about
Replication slippage of the thermophilic DNA polymerases B and D from the Euryarchaeota Pyrococcus abyssiAntimutator alleles of yeast DNA polymerase gamma modulate the balance between DNA synthesis and excisionThe major roles of DNA polymerases epsilon and delta at the eukaryotic replication fork are evolutionarily conservedNatural selection fails to optimize mutation rates for long-term adaptation on rugged fitness landscapesGenetic progression and the waiting time to cancerDNA replication at the single-molecule levelA unique error signature for human DNA polymerase nuPhi29 DNA polymerase residues Tyr59, His61 and Phe69 of the highly conserved ExoII motif are essential for interaction with the terminal proteinAltered nucleotide misinsertion fidelity associated with poliota-dependent replication at the end of a DNA template.Unique misinsertion specificity of poliota may decrease the mutagenic potential of deaminated cytosinesTranslesion replication of benzo[a]pyrene and benzo[c]phenanthrene diol epoxide adducts of deoxyadenosine and deoxyguanosine by human DNA polymerase iotaInvolvement of phi29 DNA polymerase thumb subdomain in the proper coordination of synthesis and degradation during DNA replicationMutational analysis of the damage-recognition and catalytic mechanism of human SMUG1 DNA glycosylaseThe 3'-->5' exonuclease of DNA polymerase delta can substitute for the 5' flap endonuclease Rad27/Fen1 in processing Okazaki fragments and preventing genome instabilityThe fidelity of DNA synthesis by eukaryotic replicative and translesion synthesis polymerasesSlipping and sliding: frameshift mutations in herpes simplex virus thymidine kinase and drug-resistanceSelection of an improved RNA polymerase ribozyme with superior extension and fidelityHuman cancers express a mutator phenotypeMechanisms of accurate translesion synthesis by human DNA polymerase etaStable complexes formed by HIV-1 reverse transcriptase at distinct positions on the primer-template controlled by binding deoxynucleoside triphosphates or foscarnetSurface plasmon field-enhanced fluorescence spectroscopy studies of primer extension reactions.8-vinyl-deoxyadenosine, an alternative fluorescent nucleoside analog to 2'-deoxyribosyl-2-aminopurine with improved propertiesNucleotide modification at the gamma-phosphate leads to the improved fidelity of HIV-1 reverse transcriptase.Physiology of the read-write genomeMassively parallel sequencing: the new frontier of hematologic genomicsStructure-function studies of DNA polymerase λDNA polymerase delta in DNA replication and genome maintenanceCancer evolution: mathematical models and computational inferenceAre there errors in glycogen biosynthesis and is laforin a repair enzyme?Modeling evolutionary dynamics of epigenetic mutations in hierarchically organized tumorsProcessive DNA synthesis observed in a polymerase crystal suggests a mechanism for the prevention of frameshift mutations.The structural basis for the mutagenicity of O6-methyl-guanine lesionsStructures of DNA Polymerase β with Active-Site Mismatches Suggest a Transient Abasic Site Intermediate during MisincorporationVariation in Mutation Rates Caused by RB69pol Fidelity Mutants Can Be Rationalized on the Basis of Their Kinetic Behavior and Crystal StructuresReplication infidelity via a mismatch with Watson–Crick geometryStructural evidence for the rare tautomer hypothesis of spontaneous mutagenesisDNA Mismatch Synthesis Complexes Provide Insights into Base Selectivity of a B Family DNA PolymeraseBidentate and tridentate metal-ion coordination states within ternary complexes of RB69 DNA polymeraseStructural Basis for Differential Insertion Kinetics of dNMPs Opposite a Difluorotoluene Nucleotide ResidueCrystal Structure and Mode of Helicase Binding of the C-Terminal Domain of Primase from Helicobacter pylori
P2860
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P2860
description
2000 nî lūn-bûn
@nan
2000 թուականին հրատարակուած գիտական յօդուած
@hyw
2000 թվականին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
DNA replication fidelity
@ast
DNA replication fidelity
@en
type
label
DNA replication fidelity
@ast
DNA replication fidelity
@en
prefLabel
DNA replication fidelity
@ast
DNA replication fidelity
@en
P3181
P1476
DNA replication fidelity
@en
P2093
P304
P3181
P356
10.1146/ANNUREV.BIOCHEM.69.1.497
P407
P577
2000-01-01T00:00:00Z