Mechanisms of acute axonal degeneration in the optic nerve in vivo.
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Autophagy and heterophagy dysregulation leads to retinal pigment epithelium dysfunction and development of age-related macular degenerationOxidative stress induces autophagy in response to multiple noxious stimuli in retinal ganglion cellsThe role of soluble adenylyl cyclase in neurite outgrowthMicrofluidic chips for in vivo imaging of cellular responses to neural injury in Drosophila larvaeThe Evolving Functions of Autophagy in Ocular Health: A Double-edged SwordRole of the inositol 1,4,5-trisphosphate receptor/Ca2+-release channel in autophagyQuantitative and semi-quantitative measurements of axonal degeneration in tissue and primary neuron culturesA novel closed-body model of spinal cord injury caused by high-pressure air blasts produces extensive axonal injury and motor impairmentsCalpain-mediated cleavage of Beclin-1 and autophagy deregulation following retinal ischemic injury in vivoEarly and sustained activation of autophagy in degenerating axons after spinal cord injuryProcessing of optineurin in neuronal cellsMislocalization of neuronal mitochondria reveals regulation of Wallerian degeneration and NMNAT/WLD(S)-mediated axon protection independent of axonal mitochondria.Axon degeneration: Molecular mechanisms of a self-destruction pathwayLacritin and other autophagy associated proteins in ocular surface health.The lateral thoracic nerve and the cutaneous maximus muscle--a novel in vivo model system for nerve degeneration and regeneration studies.Autophagy induction stabilizes microtubules and promotes axon regeneration after spinal cord injury.Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degenerationViscoelasticity of tau proteins leads to strain rate-dependent breaking of microtubules during axonal stretch injury: predictions from a mathematical model.Ca2+ involvement in activation of extracellular-signal-regulated-kinase 1/2 and m-calpain after axotomy of the sciatic nerve.ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS.Rapamycin is neuroprotective in a rat chronic hypertensive glaucoma model.Imaging of rat optic nerve axons in vivo.Retrograde and Wallerian axonal degeneration occur synchronously after retinal ganglion cell axotomy.mTOR-Controlled Autophagy Requires Intracellular Ca(2+) SignalingDiffuse axonal injury in brain trauma: insights from alterations in neurofilaments.A splice variant of the human ion channel TRPM2 modulates neuroblastoma tumor growth through hypoxia-inducible factor (HIF)-1/2α.Changes to mitochondrial ultrastructure in optic nerve vulnerable to secondary degeneration in vivo are limited by irradiation at 670 nmAutophagy induction halts axonal degeneration in a mouse model of X-adrenoleukodystrophy.Diffusion tensor imaging detects retinal ganglion cell axon damage in the mouse model of optic nerve crush.In vivo evaluation of demyelination and remyelination in a nerve crush injury modelInfluence of viral vector-mediated delivery of superoxide dismutase and catalase to the hippocampus on spatial learning and memory during aging.Sensory neurons derived from diabetic rats have diminished internal Ca2+ stores linked to impaired re-uptake by the endoplasmic reticulum.Live Imaging of Calcium Dynamics during Axon Degeneration Reveals Two Functionally Distinct Phases of Calcium Influx.Activation of autophagy induces retinal ganglion cell death in a chronic hypertensive glaucoma model.Mitochondrial Ca(2+) signals in autophagy.Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons.Axonal Degeneration in Retinal Ganglion Cells Is Associated with a Membrane Polarity-Sensitive Redox Process.Novel roles for α-crystallins in retinal function and disease.A mouse ocular explant model that enables the study of living optic nerve head events after acute and chronic intraocular pressure elevation: Focusing on retinal ganglion cell axons and mitochondria.Molecular and Cellular Mechanisms of Axonal Regeneration After Spinal Cord Injury.
P2860
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P2860
Mechanisms of acute axonal degeneration in the optic nerve in vivo.
description
2010 nî lūn-bûn
@nan
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Mechanisms of acute axonal degeneration in the optic nerve in vivo.
@ast
Mechanisms of acute axonal degeneration in the optic nerve in vivo.
@en
type
label
Mechanisms of acute axonal degeneration in the optic nerve in vivo.
@ast
Mechanisms of acute axonal degeneration in the optic nerve in vivo.
@en
prefLabel
Mechanisms of acute axonal degeneration in the optic nerve in vivo.
@ast
Mechanisms of acute axonal degeneration in the optic nerve in vivo.
@en
P2093
P2860
P50
P356
P1476
Mechanisms of acute axonal degeneration in the optic nerve in vivo.
@en
P2093
Johanna Knöferle
Mathias Bähr
Polya Vutova
Thomas Ostendorf
Uwe Michel
Véronique Planchamp
Wolfgang Brück
P2860
P304
P356
10.1073/PNAS.0909794107
P407
P577
2010-03-15T00:00:00Z