The c-Abl tyrosine kinase regulates actin remodeling at the immune synapse
about
Hematopoietic lineage cell-specific protein 1 functions in concert with the Wiskott-Aldrich syndrome protein to promote podosome array organization and chemotaxis in dendritic cellsInteractions among HCLS1, HAX1 and LEF-1 proteins are essential for G-CSF-triggered granulopoiesisABL tyrosine kinases: evolution of function, regulation, and specificityRegulation of cell migration and morphogenesis by Abl-family kinases: emerging mechanisms and physiological contextsCritical role of actin-associated proteins in smooth muscle contraction, cell proliferation, airway hyperresponsiveness and airway remodelingPhosphoregulation of the WAVE regulatory complex and signal integrationWASp family verprolin-homologous protein-2 (WAVE2) and Wiskott-Aldrich syndrome protein (WASp) engage in distinct downstream signaling interactions at the T cell antigen receptor siteTyrosine kinases EnAbling adaptor molecules for chemokine-induced Rap1 activation in T cellsRole played by paxillin and paxillin tyrosine phosphorylation in hepatocyte growth factor/sphingosine-1-phosphate-mediated reactive oxygen species generation, lamellipodia formation, and endothelial barrier functionc-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expressionc-Abl-deficient mice exhibit reduced numbers of peritoneal B-1 cells and defects in BCR-induced B cell activationArg interacts with cortactin to promote adhesion-dependent cell edge protrusionAbl family kinases regulate FcγR-mediated phagocytosis in murine macrophagesThe Abl and Arg kinases mediate distinct modes of phagocytosis and are required for maximal Leishmania infectionAbelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis.Avian influenza viruses inhibit the major cellular signalling integrator c-Abl.c-Abl tyrosine kinase plays a critical role in β2 integrin-dependent neutrophil migration by regulating Vav1 activity.Enhancement of ABL kinase catalytic efficiency by a direct binding regulator is independent of other regulatory mechanisms.Nonstructural protein 1 (NS1)-mediated inhibition of c-Abl results in acute lung injury and priming for bacterial co-infections: insights into 1918 H1N1 pandemic?Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1Hematopoietic lineage cell-specific protein 1 is recruited to the immunological synapse by IL-2-inducible T cell kinase and regulates phospholipase Cgamma1 Microcluster dynamics during T cell spreadingCRK proteins selectively regulate T cell migration into inflamed tissues.Kinase activity profiling of pneumococcal pneumoniaIL-2 induces a WAVE2-dependent pathway for actin reorganization that enables WASp-independent human NK cell function.T cell survival and function requires the c-Abl tyrosine kinaseActin engine in immunological synapseRole of c-Abl in L-selectin shedding from the neutrophil surfaceThe WAVE2 complex regulates T cell receptor signaling to integrins via Abl- and CrkL-C3G-mediated activation of Rap1.Tec kinases regulate T-lymphocyte development and function: new insights into the roles of Itk and Rlk/TxkAbl tyrosine kinases in T-cell signalingRole of Abl in airway hyperresponsiveness and airway remodeling.Tyrosine kinase c-Abl regulates the survival of plasma cellsSDF1 reduces interneuron leading process branching through dual regulation of actin and microtubulesThe capable ABL: what is its biological function?Hax-1: a regulator of calcium signaling and apoptosis progression with multiple roles in human disease.Lymphocytes from chronic lymphocytic leukaemia undergo ABL1-linked amoeboid motility and homotypic interaction as an early adaptive change to ex vivo culture.Aberrant Th2 inflammation drives dysfunction of alveolar macrophages and susceptibility to bacterial pneumonia.The Abl-1 Kinase is Dispensable for NK Cell Inhibitory Signalling and is not Involved in Murine NK Cell Education.The Src kinases Hck, Fgr and Lyn activate Arg to facilitate IgG-mediated phagocytosis and Leishmania infection.c-Abl and Src-family kinases cross-talk in regulation of myeloid cell migration
P2860
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P2860
The c-Abl tyrosine kinase regulates actin remodeling at the immune synapse
description
2008 nî lūn-bûn
@nan
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
The c-Abl tyrosine kinase regulates actin remodeling at the immune synapse
@ast
The c-Abl tyrosine kinase regulates actin remodeling at the immune synapse
@en
type
label
The c-Abl tyrosine kinase regulates actin remodeling at the immune synapse
@ast
The c-Abl tyrosine kinase regulates actin remodeling at the immune synapse
@en
prefLabel
The c-Abl tyrosine kinase regulates actin remodeling at the immune synapse
@ast
The c-Abl tyrosine kinase regulates actin remodeling at the immune synapse
@en
P2093
P2860
P1433
P1476
The c-Abl tyrosine kinase regulates actin remodeling at the immune synapse
@en
P2093
Anthony J Koleske
Erin O Comiskey
Renell S Dupree
Shuixing Li
Yanping Huang
P2860
P304
P356
10.1182/BLOOD-2007-10-118232
P407
P577
2008-02-27T00:00:00Z