosylase binds to apurinic sites in DNA but is displaced by human apurinic endonuclease 1.Specific binding of a designed pyrrolidine abasic site analog to multiple DNA glycosylases.Thymine DNA glycosylase modulates DNA damage response and gene expression by base excision repair-dependent and independent mechanisms.
P2860
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P2860
Efficient removal of uracil from G.U mispairs by the mismatch-specific thymine DNA glycosylase from HeLa cells
description
1994 nî lūn-bûn
@nan
1994 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի մարտին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年論文
@yue
1994年論文
@zh-hant
1994年論文
@zh-hk
1994年論文
@zh-mo
1994年論文
@zh-tw
1994年论文
@wuu
name
Efficient removal of uracil fr ...... NA glycosylase from HeLa cells
@ast
Efficient removal of uracil fr ...... NA glycosylase from HeLa cells
@en
Efficient removal of uracil fr ...... NA glycosylase from HeLa cells
@nl
type
label
Efficient removal of uracil fr ...... NA glycosylase from HeLa cells
@ast
Efficient removal of uracil fr ...... NA glycosylase from HeLa cells
@en
Efficient removal of uracil fr ...... NA glycosylase from HeLa cells
@nl
prefLabel
Efficient removal of uracil fr ...... NA glycosylase from HeLa cells
@ast
Efficient removal of uracil fr ...... NA glycosylase from HeLa cells
@en
Efficient removal of uracil fr ...... NA glycosylase from HeLa cells
@nl
P2860
P356
P1476
Efficient removal of uracil fr ...... NA glycosylase from HeLa cells
@en
P2093
P Neddermann
P2860
P304
P356
10.1073/PNAS.91.5.1642
P407
P577
1994-03-01T00:00:00Z