Definitive identification of mammalian 5-hydroxymethyluracil DNA N-glycosylase activity as SMUG1
about
Tissue distribution of 5-hydroxymethylcytosine and search for active demethylation intermediatesActions of aprataxin in multiple DNA repair pathwaysHydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brainThymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sitesSMUG1 is able to excise uracil from immunoglobulin genes: insight into mutation versus repairMutational analysis of the damage-recognition and catalytic mechanism of human SMUG1 DNA glycosylaseTet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNAUracil-DNA glycosylases SMUG1 and UNG2 coordinate the initial steps of base excision repair by distinct mechanismsThe current state of eukaryotic DNA base damage and repairDNA glycosylases: in DNA repair and beyondActivation-induced cytidine deaminase deaminates 5-methylcytosine in DNA and is expressed in pluripotent tissues: implications for epigenetic reprogrammingCockayne syndrome B protein stimulates apurinic endonuclease 1 activity and protects against agents that introduce base excision repair intermediatesC --> T mutagenesis and gamma-radiation sensitivity due to deficiency in the Smug1 and Ung DNA glycosylasesThe effect of Pot1 binding on the repair of thymine analogs in a telomeric DNA sequenceActive DNA demethylation: many roads lead to Rome.Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice.Intrinsic apurinic/apyrimidinic (AP) endonuclease activity enables Bacillus subtilis DNA polymerase X to recognize, incise, and further repair abasic sites.Clustered DNA damage induced by gamma radiation in human fibroblasts (HF19), hamster (V79-4) cells and plasmid DNA is revealed as Fpg and Nth sensitive sitesEndonuclease IV Is the major apurinic/apyrimidinic endonuclease in Mycobacterium tuberculosis and is important for protection against oxidative damageBase excision repair and lesion-dependent subpathways for repair of oxidative DNA damage.Phylogenomic analysis of the uracil-DNA glycosylase superfamilySynergistic enhancement of 5-fluorouracil cytotoxicity by deoxyuridine analogs in cancer cells.UNG-initiated base excision repair is the major repair route for 5-fluorouracil in DNA, but 5-fluorouracil cytotoxicity depends mainly on RNA incorporation.Genetic variability in DNA repair proteins in age-related macular degeneration.Genomically Incorporated 5-Fluorouracil that Escapes UNG-Initiated Base Excision Repair Blocks DNA Replication and Activates Homologous RecombinationMeasurement of the incorporation and repair of exogenous 5-hydroxymethyl-2'-deoxyuridine in human cells in culture using gas chromatography-negative chemical ionization-mass spectrometry.Mechanisms of base selection by human single-stranded selective monofunctional uracil-DNA glycosylaseEpigenetic changes in the progression of Alzheimer's disease.DNA base repair--recognition and initiation of catalysis.Vpr expression abolishes the capacity of HIV-1 infected cells to repair uracilated DNA.Repair of U/G and U/A in DNA by UNG2-associated repair complexes takes place predominantly by short-patch repair both in proliferating and growth-arrested cells.Biosynthesis and molecular genetics of polyketides in marine dinoflagellates.Dual roles of DNA repair enzymes in RNA biology/post-transcriptional control.Role of Base Excision "Repair" Enzymes in Erasing Epigenetic Marks from DNADNA demethylation pathways: Additional players and regulators.Alternative roles for oxidized mCs and TETs.Formation and repair of oxidatively generated damage in cellular DNA.Epigenetic dysregulation of hematopoietic stem cells and preleukemic state.Expression of the human DNA glycosylase hSMUG1 in Trypanosoma brucei causes DNA damage and interferes with J biosynthesis.Identification of high excision capacity for 5-hydroxymethyluracil mispaired with guanine in DNA of Escherichia coli MutM, Nei and Nth DNA glycosylases.
P2860
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P2860
Definitive identification of mammalian 5-hydroxymethyluracil DNA N-glycosylase activity as SMUG1
description
2001 nî lūn-bûn
@nan
2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Definitive identification of m ...... -glycosylase activity as SMUG1
@ast
Definitive identification of m ...... -glycosylase activity as SMUG1
@en
Definitive identification of m ...... -glycosylase activity as SMUG1
@en-gb
Definitive identification of m ...... -glycosylase activity as SMUG1
@nl
type
label
Definitive identification of m ...... -glycosylase activity as SMUG1
@ast
Definitive identification of m ...... -glycosylase activity as SMUG1
@en
Definitive identification of m ...... -glycosylase activity as SMUG1
@en-gb
Definitive identification of m ...... -glycosylase activity as SMUG1
@nl
prefLabel
Definitive identification of m ...... -glycosylase activity as SMUG1
@ast
Definitive identification of m ...... -glycosylase activity as SMUG1
@en
Definitive identification of m ...... -glycosylase activity as SMUG1
@en-gb
Definitive identification of m ...... -glycosylase activity as SMUG1
@nl
P2093
P2860
P356
P1476
Definitive identification of m ...... -glycosylase activity as SMUG1
@en
P2093
Boorstein RJ
Cummings A Jr
Marenstein DR
Neubert TA
P2860
P304
41991-41997
P356
10.1074/JBC.M106953200
P407
P577
2001-08-28T00:00:00Z