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Anatomy of enzyme channelsCoupling between catalytic site and collective dynamics: a requirement for mechanochemical activity of enzymesStructural elements responsible for conversion of streptavidin to a pseudoenzymeActivation of nanoscale allosteric protein domain motion revealed by neutron spin echo spectroscopyA dynamic knockout reveals that conformational fluctuations influence the chemical step of enzyme catalysisDesign and engineering of an O(2) transport proteinThe "Transport Specificity Ratio": a structure-function tool to search the protein fold for loci that control transition state stability in membrane transport catalysisRotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxationEnzymes: An integrated view of structure, dynamics and functionFunctional Importance of Mobile Ribosomal ProteinsAllosteric activation transitions in enzymes and biomolecular motors: insights from atomistic and coarse-grained simulationsRole of substrate dynamics in protein prenylation reactionsEvolutionarily conserved linkage between enzyme fold, flexibility, and catalysisTrapping conformational states along ligand-binding dynamics of peptide deformylase: the impact of induced fit on enzyme catalysisCorresponding functional dynamics across the Hsp90 Chaperone family: insights from a multiscale analysis of MD simulationsCircadian KaiC phosphorylation: a multi-layer networkAn ordered water channel in Staphylococcus aureus FabI: unraveling the mechanism of substrate recognition and reduction.Discovering conformational sub-states relevant to protein functionStructures of the N-terminal modules imply large domain motions during catalysis by methionine synthaseThe molecular basis of glyphosate resistance by an optimized microbial acetyltransferaseExplaining an Unusually Fast Parasitic Enzyme: Folate Tail-Binding Residues Dictate Substrate Positioning and Catalysis in Cryptosporidium hominis Thymidylate Synthase † ‡Functional and Structural Roles of the Cys14–Cys38 Disulfide of Bovine Pancreatic Trypsin InhibitorAdaptive protein evolution grants organismal fitness by improving catalysis and flexibilityConformational sampling, catalysis, and evolution of the bacterial phosphotriesteraseRegulation of Response Regulator Autophosphorylation through Interdomain ContactsReactibodies generated by kinetic selection couple chemical reactivity with favorable protein dynamicsStructure of ALD1, a plant-specific homologue of the universal diaminopimelate aminotransferase enzyme of lysine biosynthesisStructural Basis for the Recognition of Mycolic Acid Precursors by KasA, a Condensing Enzyme and Drug Target from Mycobacterium TuberculosisStructural basis of thermal stability of the tungsten cofactor synthesis protein MoaB from Pyrococcus furiosusThe role of distant mutations and allosteric regulation on LovD active site dynamicsCapture of a third Mg²⁺ is essential for catalyzing DNA synthesisProtein sectors: evolutionary units of three-dimensional structureAt the dawn of the 21st century: Is dynamics the missing link for understanding enzyme catalysis?Evolutionary information for specifying a protein foldNanoscale protein dynamics: a new frontier for neutron spin echo spectroscopyHot spots for allosteric regulation on protein surfacesStructural position correlation analysis (SPCA) for protein familyIntrinsic dynamics of an enzyme underlies catalysisCharacterizing the role of ensemble modulation in mutation-induced changes in binding affinitySimultaneous determination of protein structure and dynamics.
P2860
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P2860
description
2003 nî lūn-bûn
@nan
2003 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
A perspective on enzyme catalysis.
@ast
A perspective on enzyme catalysis.
@en
type
label
A perspective on enzyme catalysis.
@ast
A perspective on enzyme catalysis.
@en
prefLabel
A perspective on enzyme catalysis.
@ast
A perspective on enzyme catalysis.
@en
P356
P1433
P1476
A perspective on enzyme catalysis.
@en
P2093
Stephen J Benkovic
P304
P356
10.1126/SCIENCE.1085515
P407
P577
2003-08-01T00:00:00Z