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Rap2A links intestinal cell polarity to brush border formationRadixin assembles cAMP effectors Epac and PKA into a functional cAMP compartment: role in cAMP-dependent cell proliferationRole of guanine-nucleotide exchange factor Epac in renal physiology and pathophysiologyExchange protein directly activated by cAMP encoded by the mammalian rapgef3 gene: Structure, function and therapeuticsThe interaction of Epac1 and Ran promotes Rap1 activation at the nuclear envelope.Rap1 Spatially Controls ArhGAP29 To Inhibit Rho Signaling during Endothelial Barrier Regulation.Divergent label-free cell phenotypic pharmacology of ligands at the overexpressed β₂-adrenergic receptors.Recent insights into cerebral cavernous malformations: a complex jigsaw puzzle under construction.Phosphodiesterase Inhibitors as a Therapeutic Approach to Neuroprotection and Repair.Control of cell adhesion dynamics by Rap1 signaling.beta-Arrestin-dependent activation of Ca(2+)/calmodulin kinase II after beta(1)-adrenergic receptor stimulation.[EXPRESS] Epac and Nociceptor Sensitization.Spatial regulation of cyclic AMP-Epac1 signaling in cell adhesion by ERM proteins.TLR signaling paralyzes monocyte chemotaxis through synergized effects of p38 MAPK and global Rap-1 activationMechanism of intracellular cAMP sensor Epac2 activation: cAMP-induced conformational changes identified by amide hydrogen/deuterium exchange mass spectrometry (DXMS).cAMP regulates DEP domain-mediated binding of the guanine nucleotide exchange factor Epac1 to phosphatidic acid at the plasma membraneCell signalling in insulin secretion: the molecular targets of ATP, cAMP and sulfonylurea.DNA methylation of alternative promoters directs tissue specific expression of Epac2 isoformsThe nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.Novel Epac fluorescent ligand reveals distinct Epac1 vs. Epac2 distribution and function in cardiomyocytes.Heat-labile enterotoxin-induced activation of NF-κB and MAPK pathways in intestinal epithelial cells impacts enterotoxigenic Escherichia coli (ETEC) adherence.Reevaluating αE-catenin monomer and homodimer functions by characterizing E-cadherin/αE-catenin chimeras.Critical role for Epac1 in inflammatory pain controlled by GRK2-mediated phosphorylation of Epac1.Epac1 interacts with importin β1 and controls neurite outgrowth independently of cAMP and Rap1.The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function.Roles of Rap1 signaling in tumor cell migration and invasionEzrin, Radixin and Moesin: key regulators of membrane-cortex interactions and signalingBiological roles of cAMP: variations on a theme in the different kingdoms of life.Caged nucleotides/nucleosides and their photochemical biology.cAMP signalling in the vasculature: the role of Epac (exchange protein directly activated by cAMP).Epac proteins: specific ligands and role in cardiac remodelling.Purinergic A2b Receptor Activation by Extracellular Cues Affects Positioning of the Centrosome and Nucleus and Causes Reduced Cell Migration.The role of Epac in the heart.Beta-Adrenoceptor Activation Reduces Both Dermal Microvascular Endothelial Cell Migration via a cAMP-Dependent Mechanism and Wound Angiogenesis.Inhibition of ATP release from erythrocytes: a role for EPACs and PKC.Cyclic nucleotide signaling is required during synaptic refinement at the Drosophila neuromuscular junction.Spatial control of Epac2 activity by cAMP and Ca2+-mediated activation of Ras in pancreatic β cells.Systems analysis of GLP-1 receptor signaling in pancreatic β-cells.Intracellular cAMP Sensor EPAC: Physiology, Pathophysiology, and Therapeutics Development.Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac.
P2860
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P2860
description
2009 nî lūn-bûn
@nan
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Direct spatial control of Epac1 by cyclic AMP.
@ast
Direct spatial control of Epac1 by cyclic AMP.
@en
type
label
Direct spatial control of Epac1 by cyclic AMP.
@ast
Direct spatial control of Epac1 by cyclic AMP.
@en
prefLabel
Direct spatial control of Epac1 by cyclic AMP.
@ast
Direct spatial control of Epac1 by cyclic AMP.
@en
P2093
P2860
P356
P1476
Direct spatial control of Epac1 by cyclic AMP.
@en
P2093
Bas Ponsioen
Holger Rehmann
Johannes L Bos
Martijn Gloerich
P2860
P304
P356
10.1128/MCB.01630-08
P407
P577
2009-03-09T00:00:00Z