Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
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TM6SF2 is a regulator of liver fat metabolism influencing triglyceride secretion and hepatic lipid droplet contentNutrigenetics and Nutrimiromics of the Circadian System: The Time for Human HealthRecent advances in the molecular genetics of type 2 diabetes mellitusTrans-ethnic genome-wide association studies: advantages and challenges of mapping in diverse populations.Health disparities in endocrine disorders: biological, clinical, and nonclinical factors--an Endocrine Society scientific statementUncovering physiological mechanisms for health disparities in type 2 diabetesGenome-wide association study of bipolar disorder accounting for effect of body mass index identifies a new risk allele in TCF7L2Genome-wide trans-ancestry meta-analysis provides insight into the genetic architecture of type 2 diabetes susceptibility2017 update on the relationship between diabetes and colorectal cancer: epidemiology, potential molecular mechanisms and therapeutic implicationsA novel TCF7L2 type 2 diabetes SNP identified from fine mapping in African American women.Causal effects of body mass index on cardiometabolic traits and events: a Mendelian randomization analysis.Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.Gene-centric meta-analysis of lipid traits in African, East Asian and Hispanic populations.Finding type 2 diabetes causal single nucleotide polymorphism combinations and functional modules from genome-wide association data.metabolicMine: an integrated genomics, genetics and proteomics data warehouse for common metabolic disease research.Biomarkers for combat-related PTSD: focus on molecular networks from high-dimensional data.Efficacy and safety of liraglutide, a once-daily human glucagon-like peptide-1 receptor agonist, in African-American people with Type 2 diabetes: a meta-analysis of sub-population data from seven phase III trials.Evaluation of common type 2 diabetes risk variants in a South Asian population of Sri Lankan descentGenetics of type 2 diabetes in European populations.The contribution of biogeographical ancestry and socioeconomic status to racial/ethnic disparities in type 2 diabetes mellitus: results from the Boston Area Community Health SurveySREBF1 gene variations modulate insulin sensitivity in response to a fish oil supplementationIdentification of HKDC1 and BACE2 as genes influencing glycemic traits during pregnancy through genome-wide association studies.Maternal and offspring fasting glucose and type 2 diabetes-associated genetic variants and cognitive function at age 8: a Mendelian randomization study in the Avon Longitudinal Study of Parents and Children.Can genetic pleiotropy replicate common clinical constellations of cardiovascular disease and risk?A variant in the ABO gene explains the variation in soluble E-selectin levels-results from dense genotyping in two independent populations.TCF7L2 is a master regulator of insulin production and processing.Replication of type 2 diabetes candidate genes variations in three geographically unrelated Indian population groups.Intervention in the context of development: pathways toward new treatments.Antiretroviral therapy modifies the genetic effect of known type 2 diabetes-associated risk variants in HIV-infected women.High trans-ethnic replicability of GWAS results implies common causal variants.The TCF7L2 rs7903146 (T) allele is associated with type 2 diabetes in urban Ghana: a hospital-based case-control study.Atenolol induced HDL-C change in the pharmacogenomic evaluation of antihypertensive responses (PEAR) study.Contribution of SLC30A8 variants to the risk of type 2 diabetes in a multi-ethnic population: a case control study.Large-scale gene-centric analysis identifies polymorphisms for resistant hypertension.Novel genomic signals of recent selection in an Ethiopian population.16S gut community of the Cameron County Hispanic Cohort.Pathways targeted by antidiabetes drugs are enriched for multiple genes associated with type 2 diabetes riskGenetics of type 2 diabetes-pitfalls and possibilities.Evidence of non-pancreatic beta cell-dependent roles of Tcf7l2 in the regulation of glucose metabolism in miceGenome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat.
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P2860
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
description
2012 nî lūn-bûn
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2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
@ast
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
@en
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
@en-gb
type
label
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
@ast
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
@en
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
@en-gb
prefLabel
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
@ast
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
@en
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
@en-gb
P2093
P2860
P50
P1476
Large-scale gene-centric meta-analysis across 39 studies identifies type 2 diabetes loci
@en
P2093
Alex Reiner
Anke-Hilse Maitland-van der Zee
Annemieke W M Spijkerman
Anthonius de Boer
Archana Tare
Ashok Balasubramanyam
Asif Rasheed
Bernhard O Böhm
Berta Almoguera Castillo
P2860
P304
P356
10.1016/J.AJHG.2011.12.022
P407
P50
P577
2012-02-09T00:00:00Z