Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum
about
What do human parasites do with a chloroplast anyway?Genome sequence and comparative analysis of the model rodent malaria parasite Plasmodium yoelii yoeliiGenome sequence of the human malaria parasite Plasmodium falciparum1,2-dithiole-3-ones as potent inhibitors of the bacterial 3-ketoacyl acyl carrier protein synthase III (FabH)The apicomplexan plastid and its evolutionBromopyrrole alkaloids as lead compounds against protozoan parasitesThe evolution, metabolism and functions of the apicoplastGlobal phenotypic screening for antimalarialsAn FtsH protease is recruited to the mitochondrion of Plasmodium falciparumChemical rescue of malaria parasites lacking an apicoplast defines organelle function in blood-stage Plasmodium falciparumStructural elucidation of the specificity of the antibacterial agent triclosan for malarial enoyl acyl carrier protein reductaseStudies ofToxoplasma gondiiandPlasmodium falciparumenoyl acyl carrier protein reductase and implications for the development of antiparasitic agentsX-ray structural analysis of Plasmodium falciparum enoyl acyl carrier protein reductase as a pathway toward the optimization of triclosan antimalarial efficacyType I and type II fatty acid biosynthesis in Eimeria tenella: enoyl reductase activity and structureThe Fatty Acid Biosynthesis Enzyme FabI Plays a Key Role in the Development of Liver-Stage Malarial ParasitesTriclosan Derivatives: Towards Potent Inhibitors of Drug-Sensitive and Drug-ResistantMycobacterium tuberculosisIdentification and Development of Novel Inhibitors of Toxoplasma gondii Enoyl ReductaseEffect of substrate binding loop mutations on the structure, kinetics, and inhibition of enoyl acyl carrier protein reductase from Plasmodium falciparumCrystallographic Study of Novel Transthyretin Ligands Exhibiting Negative-Cooperativity between Two Thyroxine Binding SitesThe benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme targetAnalogs of natural aminoacyl-tRNA synthetase inhibitors clear malaria in vivoApicoplast lipoic acid protein ligase B is not essential for Plasmodium falciparumDual-resolution molecular dynamics simulation of antimicrobials in biomembranesEvidence-based annotation of the malaria parasite's genome using comparative expression profilingOleic acid biosynthesis in Plasmodium falciparum: characterization of the stearoyl-CoA desaturase and investigation as a potential therapeutic targetMultivariate PLS Modeling of Apicomplexan FabD-Ligand Interaction Space for Mapping Target-Specific Chemical Space and Pharmacophore FingerprintsOpportunities and Challenges in Antiparasitic Drug DiscoveryMembrane transporters in the relict plastid of malaria parasitesA role for falcilysin in transit peptide degradation in the Plasmodium falciparum apicoplastProcessing of an apicoplast leader sequence in Plasmodium falciparum and the identification of a putative leader cleavage enzymePlasmodium falciparum phospholipase C hydrolyzing sphingomyelin and lysocholinephospholipids is a possible target for malaria chemotherapyA single, bi-functional aquaglyceroporin in blood-stage Plasmodium falciparum malaria parasitesTropical infectious diseases: metabolic maps and functions of the Plasmodium falciparum apicoplastDelivery of antimicrobials into parasitesMass spectrometry-based systems approach for identification of inhibitors of Plasmodium falciparum fatty acid synthaseAbsorption, pharmacokinetics, and safety of triclosan after dermal administration.Enzymes of type II fatty acid synthesis and apicoplast differentiation and division in Eimeria tenella.Antimalarial drug targets in Plasmodium falciparum predicted by stage-specific metabolic network analysisMalaria parasite development in the mosquito and infection of the mammalian host.An update on the rapid advances in malaria parasite cell biology.
