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Guidelines for the use and interpretation of assays for monitoring autophagyGuidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's diseaseElevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cellsEarly and sustained activation of autophagy in degenerating axons after spinal cord injuryMechanisms of acute axonal degeneration in the optic nerve in vivo.Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degenerationROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS.Imaging of rat optic nerve axons in vivo.Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells.Alpha-synuclein mutations impair axonal regeneration in models of Parkinson's disease.The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice.JNK isoforms differentially regulate neurite growth and regeneration in dopaminergic neurons in vitro.Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons.Fasudil attenuates aggregation of α-synuclein in models of Parkinson's diseaseRho Kinase Inhibition with Fasudil in the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis-Symptomatic Treatment Potential after Disease Onset.ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.Axonal degeneration as a therapeutic target in the CNS.The role of autophagy in axonal degeneration of the optic nerve.Alpha-synuclein and iron: two keys unlocking Parkinson's disease.Collapsin response mediator protein-2 plays a major protective role in acute axonal degeneration.Clinical testing and spinal cord removal in a mouse model for amyotrophic lateral sclerosis (ALS)Acute axonal degeneration in vivo is attenuated by inhibition of autophagy in a calcium-dependent manner.Attenuation of Axonal Degeneration by Calcium Channel Inhibitors Improves Retinal Ganglion Cell Survival and Regeneration After Optic Nerve Crush.AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury.AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo.TGF-beta 1 enhances neurite outgrowth via regulation of proteasome function and EFABP.Hepatocyte growth factor protects retinal ganglion cells by increasing neuronal survival and axonal regeneration in vitro and in vivo.Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis.Elemental fingerprint as a cerebrospinal fluid biomarker for the diagnosis of Parkinson's disease.July 2017 ENCALS statement on edaravone.Plasmids containing NRSE/RE1 sites enhance neurite outgrowth of retinal ganglion cells via sequestration of REST independent of NRSE dsRNA expression.Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease.MDS1 and EVI1 complex locus (MECOM): a novel candidate gene for hereditary hematological malignancies.ROCK inhibition in models of neurodegeneration and its potential for clinical translation.Upregulation of reggie-1/flotillin-2 promotes axon regeneration in the rat optic nerve in vivo and neurite growth in vitro.Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)
P50
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P50
description
researcher
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ricercatore
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հետազոտող
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name
Jan C Koch
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Jan C Koch
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Jan C Koch
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Jan C Koch
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Jan C Koch
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label
Jan C Koch
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Jan C Koch
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Jan C Koch
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Jan C Koch
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Jan C Koch
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Jan Christoph Koch
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Jan-Christoph Koch
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Jan C Koch
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Jan C Koch
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Jan C Koch
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Jan C Koch
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Jan C Koch
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P214
P106
P21
P214
P31
P4012
P496
0000-0002-3778-0683
P734
P7859
viaf-89877176