Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.
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Identification of a broad-spectrum antiviral small molecule against severe acute respiratory syndrome coronavirus and Ebola, Hendra, and Nipah viruses by using a novel high-throughput screening assayModeling Influenza Virus Infection: A Roadmap for Influenza ResearchDESC1 and MSPL activate influenza A viruses and emerging coronaviruses for host cell entry.Tetherin Sensitivity of Influenza A Viruses Is Strain Specific: Role of Hemagglutinin and Neuraminidase.TMPRSS2 Independency for Haemagglutinin Cleavage In Vivo Differentiates Influenza B Virus from Influenza A Virus.The host protease TMPRSS2 plays a major role in in vivo replication of emerging H7N9 and seasonal influenza viruses.Non-human primate orthologues of TMPRSS2 cleave and activate the influenza virus hemagglutinin.A Lipopolysaccharide from Pantoea Agglomerans Is a Promising Adjuvant for Sublingual Vaccines to Induce Systemic and Mucosal Immune Responses in Mice via TLR4 Pathway.A serpin shapes the extracellular environment to prevent influenza A virus maturationA mutant H3N2 influenza virus uses an alternative activation mechanism in TMPRSS2 knockout mice by loss of an oligosaccharide in the hemagglutinin stalk region.The Hemagglutinin of Bat-Associated Influenza Viruses Is Activated by TMPRSS2 for pH-Dependent Entry into Bat but Not Human Cells.Respiratory protease/antiprotease balance determines susceptibility to viral infection and can be modified by nutritional antioxidantsCathepsin L Helps to Defend Mice from Infection with Influenza A.Different residues in the SARS-CoV spike protein determine cleavage and activation by the host cell protease TMPRSS2.Host genetics of severe influenza: from mouse Mx1 to human IRF7The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases.Identification of Nafamostat as a Potent Inhibitor of Middle East Respiratory Syndrome Coronavirus S Protein-Mediated Membrane Fusion Using the Split-Protein-Based Cell-Cell Fusion Assay.TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 influenza A virus in mice.Antiviral strategies against influenza virus: towards new therapeutic approaches.The oncogene ERG: a key factor in prostate cancer.Kallikrein-Related Peptidase 5 Contributes to H3N2 Influenza Virus Infection in Human Lungs.TMPRSS2 Isoform 1 Activates Respiratory Viruses and Is Expressed in Viral Target Cells.Transmembrane serine protease TMPRSS2 activates hepatitis C virus infection.Type II transmembrane serine proteases as potential target for anti-influenza drug discovery.Coronavirus and influenza virus proteolytic priming takes place in tetraspanin-enriched membrane microdomainsModification of the hemagglutinin cleavage site allows indirect activation of avian influenza virus H9N2 by bacterial staphylokinaseZygote injection of CRISPR/Cas9 RNA successfully modifies the target gene without delaying blastocyst development or altering the sex ratio in pigs.Enterokinase Enhances Influenza A Virus Infection by Activating Trypsinogen in Human Cell Lines.TMPRSS11A activates the influenza A virus hemagglutinin and the MERS coronavirus spike protein and is insensitive against blockade by HAI-1Exchange of amino acids in the H1-haemagglutinin to H3 residues is required for efficient influenza A virus replication and pathology in Tmprss2 knock-out mice
P2860
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P2860
Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.
description
2013 nî lūn-bûn
@nan
2013 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
@wuu
name
Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.
@ast
Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.
@en
type
label
Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.
@ast
Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.
@en
prefLabel
Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.
@ast
Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.
@en
P2093
P2860
P50
P1433
P1476
Tmprss2 is essential for influenza H1N1 virus pathogenesis in mice.
@en
P2093
Bastian Hatesuer
Nora Mehnert
Peter S Nelson
Stephanie Bertram
P2860
P304
P356
10.1371/JOURNAL.PPAT.1003774
P577
2013-12-05T00:00:00Z