Recent advances in targeting viral proteases for the discovery of novel antivirals.
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The pharmacological landscape and therapeutic potential of serine hydrolases3C Protease of Enterovirus 68: Structure-Based Design of Michael Acceptor Inhibitors and Their Broad-Spectrum Antiviral Effects against PicornavirusesA highly scalable peptide-based assay system for proteomicsNew binding site conformations of the dengue virus NS3 protease accessed by molecular dynamics simulation.Design, synthesis, and in vitro evaluation of potential West Nile virus protease inhibitors based on the 1-oxo-1,2,3,4-tetrahydroisoquinoline and 1-oxo-1,2-dihydroisoquinoline scaffolds.A phenotypic assay to identify Chikungunya virus inhibitors targeting the nonstructural protein nsP2.CLCAs - a family of metalloproteases of intriguing phylogenetic distribution and with cases of substituted catalytic sites.Functional domains of the HK97 capsid maturation protease and the mechanisms of protein encapsidation.Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.Chemoproteomic profiling of host and pathogen enzymes active in choleraGardiquimod: a Toll-like receptor-7 agonist that inhibits HIV type 1 infection of human macrophages and activated T cells.Macrocyclic inhibitors of 3C and 3C-like proteases of picornavirus, norovirus, and coronavirus.West Nile virus drug discovery.Functional proteomics: application of mass spectrometry to the study of enzymology in complex mixtures.Activity based protein profiling to detect serine hydrolase alterations in virus infected cellsStructure-based antivirals for emerging and neglected RNA viruses: an emerging field for medicinal chemistry in academia.Macromolecular assembly-driven processing of the 2/3 cleavage site in the alphavirus replicase polyprotein.Expression and Cleavage of Middle East Respiratory Syndrome Coronavirus nsp3-4 Polyprotein Induce the Formation of Double-Membrane Vesicles That Mimic Those Associated with Coronaviral RNA Replication.
P2860
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P2860
Recent advances in targeting viral proteases for the discovery of novel antivirals.
description
2010 nî lūn-bûn
@nan
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Recent advances in targeting viral proteases for the discovery of novel antivirals.
@ast
Recent advances in targeting viral proteases for the discovery of novel antivirals.
@en
type
label
Recent advances in targeting viral proteases for the discovery of novel antivirals.
@ast
Recent advances in targeting viral proteases for the discovery of novel antivirals.
@en
prefLabel
Recent advances in targeting viral proteases for the discovery of novel antivirals.
@ast
Recent advances in targeting viral proteases for the discovery of novel antivirals.
@en
P1476
Recent advances in targeting viral proteases for the discovery of novel antivirals.
@en
P2093
Holger Steuber
P304
P356
10.2174/156802610790725470
P577
2010-01-01T00:00:00Z