P2860
Q21145764-181E39E9-FC07-4E70-94B2-3CCE230AB43FQ22122512-18ED2013-DDC4-45A5-BE89-163ED1C6A5CEQ22122524-14E1824F-7538-4D9F-B5B6-37EF81C89997Q24564306-5DFF3951-AF36-4710-8EF2-9E54959271D5Q24631531-B7A5CE3D-DCE0-4939-B2C5-BCBB6927CD52Q24632744-854113E7-0FED-4B22-A4B8-21006582F71DQ24652914-D9C04D31-C2FB-4A8D-AB44-018252764496Q26824875-D549B431-132D-4201-ABE0-815CB24E5EFAQ27306879-64BA6C23-24F9-4741-B6BD-04254F1AE070Q27321104-628166F9-492C-4BB9-83E6-826E56E961E7Q27637344-CD1832AE-3AA6-4876-AC94-48E5402A774AQ27643926-EE6B2E54-2720-45E5-9886-B1556357BED1Q27645777-9E0F2704-63C0-46F3-98FA-D884C1A4B696Q27647201-69DE59E4-9859-4006-914D-797F9CE4D343Q27653089-CAE262B0-CF90-4F61-838F-0216954BE3A5Q27653366-1E944BCC-B815-451E-9CE9-BF35D3ADE7BAQ27664019-A6C9370B-E88C-4A17-A9F4-D5D1EA807DCDQ27666619-C877F708-91D4-459B-A3D6-102AADCBACA4Q27673044-E163710D-75B6-4E64-A413-48A6EB0B20F6Q27681222-75A5B53F-3EE9-4480-94FB-2DA005325B8BQ27861933-4ED5A86D-8B4B-4D2D-8964-4D6EF5B55503Q27973716-02F2E848-63B7-4316-8967-C5D926BEB4DEQ28299896-5BAB3436-35FB-498E-81CC-7954D7DBFD43Q28472095-5800649D-C8FC-4523-9E1E-8217F3BFA49DQ28476054-520042ED-2355-4922-B03D-F5CDA2AC3ED1Q28550655-70CCE97C-9CAE-4CE0-A9B2-3E24BC61084FQ29999214-8E88E6AF-C44F-4922-898A-939AB86E06AAQ30039456-EED31643-009B-4665-84A1-181932470DCEQ30042129-C37625C5-F05F-4751-BAA4-A0E286E5687BQ30043573-9CE5CCCC-1586-4B2F-9C8F-587DC59E204EQ30044494-548F4FC7-343C-43E2-A9D1-34D6C35A4E64Q30045196-B7771CF6-F5BD-4F06-BB0C-451B44829DE2Q30080014-7C37716B-59DE-4877-B332-D78F5DF87759Q30493563-97B29CBF-CBE1-403B-AE66-006E43351DBCQ33283922-8FF203BA-82F1-44E1-98A9-C8E539284262Q33559133-D6693B48-C28C-4883-8021-CD2B7AE83BCDQ33579443-FCC773FD-8CB2-41FB-82ED-5432AA58AEE5Q33679330-7DEE0DF6-34EF-4C31-B148-216ACE54B205Q33738231-74E663BD-4B79-40E5-AC8F-66A720D4862BQ33905946-6770DDC0-F601-4633-A2AC-624265FC77D2
P2860
Triclosan offers protection against blood stages of malaria by inhibiting enoyl-ACP reductase of Plasmodium falciparum
description
2001 nî lūn-bûn
@nan
2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
Triclosan offers protection ag ...... ctase of Plasmodium falciparum
@ast
Triclosan offers protection ag ...... ctase of Plasmodium falciparum
@en
type
label
Triclosan offers protection ag ...... ctase of Plasmodium falciparum
@ast
Triclosan offers protection ag ...... ctase of Plasmodium falciparum
@en
prefLabel
Triclosan offers protection ag ...... ctase of Plasmodium falciparum
@ast
Triclosan offers protection ag ...... ctase of Plasmodium falciparum
@en
P921
P356
P1433
P1476
Triclosan offers protection ag ...... ctase of Plasmodium falciparum
@en
P2093
P2888
P304
P356
10.1038/84612
P407
P577
2001-02-01T00:00:00Z
P5875
P6179
1043078943