Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1 - Test2 - elhamkhani - TriplyDB

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

http://www.wikidata.org/entity/Q29614651

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The spectrum of SWI/SNF mutations, ubiquitous in human cancers Targeted next-generation sequencing of head and neck squamous cell carcinoma identifies novel genetic alterations in HPV+ and HPV- tumors Cancer genome landscapes A form of the metabolic syndrome associated with mutations in DYRK1B AXL mediates resistance to PI3Kα inhibition by activating the EGFR/PKC/mTOR axis in head and neck and esophageal squamous cell carcinomas NCG 4.0: the network of cancer genes in the era of massive mutational screenings of cancer genomes Patient-derived tumour xenografts as models for oncology drug development Network of Cancer Genes (NCG 3.0): integration and analysis of genetic and network properties of cancer genes Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma Stress-triggered atavistic reprogramming (STAR) addiction: driving force behind head and neck cancer?Immunotherapy for head and neck squamous cell carcinoma The etiologic spectrum of head and neck squamous cell carcinoma in young patients Does Notch play a tumor suppressor role across diverse squamous cell carcinomas?Chromodomain-helicase-DNA binding protein 5, 7 and pronecrotic mixed lineage kinase domain-like protein serve as potential prognostic biomarkers in patients with resected pancreatic adenocarcinomas Notch Signaling in Neuroendocrine Tumors HPV Positive Head and Neck Cancers: Molecular Pathogenesis and Evolving Treatment Strategies Squamous cell carcinomas of the lung and of the head and neck: new insights on molecular characterization Keeping a lid on nodal: transcriptional and translational repression of nodal signalling The Tip of the Iceberg: Clinical Implications of Genomic Sequencing Projects in Head and Neck Cancer Vav1: A Dr. Jekyll and Mr. Hyde protein--good for the hematopoietic system, bad for cancer Skin Carcinogenesis Studies Using Mouse Models with Altered Polyamines.Biomarkers of head and neck cancer, tools or a gordian knot?The complexity of epigenetic diseases Next-generation sequencing: hype and hope for development of personalized radiation therapy?Molecular cancer prevention: Current status and future directions Targeted Therapy in Oropharyngeal Squamous Cell Carcinoma: The Implications of HPV for Therapy Mutational signatures: the patterns of somatic mutations hidden in cancer genomes Nucleic acid targeting: towards personalized therapy for head and neck cancer.Protein-intrinsic and signaling network-based sources of resistance to EGFR- and ErbB family-targeted therapies in head and neck cancer Protein N-glycosylation in oral cancer: dysregulated cellular networks among DPAGT1, E-cadherin adhesion and canonical Wnt signaling Early phase clinical trials to identify optimal dosing and safety Disease gene identification strategies for exome sequencing Profiling invasiveness in head and neck cancer: recent contributions of genomic and transcriptomic approaches Genomic landscape of human papillomavirus-associated cancers Clinical application of genetics to guide prevention and treatment of oral diseases Notch signaling in prostate cancer: a moving target Human papillomavirus induced transformation in cervical and head and neck cancers Therapeutic insights from genomic studies of head and neck squamous cell carcinomas Primary chemotherapy and radiation as a treatment strategy for HPV-positive oropharyngeal cancer Lessons learned from next-generation sequencing in head and neck cancer

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Exome sequencing of head and neck squamous cell carcinoma reveals inactivating mutations in NOTCH1

http://www.wikidata.org/entity/Q29614651

description

2011 nî lūn-bûn

@nan

2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

2011 թվականի օգոստոսին հրատարակված գիտական հոդված

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2011年の論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年論文

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2011年论文

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name

Exome sequencing of head and n ...... activating mutations in NOTCH1

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Exome sequencing of head and n ...... activating mutations in NOTCH1

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Exome sequencing of head and n ...... activating mutations in NOTCH1

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Exome sequencing of head and n ...... activating mutations in NOTCH1

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Exome sequencing of head and n ...... activating mutations in NOTCH1

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Exome sequencing of head and n ...... activating mutations in NOTCH1

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Exome sequencing of head and n ...... activating mutations in NOTCH1

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Adel K El-Naggar

http://www.w3.org/2001/XMLSchema#string

Bert Vogelstein

http://www.w3.org/2001/XMLSchema#string

Carole Fakhry

http://www.w3.org/2001/XMLSchema#string

Chetan Bettegowda

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David A Wheeler

http://www.w3.org/2001/XMLSchema#string

David Sidransky

http://www.w3.org/2001/XMLSchema#string

Donna M Muzny

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Jeffrey N Myers

http://www.w3.org/2001/XMLSchema#string

Jennifer A Drummond

http://www.w3.org/2001/XMLSchema#string

Jiexin Zhang

http://www.w3.org/2001/XMLSchema#string

P2860

TAN-1, the human homolog of the Drosophila notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

Exome sequencing identifies frequent mutation of the SWI/SNF complex gene PBRM1 in renal carcinoma

Alterations of the Notch pathway in lung cancer.

Human papillomavirus and survival of patients with oropharyngeal cancer.

Cancer statistics, 2010

Global cancer statistics, 2002

Oncogenic forms of NOTCH1 lacking either the primary binding site for RBP-Jkappa or nuclear localization sequences retain the ability to associate with RBP-Jkappa and activate transcription

Case-control study of human papillomavirus and oropharyngeal cancer

DAXX/ATRX, MEN1, and mTOR pathway genes are frequently altered in pancreatic neuroendocrine tumors

The canonical Notch signaling pathway: unfolding the activation mechanism.

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1154-1157

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170820

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10.1126/SCIENCE.1206923

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6046

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333

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Ralph H. Hruban

Curtis R Pickering

Victor Velculescu

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2011-07-28T00:00:00Z

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51530328

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21798897

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3162986

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