CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes
about
Regulation of HOXA2 gene expression by the ATP-dependent chromatin remodeling enzyme CHD8Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathwayDisruptive CHD8 mutations define a subtype of autism early in developmentCHD8 interacts with CHD7, a protein which is mutated in CHARGE syndromeMolecular and phenotypic aspects of CHD7 mutation in CHARGE syndromeThe chromatin remodeling factor CHD8 interacts with elongating RNA polymerase II and controls expression of the cyclin E2 geneSynaptic Wnt/GSK3β Signaling Hub in AutismA double take on bivalent promotersHistone methylation makes its mark on longevityOn WD40 proteins: propelling our knowledge of transcriptional control?Characterization of a Novel WDR5-binding Site That Recruits RbBP5 through a Conserved Motif to Enhance Methylation of Histone H3 Lysine 4 by Mixed Lineage Leukemia Protein-1Structural basis for activity regulation of MLL family methyltransferasesWnt signaling networks in autism spectrum disorder and intellectual disabilityThe BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotypeMultiplex targeted sequencing identifies recurrently mutated genes in autism spectrum disordersCHD5 is required for spermiogenesis and chromatin condensationX-linked mental retardation gene CUL4B targets ubiquitylation of H3K4 methyltransferase component WDR5 and regulates neuronal gene expressionA role for WDR5 in TRA-1/Gli mediated transcriptional control of the sperm/oocyte switch in C. elegansSporadic autism exomes reveal a highly interconnected protein network of de novo mutationsWD repeat-containing protein 5, a ubiquitously expressed histone methyltransferase adaptor protein, regulates smooth muscle cell-selective gene activation through interaction with pituitary homeobox 2.Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signalingInteraction between Hhex and SOX13 modulates Wnt/TCF activityFrom neural development to cognition: unexpected roles for chromatin.Deletion of the Chd6 exon 12 affects motor coordination.A de novo convergence of autism genetics and molecular neuroscience.Regulation of androgen-responsive transcription by the chromatin remodeling factor CHD8.The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.Somatic mutation as a mechanism of Wnt/β-catenin pathway activation in CLL.CHD7 functions in the nucleolus as a positive regulator of ribosomal RNA biogenesisRegulation of serum response factor activity and smooth muscle cell apoptosis by chromodomain helicase DNA-binding protein 8.Chromodomain helicase binding protein 8 (Chd8) is a novel A-kinase anchoring protein expressed during rat cardiac development.The autism-associated chromatin modifier CHD8 regulates other autism risk genes during human neurodevelopmentArchitects of the genome: CHD dysfunction in cancer, developmental disorders and neurological syndromesIdentification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex.A novel non-SET domain multi-subunit methyltransferase required for sequential nucleosomal histone H3 methylation by the mixed lineage leukemia protein-1 (MLL1) core complexPan-cancer network analysis identifies combinations of rare somatic mutations across pathways and protein complexesThe chromatin Remodeler CHD8 is required for activation of progesterone receptor-dependent enhancers.The autism-associated gene chromodomain helicase DNA-binding protein 8 (CHD8) regulates noncoding RNAs and autism-related genesSequencing chromosomal abnormalities reveals neurodevelopmental loci that confer risk across diagnostic boundaries.CRISPR/Cas9-mediated heterozygous knockout of the autism gene CHD8 and characterization of its transcriptional networks in neurodevelopment.
P2860
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P2860
CHD8 is an ATP-dependent chromatin remodeling factor that regulates beta-catenin target genes
description
2008 nî lūn-bûn
@nan
2008 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@ast
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@en
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@en-gb
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@nl
type
label
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@ast
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@en
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@en-gb
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@nl
prefLabel
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@ast
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@en
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@en-gb
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@nl
P2093
P2860
P921
P356
P1476
CHD8 is an ATP-dependent chrom ...... ates beta-catenin target genes
@en
P2093
Brandi A Thompson
Daniel A Bochar
Véronique Tremblay
P2860
P304
P356
10.1128/MCB.00322-08
P407
P577
2008-06-01T00:00:00Z